The Risk of Herpes Zoster in Patients with Depressive Disorders: A German Claims Database Analysis
Infectious Diseases and Therapy,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 22, 2025
Patients
with
depression
were
shown
to
be
at
increased
risk
of
herpes
zoster
(HZ).
However,
an
in-depth
description
as
a
factor
for
HZ,
postherpetic
neuralgia
(PHN),
and
HZ
recurrence
is
lacking.
The
goal
this
study
was
quantify
the
PHN,
in
people
among
depression-related
subgroups
Germany.
Using
health
insurance
claims
data
from
2012
2021
large
German
database,
≥
18
years
old
diagnosed
identified
matched
control
persons
without
using
rolling
cohort
design.
Incidence
rates
(cases
per
1000
person-years
[PYs])
incidence
rate
ratios
(IRRs)
calculated
Poisson
models.
Overall,
1,768,701
controls
depression.
higher
(10.51
cases/1000
PYs)
than
(9.04
PYs).
had
significantly
(IRR
=
1.16;
p
<
0.0001),
PHN
1.22;
0.0001).
IRRs
highest
49
age
group
1.24;
0.0001;
IRR
1.35;
mental
disorder
comorbidities
1.23;
A
diagnosis
associated
recurrence.
People
should
considered
when
developing
vaccination
recommendations.
What
context?
Herpes
(HZ)
painful
disease,
usually
affecting
skin.
more
common
older
adults
chronic
issues,
including
In
Germany,
recommended
aged
60
or
50
certain
comorbidities.
Depression
not
explicitly
mentioned
current
guidelines
although
there
have
been
reports
that
might
increase
risk.
new?
We
analyzed
healthcare
representative
sample
statutory
beneficiaries.
From
these
we
estimated
compared
but
otherwise
similar
characteristics
(age,
sex,
comorbidities).
found
relative
pronounced
younger
groups.
patients
depression,
regardless
type,
severity,
treatment,
HZ.
impact?
Our
results
emphasize
can
all
groups,
making
recommendations
vaccination.
Язык: Английский
How to Prepare Emergency Department for the Next Pandemic? Analysis of Emergency Visits Based on COVID-19 Incidence: A One-Year Multicenter Retrospective Cross-Sectional Study.
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Март 24, 2025
Abstract
Objective:
In
2020,
the
emergence
of
Covid-19,
rapidly
evolves
into
a
global
pandemic.
The
government
has
put
in
place
measures
and
recommendations
to
limit
spread
virus.
Some
studies
have
focused
on
effects
lockdown
social
distancing
Emergency
Department
(ED)
attendance.
Our
hypothesis
is
that
number
visits
vary
with
incidence.
Methods:
We
designed
multicentric,
observational,
retrospective
study
between
May
13,
3,
2021.
All
patients
over
18
years
old
from
8
ED
were
included,
excluding
inter-hospital
transfers.
Demographic
variables,
reasons
for
use,
discharge
diagnosis
destination
extracted
electronic
files.
A
visit
was
considered
covid-like
(CL)
if
one
use
fever,
cough
or
dyspnea.
Reasons
grouped
by
specialty
subgroup
analysis.
compared
entries
according
Covid
incidence
rate
using
Spearman’s
correlation
coefficient
adjusted
governmental
measures.
Results:
237,888
49
49.3%
men
enrolled.
Covid-19
0.22
(p=0.131).
0.24
(p=0.454)
during
lockdown,
0.157
(p=0.467)
unlockdown,
0.832
(p<0.0001)
curfew.
attendance
0.83
CL
0.02
(p=0.880)
non-Covid-like
(NCL)
reasons.
Only
respiratory
miscellaneous
reasons,
where
are
classified
(dyspnea,
fever),
significant
moderate
(respectively
r=0,86,
p<0,0001
r=0,53,
p<0,0001).
diagnoses
infectious
pathologies
relation
r=0,68,
r=0,91,
p<0,0001)
an
increase
hospitalizations
ward
units
(r=0,69,
There
any
intensive
care
units’
admission.
Conclusion:
does
not
highlight
link
NCL
use.
seem
be
good
indicator
predicting
visits.
Язык: Английский
Healthcare visits of the population 50+ in Europe from 2004 to 2022
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 10, 2024
Background
The
COVID-19
pandemic
brought
major
reductions
in
healthcare
visits
Europe.
long-run
consequences
for
systems
depend
on
the
paths
to
post-pandemic
levels,
especially
among
groups
highest
need
of
sustained
care.
Methods
We
used
individual
longitudinal
data
from
27
European
countries
Survey
Health,
Ageing
and
Retirement
Europe,
divided
three
phases:
pre-pandemic
(2004-2019),
(2021),
(2022).
analysed
number
by
gender
over
time
their
correlation
with
age
chronic
conditions
using
a
Bayesian
spatio-temporal
model.
Results
Before
COVID-19,
nominal
rate
varied
two
six
per
year
increased
time.
severely
affected
visits,
an
estimated
reduction
65%
95%
across
countries.
During
older
individuals
those
had
more
than
proportional
visits.
After
pattern
mostly
returned
over-shooting
people
cancer
lag
cardiovascular
diseases.
Conclusion
quick
recovery
most
indicate
that
access
care
stabilised
again.
Yet,
different
trends
vulnerable
show
these
require
timely
action
prevent
long-term
missed
Язык: Английский