Plants,
Год журнала:
2024,
Номер
13(19), С. 2801 - 2801
Опубликована: Окт. 6, 2024
The
increase
in
the
frequency
and
magnitude
of
environmental
stresses
poses
a
significant
risk
to
stability
food
supplies.
In
coastal
areas
Mediterranean,
brackish
water
has
long
been
considered
limitation
on
horticultural
production.
this
scenario,
use
biochar
agriculture
could
be
valuable
tool
cope
with
deleterious
effects
salt
stress.
This
work
aimed
investigate,
protected
environment,
different
concentrations
(0,
1,
2%
Pharmaceutics,
Год журнала:
2024,
Номер
16(4), С. 524 - 524
Опубликована: Апрель 10, 2024
The
skin
is
the
largest
organ
of
body,
and
it
acts
as
a
protective
barrier
against
external
factors.
Chronic
wounds
affect
millions
people
worldwide
are
associated
with
significant
morbidity
reduced
quality
life.
One
main
factors
involved
in
delayed
wound
healing
oxidative
injury,
which
triggered
by
overproduction
reactive
oxygen
species.
Oxidative
stress
has
been
implicated
pathogenesis
chronic
wounds,
where
known
to
impair
causing
damage
cellular
components,
delaying
inflammatory
phase
healing,
inhibiting
formation
new
blood
vessels.
Thereby,
treatment
requires
multidisciplinary
approach
that
addresses
underlying
causes
wound,
provides
optimal
care,
promotes
healing.
Among
promising
approaches
taking
care
antioxidants
gaining
interest
since
they
offer
multiple
benefits
related
health.
Therefore,
this
review,
we
will
highlight
latest
advances
use
natural
polymers
generate
tissue
regeneration
microenvironments
for
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(14), С. 7603 - 7603
Опубликована: Июль 11, 2024
This
article
presents
a
groundbreaking
perspective
on
carotenoids,
focusing
their
innovative
applications
and
transformative
potential
in
human
health
medicine.
Research
jointly
delves
deeper
into
the
bioactivity
bioavailability
of
revealing
therapeutic
uses
technological
advances
that
have
to
revolutionize
medical
treatments.
We
explore
pioneering
which
carotenoids
are
used
treat
chronic
diseases
such
as
cancer,
cardiovascular
disease,
age-related
macular
degeneration,
offering
novel
protective
mechanisms
benefits.
Our
study
also
shows
cutting-edge
innovations
carotenoid
extraction
bioavailability,
including
development
supramolecular
carriers
advanced
nanotechnology,
dramatically
improve
absorption
efficacy
these
compounds.
These
not
only
ensure
consistent
quality
but
tailor
therapies
each
patient's
needs,
paving
way
for
personalized
By
integrating
latest
scientific
discoveries
techniques,
this
research
provides
prospective
clinical
establishing
new
benchmark
future
studies
field.
findings
underscore
importance
optimizing
extraction,
administration,
bioactivity,
methods
develop
more
effective,
targeted,
treatments,
thus
visionary
insight
modern
practices.
Medicina,
Год журнала:
2024,
Номер
60(4), С. 563 - 563
Опубликована: Март 29, 2024
The
gastrointestinal
tract
is
inhabited
by
the
gut
microbiota.
main
phyla
are
Firmicutes
and
Bacteroidetes.
In
non-alcoholic
fatty
liver
disease,
now
renamed
metabolic
dysfunction-associated
disease
(MAFLD),
an
alteration
in
Bacteroidetes
abundance
promotes
its
pathogenesis
evolution
into
steatohepatitis,
cirrhosis,
hepatocellular
carcinoma.
For
this
reason,
early
treatment
necessary
to
counteract
progression.
aim
of
present
narrative
review
evaluate
different
therapeutic
approaches
MAFLD.
most
important
for
MAFLD
lifestyle
changes.
regard,
Mediterranean
diet
could
be
considered
gold
standard
prevention
contrast,
a
Western
should
discouraged.
Probiotics
fecal
microbiota
transplantation
seem
valid,
safe,
effective
alternatives
treatment.
