Drug Loading in Chitosan-Based Nanoparticles DOI Creative Commons
Yedi Herdiana, Ellin Febrina, Siti Nurhasanah

и другие.

Pharmaceutics, Год журнала: 2024, Номер 16(8), С. 1043 - 1043

Опубликована: Авг. 6, 2024

Chitosan nanoparticles (CSNPs) are promising vehicles for targeted and controlled drug release. Recognized their biodegradability, biocompatibility, low toxicity, ease of production, CSNPs represent an effective approach to delivery. Encapsulating drugs within (NPs) provides numerous benefits compared free drugs, such as increased bioavailability, minimized toxic side effects, improved delivery, the incorporation additional features like release, imaging agents, combination therapies with multiple drugs. Keys parameters in nanomedicines loading content efficiency. Most current NP systems struggle loading, presenting a significant challenge field. This review summarizes recent research on developing high capacity, focusing various synthesis strategies. It examines CSNP using different materials providing details methods, loadings, encapsulation efficiencies, release profiles, stability, applications Additionally, discusses factors affecting valuable guidelines future CSNPs’ development.

Язык: Английский

Synthesis of Silver Nanoparticles: From Conventional to ‘Modern’ Methods—A Review DOI Open Access

Ngoc Phuong Uyen Nguyen,

Ngoc Tung Dang,

Linh Doan

и другие.

Processes, Год журнала: 2023, Номер 11(9), С. 2617 - 2617

Опубликована: Сен. 2, 2023

Silver nanoparticles, also known as AgNPs, have been extensively researched due to their one-of-a-kind characteristics, including optical, antibacterial, and electrical capabilities. In the era of antibiotics crisis, with an increase in antimicrobial resistance (AMR) a decrease newly developed drugs, AgNPs are potential candidates because substantial activity, limited development, extensive synergistic effect when combined other drugs. The depends on delivery system, compound combination, own properties, such shape size, which heavily influenced by synthesis process. Reduction using chemicals or light, irradiation gamma ray, laser, electron beams microwave biological combination these techniques notable examples AgNP methods. this work, updated methods together strength shortcomings reviewed. Further, factors affecting process discussed. Finally, recent advances challenges considered.

Язык: Английский

Процитировано

99

Current Use of Fenton Reaction in Drugs and Food DOI Creative Commons
Chizumi Abe, Taiki Miyazawa, Teruo Miyazawa

и другие.

Molecules, Год журнала: 2022, Номер 27(17), С. 5451 - 5451

Опубликована: Авг. 25, 2022

Iron is the most abundant mineral in human body and plays essential roles sustaining life, such as transport of oxygen to systemic organs. The Fenton reaction between iron hydrogen peroxide, generating hydroxyl radical, which highly reactive toxic living cells. "Ferroptosis", a programmed cell death closely involved, has recently received much attention. Furthermore, various applications have been reported medical nutritional fields, cancer treatment or sterilization. Here, this review summarizes recent growing interest usefulness its biological relevance through basic practical information reports.

Язык: Английский

Процитировано

74

Silver Nanoparticles: A Comprehensive Review of Synthesis Methods and Chemical and Physical Properties DOI Creative Commons
Hatice Duman, Furkan Eker, Emir Akdaşçi

и другие.

Nanomaterials, Год журнала: 2024, Номер 14(18), С. 1527 - 1527

Опубликована: Сен. 20, 2024

Recently, silver nanoparticles (NPs) have attracted significant attention for being highly desirable nanomaterials in scientific studies as a result of their extraordinary characteristics. They are widely known effective antibacterial agents that capable targeting wide range pathogens. Their distinct optical characteristics, such localized surface plasmon resonance, enlarge utilization, particularly the fields biosensing and imaging. Also, capacity to control charge modify them using biocompatible substances offers improved durability specific interactions with biological systems. Due exceptional stability minimal chemical reactivity, NPs suitable diverse array applications. These produced through chemical, biological, physical processes, each which has advantages disadvantages. Chemical techniques often encounter issues complicated purification, reactive substances, excessive energy usage. However, eco-friendly approaches exist, even though they require longer processing times. A key factor affecting stability, size distribution, purity is synthesis process selected. This review focuses on how essential it choose appropriate method order optimize characteristics use NPs.

