Exploring the antimicrobial activity of rare ginsenosides and the progress of their related pharmacological effects DOI
Wenting Wang,

Ya-jie Xue,

Jiankang Zhou

и другие.

Phytomedicine, Год журнала: 2024, Номер 133, С. 155904 - 155904

Опубликована: Авг. 4, 2024

Язык: Английский

Effects of Saponins on Lipid Metabolism: The Gut–Liver Axis Plays a Key Role DOI Open Access

Shixi Cao,

Mengqi Liu, Han Yao

и другие.

Nutrients, Год журнала: 2024, Номер 16(10), С. 1514 - 1514

Опубликована: Май 17, 2024

Unhealthy lifestyles (high-fat diet, smoking, alcohol consumption, too little exercise, etc.) in the current society are prone to cause lipid metabolism disorders affecting health of organism and inducing occurrence diseases. Saponins, as biologically active substances present plants, have lipid-lowering, inflammation-reducing, anti-atherosclerotic effects. Saponins thought be involved regulation body; it suppresses appetite and, thus, reduces energy intake by modulating pro-opiomelanocortin/Cocaine amphetamine regulated transcript (POMC/CART) neurons neuropeptide Y/agouti-related peptide (NPY/AGRP) hypothalamus, control center. directly activate AMP-activated protein kinase (AMPK) signaling pathway related transcriptional regulators such peroxisome-proliferator-activated-receptors (PPAR), CCAAT/enhancer-binding proteins (C/EBP), sterol-regulatory element binding (SREBP) increase fatty acid oxidation inhibit synthesis. It also modulates gut–liver interactions improve regulating gut microbes their metabolites derivatives—short-chain acids (SCFAs), bile (BAs), trimethylamine (TMA), lipopolysaccharide (LPS), et al. This paper reviews positive effects different saponins on disorders, suggesting that axis plays a crucial role improving processes may used therapeutic target provide new strategies for treating disorders.

Язык: Английский

Процитировано

7
Red Ginseng Attenuates the Hepatic Cellular Senescence in Aged Mice DOI Creative Commons
Da‐Yeon Lee,

Juliana Arndt,

Jennifer O’Connell

и другие.

Biology, Год журнала: 2024, Номер 13(1), С. 36 - 36

Опубликована: Янв. 8, 2024

Cellular senescence is defined as an irreversible cell cycle arrest accompanied by morphological and physiological alterations during aging. Red ginseng (RG), processed from fresh (

Язык: Английский

Процитировано

3
Chitosan-modified dihydromyricetin liposomes promote the repair of liver injury in mice suffering from diabetes mellitus DOI

Qiteng Ding,

Xinglong Liu, Shuai Zhang

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 273, С. 133040 - 133040

Опубликована: Июнь 10, 2024

Язык: Английский

Процитировано

2
Exploring the antimicrobial activity of rare ginsenosides and the progress of their related pharmacological effects DOI
Wenting Wang,

Ya-jie Xue,

Jiankang Zhou

и другие.

Phytomedicine, Год журнала: 2024, Номер 133, С. 155904 - 155904

Опубликована: Авг. 4, 2024

Язык: Английский

Процитировано

0