Enzymatic Bioremediation of Organophosphate Compounds—Progress and Remaining Challenges DOI Creative Commons
Meghna Thakur, Igor L. Medintz, Scott A. Walper

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2019, Volume and Issue: 7

Published: Nov. 8, 2019

Organophosphate compounds are ubiquitously employed as agricultural pesticides and maintained chemical warfare agents by several nations. These highly toxic, show environmental persistence accumulation, contribute to numerous cases of poisoning death each year. While their use weapons mass destruction is rare, these never fully disappear into obscurity they continue be tools fear control governments terrorist organizations. Beyond weaponization, wide-scale dissemination products has led accumulation intoxication soil water across the globe. Therefore, there a dire need for rapid safe bioremediation, personal decontamination, therapeutic detoxicants. hydrolyzing enzymes emerging appealing targets satisfy decontamination needs owing ability hydrolyze both nerve using biologically-derived materials environment individual. As release genetically modified organisms not widely accepted practice, researchers exploring alternative strategies organophosphate bioremediation that focus on cell-free enzyme systems. In this review, we first discuss more prevalent organophosphorus along with research engineering efforts have an enhancement in activity, substrate tolerance, stability. later half advances achieved through focusing enhancing catalytic activity stability phosphotriesterase, model hydrolase, various approaches such nanoparticle display, DNA scaffolding, outer membrane vesicle encapsulation.

Language: Английский

Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications DOI Creative Commons
Ahmed Alengebawy, Sara Taha Abdelkhalek,

Sundas Rana Qureshi

et al.

Toxics, Journal Year: 2021, Volume and Issue: 9(3), P. 42 - 42

Published: Feb. 25, 2021

Environmental problems have always received immense attention from scientists. Toxicants pollution is a critical environmental concern that has posed serious threats to human health and agricultural production. Heavy metals pesticides are top of the list toxicants endangering nature. This review focuses on toxic effect heavy (cadmium (Cd), lead (Pb), copper (Cu), zinc (Zn)) (insecticides, herbicides, fungicides) adversely influencing ecosystem (plant soil) health. Furthermore, accumulation pesticide residues in soils plants been discussed detail. In addition, characteristics contaminated soil plant physiological parameters reviewed. Moreover, diseases caused by exposure were also reported. The bioaccumulation, mechanism action, transmission pathways both emphasized. bioavailability uptake these contaminants considered. Meanwhile, synergistic antagonistic interactions between their combined effects discussed. Previous relevant studies included cover all aspects this review. information provides deep insights into understanding hazardous effects.

Language: Английский

Citations

1495

An extensive review on the consequences of chemical pesticides on human health and environment DOI
Lata Rani,

Komal Thapa,

Neha Kanojia

et al.

Journal of Cleaner Production, Journal Year: 2020, Volume and Issue: 283, P. 124657 - 124657

Published: Oct. 14, 2020

Language: Английский

Citations

1038

Pesticides in Drinking Water—A Review DOI Open Access
Muhammad Syafrudin, Risky Ayu Kristanti, Adhi Yuniarto

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(2), P. 468 - 468

Published: Jan. 8, 2021

The ubiquitous problem of pesticide in aquatic environment are receiving worldwide concern as tends to accumulate the body organism and sediment soil, posing health risks human. Many formulations had introduced due rapid growth global market result from wide use pesticides agricultural non-agricultural sectors. occurrence water is derived by runoff field industrial wastewater. Soluble were carried away molecules especially during precipitation event percolating downward into soil layers eventually reach surface waters groundwater. Consequently, it degrades quality reduces supply clean for potable water. Long-time exposure low concentration resulted non-carcinogenic risks. conventional method treatment processes encompasses coagulation-flocculation, adsorption, filtration sedimentation, which rely on phase transfer pollutants. Those methods often incurred with a relatively high operational cost may cause secondary pollution such sludge formation. Advanced oxidation (AOPs) recognized technologies containing recalcitrant bio-refractory pollutants pesticides. It has been adopted recent purification technology because thermodynamic viability broad spectrum applicability. This work provides comprehensive review drinking its possible treatment.

Language: Английский

Citations

508

Global trends in pesticides: A looming threat and viable alternatives DOI
Akanksha Sharma, Ananya Shukla,

Kriti Attri

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2020, Volume and Issue: 201, P. 110812 - 110812

Published: June 5, 2020

Language: Английский

Citations

438

Pesticides: formulants, distribution pathways and effects on human health – a review DOI Creative Commons
Valeriya P. Kalyabina, Elena N. Esimbekova,

K. V. Kopylova

et al.