However,
more
studies
with
longer
follow-up
larger
cohort
patients
needed
underline
contrasting
Lycopene
is
a
compound
of
colored
origin
that
shows
strong
antioxidant
activity.
The
ability
to
neutralize
free
radicals
by
lycopene
the
basis
its
pro-health
effect,
including
inhibit
development
many
civilization
diseases.
Therefore,
this
study
focuses
on
importance
effect
in
inhibiting
such
diseases
as
cardiovascular
diseases,
etiology
etiology,
within
nervous
system.
Journal of Fungi,
Год журнала:
2024,
Номер
10(9), С. 616 - 616
Опубликована: Авг. 29, 2024
,
as
a
macrofungus
with
both
medicinal
and
dietary
applications,
is
renowned
for
its
rich
content
of
bioactive
substances.
The
recent
advancements
in
research
have
significantly
enhanced
our
understanding
polysaccharides,
cellulose-degrading
enzymes,
wide
range
secondary
metabolites.
This
paper
provides
comprehensive
review
the
artificial
cultivation
techniques
chemical
profiling
over
100
metabolites
identified
Horticulturae,
Год журнала:
2024,
Номер
10(6), С. 648 - 648
Опубликована: Июнь 17, 2024
Blossom-end
rot
(BER)
is
a
physiological
disorder
caused
by
calcium
deficiency,
often
paired
with
moisture
stress
and
irregular
traditional
watering
practices.
To
understand
the
biological
mechanism
affecting
incidence
of
BER,
different
tomato
genotypes
were
cultivated
in
sandy
soil
traditionally
irrigated.
Nine
investigated
to
assess
their
susceptibility
rate
varied
from
7.1%
“Voskhod”
57.6%
“Majnat”
genotypes.
This
study
also
comprehensively
analyzed
various
biochemical
parameters
elucidate
correlation
BER
plants.
Our
findings
revealed
range
positively
correlated
incidence,
including
relative
water
content
roots,
number
fruits
per
plant,
vitamin
C
content,
potassium
content.
Parameters
related
fruit
quality,
such
as
titratable
acidity,
peroxidase
firmness
degree,
showed
positive
correlations
incidence.
Conversely,
total
yield
hectare,
chlorophyll
average
plant
height,
demonstrated
strong
negative
suggesting
potential
protective
effects
against
this
disorder.
highlights
that
higher
marketable
yields,
‘Voskhod’
(65
tons/ha),
lower
underscoring
importance
selecting
appropriate
genotype
improving
reducing
blossom-end
fields.
cultivars
high
sensitivity,
‘Chelnok’
(26.3
require
specially
designed
cultivation
management
avoid
production
declines.
Nutraceuticals,
Год журнала:
2025,
Номер
5(1), С. 6 - 6
Опубликована: Фев. 8, 2025
Lyophilized
organ
extracts
from
livestock
such
as
beef
or
elk
are
widely
commercially
proposed
animal-sourced
nutraceuticals.
Such
preparations
contain
blends
of
vitamins
and
nutrients
that
may
be
employed
for
general
specific
dietary
supplementation.
The
first
objective
this
study
was
to
develop
an
optimized
function-oriented
manufacturing
process
stabilized
organ-specific
American
buffalo
(Bison
bison).
second
the
perform
functional
benchmarking
obtained
by
focusing
on
antioxidant
attributes,
which
key
properties
Methodologically,
a
two-step
lyophilization
process,
hard-shell
capsule
formulation,
quality
control
elements
were
adapted
pharmaceutical
technology
practices.
Stabilized
(300
mg
capsules)
derived
spleen,
heart,
liver,
kidneys,
lungs,
thymus
grass-fed
grass-finished
bison
(born
raised
in
tempered
climate
Geneva,
Switzerland).
Functional
performed
using
orthogonal
methods
activity
determination
(TEAC,
FRAP,
H2O2
challenge
assays).
Firstly,
developed
biomass
transformation
enabled
considered
organs
effectively
while
reaching
desired
attributes.
