Corneal Surface Wave Propagation Associated with Intraocular Pressures: OCT Elastography Assessment in a Model Eye DOI Open Access

Guoqin Ma,

Jing Cai,

Rijian Zhong

et al.

Published: April 25, 2023

Assessing corneal biomechanics in vivo has long been a challenge the field of ophthalmology. Although recent wave-based optical coherence elastography (OCE) methods have shown promise this area, effect intraocular pressure (IOP) on mechanical wave propagation cornea remains unclear. To address this, we constructed an artificial eye model and performed surface OCE measurements radial directions (54–324°) silicone at varying IOP levels (10–40 mmHg). The results demonstrated increases speeds (mean ± STD) from 6.55 0.09 m/s (10 mmHg) to 9.82 0.19 (40 mmHg), leading estimate Young’s modulus, which increased exponentially 145.23 4.43 kPa 326.44 13.30 kPa. Our implementation highlighted that impact modulus (ΔE = 165.59 kPa, IOP: 10–40 was more significant than stretching 15.79 relative elongation: 0.98%–6.49%). study sheds light potential using research for biomechanics. Furthermore, it is critical consider measurement when utilizing clinical settings enhanced assessment

Language: Английский

Advances in Ophthalmic Engineering—Integrating Biomechanics, Tissue Engineering, and Imaging for the Future of Vision Science DOI Creative Commons

S Xin,

Zhuxin Xiong, Xiaofei Wang

et al.

Bioengineering, Journal Year: 2025, Volume and Issue: 12(4), P. 374 - 374

Published: April 2, 2025

Vision is one of the most essential senses, enabling individuals to interpret world around them [...]

Language: Английский

Citations

0
Corneal Surface Wave Propagation Associated with Intraocular Pressures: OCT Elastography Assessment in a Model Eye DOI Open Access

Guoqin Ma,

Jing Cai,

Rijian Zhong

et al.

Published: April 25, 2023

Assessing corneal biomechanics in vivo has long been a challenge the field of ophthalmology. Although recent wave-based optical coherence elastography (OCE) methods have shown promise this area, effect intraocular pressure (IOP) on mechanical wave propagation cornea remains unclear. To address this, we constructed an artificial eye model and performed surface OCE measurements radial directions (54–324°) silicone at varying IOP levels (10–40 mmHg). The results demonstrated increases speeds (mean ± STD) from 6.55 0.09 m/s (10 mmHg) to 9.82 0.19 (40 mmHg), leading estimate Young’s modulus, which increased exponentially 145.23 4.43 kPa 326.44 13.30 kPa. Our implementation highlighted that impact modulus (ΔE = 165.59 kPa, IOP: 10–40 was more significant than stretching 15.79 relative elongation: 0.98%–6.49%). study sheds light potential using research for biomechanics. Furthermore, it is critical consider measurement when utilizing clinical settings enhanced assessment

Language: Английский

Citations

2