Опубликована: Апрель 25, 2023
Assessing corneal biomechanics in vivo has long been a challenge the field of ophthalmology. Although recent wave-based optical coherence elastography (OCE) methods have shown promise this area, effect intraocular pressure (IOP) on mechanical wave propagation cornea remains unclear. To address this, we constructed an artificial eye model and performed surface OCE measurements radial directions (54–324°) silicone at varying IOP levels (10–40 mmHg). The results demonstrated increases speeds (mean ± STD) from 6.55 0.09 m/s (10 mmHg) to 9.82 0.19 (40 mmHg), leading estimate Young’s modulus, which increased exponentially 145.23 4.43 kPa 326.44 13.30 kPa. Our implementation highlighted that impact modulus (ΔE = 165.59 kPa, IOP: 10–40 was more significant than stretching 15.79 relative elongation: 0.98%–6.49%). study sheds light potential using research for biomechanics. Furthermore, it is critical consider measurement when utilizing clinical settings enhanced assessment
Язык: Английский