Secondly,
characterization
formulated
revealed
significant
wherein
liver-derived
materials
found
most
potent.
Thirdly,
parameters
(residual
moisture
levels
TEAC)
stable
over
12
months
storage
following
extract
preparation.
Overall,
present
provides
evidence-based
technical/functional
rationale
preparation
lyophilized
included
nutraceutical
preparations.
Agronomy,
Год журнала:
2025,
Номер
15(3), С. 530 - 530
Опубликована: Фев. 21, 2025
Lycopene
(carotenoid)
is
a
natural
pigment
with
strong
antioxidant
properties.
The
taproots
of
red
carrots
(Daucus
carota
L.)
exhibit
coloration
due
to
the
presence
high
levels
lycopene.
However,
candidate
genes
responsible
for
regulating
lycopene
accumulation
in
have
yet
be
identified.
In
this
study,
variations
carotenoid
content
were
assessed
at
five
different
stages
taproot
development.
results
showed
rapid
between
45
and
60
days
after
sowing,
peaking
its
highest
level
by
75
days.
Weighted
Gene
Co-expression
Network
Analysis
(WGCNA)
was
used
construct
co-expression
modules
associated
accumulation.
Notably,
two
identified
(red
mediumpurple3)
exhibited
significant
correlations
content.
A
total
24
differentially
expressed
(DEGs)
enriched
both
Ontology
(GO)
Kyoto
Encyclopedia
Genes
Genomes
(KEGG)
analyses,
one
pathway
gene
only
KEGG
analysis.
Among
these
genes,
photosynthesis
(DCAR_016944
[DcCHL27],
DCAR_021505
[DcFNR2],
DCAR_000568
[DcPSB28],
DCAR_030558
[DcBPG1],
DCAR_030562
[DcBPG1])
(DCAR_013459
[DcCRTISO-1])
highly
connected
hub
genes.
These
six
significantly
up-regulated
when
accumulated
content,
as
findings
contribute
valuable
insights
into
molecular
mechanisms
underlying
modulation
Antioxidants,
Год журнала:
2025,
Номер
14(5), С. 605 - 605
Опубликована: Май 17, 2025
Estrogen
levels
are
the
core
factor
influencing
postmenopausal
osteoporosis
(PMOP).
can
affect
progression
of
PMOP
by
regulating
bone
metabolism,
major
signaling
pathways
related
to
and
modulating
immune
responses.
When
estrogen
decline,
activity
Sirtuins
(SIRTs)
is
reduced.
SIRTs
enzymes
that
function
as
NAD+-dependent
deacetylases.
modulate
osteocyte
function,
sustain
mitochondrial
homeostasis,
relevant
pathways,
thereby
improving
metabolic
imbalances,
reducing
resorption,
promoting
formation.
In
PMOP,
SIRT1,
SIRT3,
SIRT6
primarily
affected.
Oxidative
stress
(OS)
a
crucial
in
it
generates
excessive
reactive
oxygen
species
(ROS)
exacerbate
PMOP.
There
certain
interplay
between
OS.
The
reduced
leads
intensified
OS
accumulation
ROS.
return,
ROS
suppresses
AMPK
pathway
synthesis
NAD+,
which
consequently
diminishes
SIRTs.
Natural
SIRT
activators
natural
antioxidants,
characterized
high
safety,
convenience,
minimal
side
effects,
represent
potential
therapeutic
strategy
for
This
study
aims
investigate
mechanisms
summarize
strategies
assist
improvement
Nutrients,
Год журнала:
2024,
Номер
16(21), С. 3708 - 3708
Опубликована: Окт. 30, 2024
Metabolic
syndrome,
obesity,
and
type
2
diabetes
are
closely
related.
They
characterized
by
chronic
inflammation
oxidative
stress.
Obesity
is
the
most
important
risk
factor
for
metabolic
syndrome
diabetes.
insulin
resistance
elevated
blood
glucose
levels,
among
other
conditions.
These
disorders
contribute
to
development
of
diabetes,
which
can
exacerbate
problems.
