A novel antioxidant and anti-inflammatory carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol promotes the healing of radiation-combined wound skin injury in the 60Co γ-irradiated mice
Phytomedicine,
Год журнала:
2025,
Номер
unknown, С. 156790 - 156790
Опубликована: Апрель 1, 2025
Язык: Английский
Multifunctional carbomer based ferulic acid hydrogel promotes wound healing in radiation-induced skin injury by inactivating NLRP3 inflammasome
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Сен. 19, 2024
Язык: Английский
Cultured Chinese Giant Salamander Skin and Skin Secretions as a Source of Bioactive Peptides for Food and Medicine
Food Science of Animal Resources,
Год журнала:
2024,
Номер
45(1), С. 109 - 125
Опубликована: Ноя. 28, 2024
Amphibians
are
enjoyable
globally
for
their
culinary
value
and
increasingly
considered
alternative
protein
sources.
However,
the
skin
of
edible
amphibians,
especially
giant
salamanders,
is
often
discarded
without
much
thought.
this
underutilized
resource
holds
significant
potential
yielding
valuable
proteins
bioactive
peptides
(BPs).
These
peptides,
such
as
brevinins,
bombesins,
dermaseptins,
esculentins,
magainins,
temporins,
tigerinins,
salamandrins,
possess
a
wide
range
biological
activities,
including
antioxidant,
antimicrobial,
anticancer,
antidiabetic
properties.
This
review
provides
comprehensive
analysis
various
BPs
derived
from
salamander
or
secretions
associated
functions.
Furthermore,
it
examines
nutritional
composition
production
status,
challenges
surrounding
use
secretions.
also
explores
applications
these
in
food
biomedical
industries,
particularly
multifunctional
additives,
dietary
supplements,
drug
delivery
agents.
Язык: Английский
Mesenchymal Stem Cell Extract Promotes Skin Wound Healing
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(24), С. 13745 - 13745
Опубликована: Дек. 23, 2024
Recently,
it
has
been
reported
that
mesenchymal
stem
cell
(MSC)-derived
humoral
factors
promote
skin
wound
healing.
As
these
are
transiently
stored
in
cytoplasm,
we
collected
them
as
part
of
the
extracts
from
MSCs
(MSC-ext).
This
study
aimed
to
investigate
effects
MSC-ext
on
We
examined
proliferation
and
migration.
Additionally,
effect
healing
was
evaluated
using
a
mouse
defect
model.
The
enhanced
dermal
fibroblasts,
epithelial
cells,
endothelial
cells.
It
also
increased
number
migrating
fibroblasts
defects
treated
with
demonstrated
rapid
closure
compared
those
phosphate-buffered
saline.
group
exhibited
thicker
dermis,
larger
Picrosirius
red-positive
areas,
higher
Ki67-positive
Our
results
indicate
promotes
and/or
migration
enhances
suggests
therapeutic
potential
treating
novel
cell-free
treatment
modality.
Язык: Английский