Toxicology Reports, Journal Year: 2021, Volume and Issue: 8, P. 1179 - 1192

Published: Jan. 1, 2021

Pesticides are commonly used in agriculture to enhance crop production and control pests. Therefore, pesticide residues can persist the environment agricultural crops. Although modern formulations relatively safe non-target species, numerous theoretical experimental data demonstrate that produce long-term negative effects on health of humans animals stability ecosystems. Of particular interest molecular mechanisms mediate start a cascade adverse effects. This is review latest literature consequences contamination crops by residues. In addition, we address issue implicit risks associated with formulations. The pesticides considered context Adverse Outcome Pathway concept.

Language: Английский

Citations

345

Factors Associated with Honey Bee Colony Losses: A Mini-Review DOI Creative Commons
Peter Hristov, Rositsa Shumkova,

Nadezhda Palova

et al.

Veterinary Sciences, Journal Year: 2020, Volume and Issue: 7(4), P. 166 - 166

Published: Oct. 30, 2020

The Western honey bee (Apis mellifera L., Hymenoptera: Apidae) is a species of crucial economic, agricultural and environmental importance. In the last ten years, some regions world have suffered from significant reduction colonies. fact, losses are not an unusual phenomenon, but in many countries worldwide there has been notable decrease cases USA, European countries, Middle East received considerable attention, mostly due to absence easily identifiable cause. It difficult determine main factors leading colony because bees’ diverse social behavior. Moreover, their daily routine, they make contact with agents environment exposed plethora human activities consequences. Nevertheless, various considered be contributing losses, recent investigations established most important ones, particular, pests diseases, management, including keeping practices breeding, change climatic conditions, practices, use pesticides. global picture highlights ectoparasitic mite Varroa destructor as major factor loss. Last least, microsporidian parasites, mainly Nosema ceranae, also contribute problem. Thus, it obvious that affecting globally. Increased monitoring scientific research should throw new light on involved losses. present review focuses which found impact increase

Language: Английский

Citations

247

Use of Botanical Pesticides in Agriculture as an Alternative to Synthetic Pesticides DOI Creative Commons
Patrick Maada Ngegba, Gaofeng Cui, Muhammad Zaryab Khalid

et al.

Agriculture, Journal Year: 2022, Volume and Issue: 12(5), P. 600 - 600

Published: April 24, 2022

Pest management is being confronted with immense economic and environmental issues worldwide because of massive utilization over-reliance on pesticides. The non-target toxicity, residual consequence, challenging biodegradability these synthetic pesticides have become a serious concern, which urgently requires the alternative prompt adoption sustainable cost-effective pest control measures. Increasing attention in safety has triggered interest approaches through eco-friendly plant-based Botanical pesticidal constituents are effective against myriads destructive pests diseases. More importantly, they widely available, inexpensive, accessible, rapidly biodegradable, little toxicity to beneficiary agents. phytochemical compositions diverse plant species responsible for their varying mechanisms action However, difficulties formulation insufficient appropriate chemical data led low level acceptance globally. Therefore, review seeks highlight status, compositions, insecticidal mechanisms, challenges pesticide usage agricultural production.

Language: Английский

Citations

219

An overview of the potential impacts of atrazine in aquatic environments: Perspectives for tailored solutions based on nanotechnology DOI
Felícia Pereira de Albuquerque, Jhones Luiz de Oliveira, Viviane Moschini‐Carlos

et al.

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 700, P. 134868 - 134868

Published: Nov. 1, 2019

Language: Английский

Citations

180

Metabolism and detoxification of pesticides in plants DOI
Jing Jing Zhang, Hong Yang

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 790, P. 148034 - 148034

Published: June 1, 2021

Language: Английский

Citations

170

Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data DOI Creative Commons
Michelle Leemans, Stephan Couderq, Barbara Demeneix

et al.

Frontiers in Endocrinology, Journal Year: 2019, Volume and Issue: 10

Published: Dec. 9, 2019

Plant Protection Products, more commonly referred to as pesticides and biocides, are used control a wide range of yield-reducing pests including insects, fungi, nematodes, weeds. Concern has been raised that some may act endocrine disrupting chemicals (EDCs) with the potential interfere hormone systems non-target invertebrates vertebrates, humans. EDCs at low doses particularly vulnerable periods exposure include pre- perinatal development. Of critical concern is number developing nervous system brain, notably thyroid signaling. Across orchestrates metamorphosis, brain development, metabolism. Pesticide action on homeostasis can involve interference TH production its control, displacement from distributor proteins liver Here we focused endpoints for each different classes reviewing epidemiological experimental studies carried out both in vivo vitro. We conclude first, many were placed market insufficient testing, other than acute or chronic toxicity, second, thyroid-specific neurodevelopmental effects mixture assessment largely absent regulatory directives.

Language: Английский

Citations

165