Quantum Dot Nanomaterials: Empowering Advances in Optoelectronic Devices
Chemical Engineering Journal Advances,
Год журнала:
2025,
Номер
unknown, С. 100704 - 100704
Опубликована: Янв. 1, 2025
Язык: Английский
Synthesis of AgInS2 quantum dots loaded with celastrol for induction of apoptosis and autophagy in hepatocellular carcinoma cells
Discover Oncology,
Год журнала:
2025,
Номер
16(1)
Опубликована: Апрель 16, 2025
Hepatocellular
carcinoma
(HCC)
is
a
predominant
form
of
liver
cancer
and
one
the
leading
causes
cancer-related
death
globally.
Therefore,
there
an
urgent
need
for
innovative
therapeutic
strategies
that
target
molecular
mechanisms
underlying
HCC
progression
metastasis,
aiming
to
improve
treatment
efficacy
patient
survival.
The
natural
product
celastrol
(Cel)
has
demonstrated
inhibitory
effects
in
various
cell
lines.
However,
its
clinical
application
been
hindered
by
high
toxicity
low
safety
threshold.
Metal-free
quantum
dots
(QDs),
AgInS2
(AIS
QDs)
not
only
eliminate
toxic
risks
associated
with
heavy
metals
but
also
exhibit
biocompatibility
biomedical
field.
By
developing
AIS
QD@Cel,
QDs
nano-delivery
system
Cel,
selectivity
Cel
on
were
enhanced.
Fourier-transform
infrared
spectroscopy
(FTIR)
analysis
revealed
can
interact
via
amide
bonds.
encapsulation
rate
reached
27.5%.
QD@Cel
eliminated
293T
enhanced
inhibition
cells
over
10
times.
Furthermore,
western
blotting
flow
cytometry
experiments
showed
promoted
apoptosis
autophagy
signal
pathway.
Finally,
transcriptome
sequencing
effect
regulating
gene
expression
involved
critical
signaling
pathways
are
implicated
cancer.
This
strategy
holds
potential
increase
threshold
applicability
offering
significant
value
patients.
Язык: Английский
Advances in Aptamer-Based Conjugate Recognition Techniques for the Detection of Small Molecules in Food
Xin Deng,
Biao Ma,
Yunfei Gong
и другие.
Foods,
Год журнала:
2024,
Номер
13(11), С. 1749 - 1749
Опубликована: Июнь 2, 2024
Small
molecules
are
significant
risk
factors
for
causing
food
safety
issues,
posing
serious
threats
to
human
health.
Sensitive
screening
hazards
is
beneficial
enhancing
public
security.
However,
traditional
detection
methods
unable
meet
the
requirements
field
of
small
molecules.
Therefore,
it
necessary
develop
applicable
with
high
levels
sensitivity
and
specificity
identify
Aptamers
short−chain
nucleic
acids
that
can
specifically
bind
By
utilizing
aptamers
enhance
performance
recognition
technology,
possible
achieve
selectivity
when
detecting
There
have
been
several
varieties
aptamer
target
techniques
developed
improve
ability
detect
in
recent
years.
This
review
focuses
on
principles
platforms,
classifies
conjugating
between
aptamers,
summarizes
advancements
aptamer−based
conjugate
food,
seeks
provide
emerging
powerful
tools
point−of−care
diagnostics.
Язык: Английский
Introduction to Special Issue “The Self-Assembly and Design of Polyfunctional Nanosystems 3.0”
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(20), С. 10966 - 10966
Опубликована: Окт. 11, 2024
Stimulus-responsive
systems
allowing
for
the
controlled
release
of
drugs
[...].
Язык: Английский