The Risk of Herpes Zoster in Patients with Depressive Disorders: A German Claims Database Analysis

Infectious Diseases and Therapy, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Patients with depression were shown to be at increased risk of herpes zoster (HZ). However, an in-depth description as a factor for HZ, postherpetic neuralgia (PHN), and HZ recurrence is lacking. The goal this study was quantify the PHN, in people among depression-related subgroups Germany. Using health insurance claims data from 2012 2021 large German database, ≥ 18 years old diagnosed identified matched control persons without using rolling cohort design. Incidence rates (cases per 1000 person-years [PYs]) incidence rate ratios (IRRs) calculated Poisson models. Overall, 1,768,701 controls depression. higher (10.51 cases/1000 PYs) than (9.04 PYs). had significantly (IRR = 1.16; p < 0.0001), PHN 1.22; 0.0001). IRRs highest 49 age group 1.24; 0.0001; IRR 1.35; mental disorder comorbidities 1.23; A diagnosis associated recurrence. People should considered when developing vaccination recommendations. What context? Herpes (HZ) painful disease, usually affecting skin. more common older adults chronic issues, including In Germany, recommended aged 60 or 50 certain comorbidities. Depression not explicitly mentioned current guidelines although there have been reports that might increase risk. new? We analyzed healthcare representative sample statutory beneficiaries. From these we estimated compared but otherwise similar characteristics (age, sex, comorbidities). found relative pronounced younger groups. patients depression, regardless type, severity, treatment, HZ. impact? Our results emphasize can all groups, making recommendations vaccination.

Language: Английский

How to Prepare Emergency Department for the Next Pandemic? Analysis of Emergency Visits Based on COVID-19 Incidence: A One-Year Multicenter Retrospective Cross-Sectional Study.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Objective: In 2020, the emergence of Covid-19, rapidly evolves into a global pandemic. The government has put in place measures and recommendations to limit spread virus. Some studies have focused on effects lockdown social distancing Emergency Department (ED) attendance. Our hypothesis is that number visits vary with incidence. Methods: We designed multicentric, observational, retrospective study between May 13, 3, 2021. All patients over 18 years old from 8 ED were included, excluding inter-hospital transfers. Demographic variables, reasons for use, discharge diagnosis destination extracted electronic files. A visit was considered covid-like (CL) if one use fever, cough or dyspnea. Reasons grouped by specialty subgroup analysis. compared entries according Covid incidence rate using Spearman’s correlation coefficient adjusted governmental measures. Results: 237,888 49 49.3% men enrolled. Covid-19 0.22 (p=0.131). 0.24 (p=0.454) during lockdown, 0.157 (p=0.467) unlockdown, 0.832 (p<0.0001) curfew. attendance 0.83 CL 0.02 (p=0.880) non-Covid-like (NCL) reasons. Only respiratory miscellaneous reasons, where are classified (dyspnea, fever), significant moderate (respectively r=0,86, p<0,0001 r=0,53, p<0,0001). diagnoses infectious pathologies relation r=0,68, r=0,91, p<0,0001) an increase hospitalizations ward units (r=0,69, There any intensive care units’ admission. Conclusion: does not highlight link NCL use. seem be good indicator predicting visits.

Language: Английский

Healthcare visits of the population 50+ in Europe from 2004 to 2022

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 10, 2024

Background The COVID-19 pandemic brought major reductions in healthcare visits Europe. long-run consequences for systems depend on the paths to post-pandemic levels, especially among groups highest need of sustained care. Methods We used individual longitudinal data from 27 European countries Survey Health, Ageing and Retirement Europe, divided three phases: pre-pandemic (2004-2019), (2021), (2022). analysed number by gender over time their correlation with age chronic conditions using a Bayesian spatio-temporal model. Results Before COVID-19, nominal rate varied two six per year increased time. severely affected visits, an estimated reduction 65% 95% across countries. During older individuals those had more than proportional visits. After pattern mostly returned over-shooting people cancer lag cardiovascular diseases. Conclusion quick recovery most indicate that access care stabilised again. Yet, different trends vulnerable show these require timely action prevent long-term missed

Language: Английский