Язык: Английский

Процитировано

30

Synthesis, photocatalytic degradation and antibacterial properties of selenium or silver doped zinc oxide nanoparticles: A detailed review DOI Creative Commons
Ikhazuagbe H. Ifijen, Muniratu Maliki,

Bala Anegbe

и другие.

OpenNano, Год журнала: 2022, Номер 8, С. 100082 - 100082

Опубликована: Сен. 10, 2022

Zinc oxide nanoparticles (ZnO NPs) have been the subject of extensive research due to their peculiar physical and chemical properties. Numerous studies used NPs as photocatalytic antibacterial agents because high surface-to-volume ratio, miniature size, antimicrobial activity, semiconducting However, some aforementioned features also exhibit limitations in ZnO NPs. It seems possible circumvent these increase utilization by doping them with silver selenium elements. Therefore, a thorough review use or doped for objectives was conducted this study. Additionally, emphasis placed on synthesis using principally sol-gel, mechanochemical, green techniques. The results showed that considerably improved intrinsic qualities ROS production capability, bandgap, stability, etc., which consequently features. As result, they excelled at photo-catalytic breakdown organic pollutants treatment bacterial illnesses.

Язык: Английский

Процитировано

67

How Nanoparticles Open the Paracellular Route of Biological Barriers: Mechanisms, Applications, and Prospects DOI
Junrong Wu,

Zhenjun Zhu,

Wenjing Liu

и другие.

ACS Nano, Год журнала: 2022, Номер 16(10), С. 15627 - 15652

Опубликована: Сен. 19, 2022

Biological barriers are essential physiological protective systems and obstacles to drug delivery. Nanoparticles (NPs) can access the paracellular route of biological barriers, either causing adverse health impacts on humans or producing therapeutic opportunities. This Review introduces structural functional influences NPs key components that govern route, mainly tight junctions, adherens cytoskeletons. Furthermore, we evaluate their interaction mechanisms address influencing factors determine ability open which provides a better knowledge how in safer more controllable way. Finally, summarize limitations research models methodologies existing field provide future direction. demonstrates in-depth causes for reversible opening destruction integrity generated by NPs; importantly, it contributes insights into design NP-based medications boost delivery efficiency.

Язык: Английский

Процитировано

48

Artificial intelligence in food science and nutrition: a narrative review DOI
Taiki Miyazawa,

Yoichi Hiratsuka,

Masako Toda

и другие.

Nutrition Reviews, Год журнала: 2022, Номер 80(12), С. 2288 - 2300

Опубликована: Апрель 14, 2022

In the late 2010s, artificial intelligence (AI) technologies became complementary to research areas of food science and nutrition. This review aims summarize these technological advances by systematically describing following: use AI in other fields (eg, engineering, pharmacy, medicine); history relation nutrition; currently used agricultural industries; some important applications such as immunity-boosting foods, dietary assessment, gut microbiome profile analysis, toxicity prediction ingredients. These are likely be great demand near future. can provide a starting point for brainstorming generating new nutrition that have yet imagined.

Язык: Английский

Процитировано

42

Interactions between loaded drugs and surfactant molecules in micellar drug delivery systems: A critical review DOI
Urmila Saha, Ranjit De, Bijan Das

и другие.

Journal of Molecular Liquids, Год журнала: 2023, Номер 382, С. 121906 - 121906

Опубликована: Апрель 26, 2023

Язык: Английский

Процитировано

31

Lyotropic liquid crystalline phases: Drug delivery and biomedical applications DOI
Vivek P. Chavda, Sathish Dyawanapelly, Shilpa Dawre

и другие.

International Journal of Pharmaceutics, Год журнала: 2023, Номер 647, С. 123546 - 123546

Опубликована: Окт. 25, 2023

Язык: Английский

Процитировано

25

Combined effect of silica nanoparticles and binary surfactants in enhancing oil recovery: An experimental investigation DOI

Amr Gazem,

Hitendra M. Patel,

Hari Sreenivasan

и другие.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер 702, С. 134980 - 134980

Опубликована: Июль 31, 2024

Язык: Английский

Процитировано

10

Prevention of particle agglomeration in sol–gel synthesis of TiO2 nanoparticles via addition of surfactant DOI

Safira Rachmaniar,

Dhafi Alvian Nugraha,

Dionysius Joseph Djoko Herry Santjojo

и другие.

Journal of Nanoparticle Research, Год журнала: 2024, Номер 26(3)

Опубликована: Фев. 26, 2024

Язык: Английский

Процитировано

9