<p>Grip Strength: An Indispensable Biomarker For Older Adults</p>

Clinical Interventions in Aging, Год журнала: 2019, Номер Volume 14, С. 1681 - 1691

Опубликована: Сен. 30, 2019

Grip strength has been proposed as a biomarker. Supporting this proposition, evidence is provided herein that shows grip largely consistent an explanator of concurrent overall strength, upper limb function, bone mineral density, fractures, falls, malnutrition, cognitive impairment, depression, sleep problems, diabetes, multimorbidity, and quality life. Evidence also for predictive link between all-cause disease-specific mortality, future cognition problems associated with hospitalization. Consequently, the routine use can be recommended stand-alone measurement or component small battery measurements identifying older adults at risk poor health status.

Язык: Английский

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Role of gait speed and grip strength in predicting 10-year cognitive decline among community-dwelling older people

BMC Geriatrics, Год журнала: 2019, Номер 19(1)

Опубликована: Июль 5, 2019

The gait speed and handgrip strength represented the core determinants of physical frailty sarcopenia, which were reported to be associated with cognitive impairment decline. Different measures might differentially affect changes, such as higher-level change global This study examined differential associations 10-year changes among community-dwelling older people.Participants aged 60 years over living in community invited for study. Gait classified into 5 groups based on quintiles at baseline. Cognitive functions assessed using Mini-Mental State Examination (MMSE) Digit Symbol Substitution Test (DSST) every 2 from baseline a period 10 years. Linear mixed effects models used determine role prediction by adjusting covariates, including age, gender, education, depressive symptoms, marital status, smoking instrumental activities daily life (IADL), Charlson Comorbidity Index (CCI), body mass index (BMI) baseline.A total 1096 participants enrolled mean age was 69.4 ± 5.8 50.9% male. slowest group showed significantly greater decline DSST scores than highest (estimate = 0.28 P 0.003), but not MMSE 0.05 0.078). lowest 0.06 0.039) two 0.20 0.033 fourth quintile; estimate 0.040 quintile) follow-up.A slow could predict DSST, low addition DSST. Thus both are lined there may different mechanisms between brain functions.

Язык: Английский

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Diagnosing sarcopenia: Functional perspectives and a new algorithm from the ISarcoPRM

Journal of Rehabilitation Medicine, Год журнала: 2021, Номер 53(6), С. jrm00209 - jrm00209

Опубликована: Янв. 1, 2021

Sarcopenia is an important public health problem, characterized by age-related loss of muscle mass and function. It a precursor physical frailty, mobility limitation, premature death. Muscle mainly due to the type II fibres, progressive motor neurones thought be primary underlying factor. Anterior thigh muscles undergo atrophy earlier, anterior function may therefore antecedent finding. The aim this review provide in-depth (and holistic) neuromusculoskeletal approach sarcopenia. In addition, under umbrella International Society Physical Rehabilitation Medicine (ISPRM), novel diagnostic algorithm proposed, developed with consensus experts in special interest group on sarcopenia (ISarcoPRM). advantages over others are: caution concerning disorders related renin-angiotensin system at case finding stage; emphasis loss; incorporation ultrasound for first time measure muscle; addition chair stand test as power/performance assess Refining testing remains priority future research.

Язык: Английский

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The impact of leisure activities on older adults’ cognitive function, physical function, and mental health

PLoS ONE, Год журнала: 2019, Номер 14(11), С. e0225006 - e0225006

Опубликована: Ноя. 8, 2019

Engagement in leisure activities has been claimed to be highly beneficial the elderly. Practicing such is supposed help older adults preserve cognitive function, physical and mental health, thus contribute successful aging. We used structural equation modeling (SEM) analyze impact of on these constructs a large sample Japanese (N = 809; age range 72–74). The model exhibited an excellent fit (CFI 1); engaging was positively associated with all three aging indicators. These findings corroborate previous research carried out Western countries extend its validity population Eastern adults. Albeit correlational nature, results suggest that active engagement can maintain cognitive, physical, health. Future will clarify whether there causal relationship between

Язык: Английский

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Manual Dexterity and Aging: A Pilot Study Disentangling Sensorimotor From Cognitive Decline

Frontiers in Neurology, Год журнала: 2018, Номер 9

Опубликована: Окт. 29, 2018

Manual dexterity measures can be useful for early detection of age-related functional decline and prediction cognitive decline. However, what aspects sensorimotor function to assess remains unclear. markers should able separate impairments related from those healthy aging. In this pilot study, we aimed compare manual components in patients diagnosed with (mean age: 84 years, N=11) age comparable cognitively intact elderly subjects 78 N=11). order due aging deficits also included two groups young adults 26 N=10) middle-aged 41 N=8). A comprehensive quantitative evaluation was performed using three tasks: (i) visuomotor force tracking, (ii) isochronous single finger tapping auditory cues, (iii) multi-finger tapping. Results showed a highly significant increase tracking error increasing age. Subjects had increased variability reduced ability select the correct fingers task compared subjects. Elderly prolonged release independence movements adults. Two different patterns impaired were found: one another Increased decreased effector (finger) found only contrast, precision during This suggests that tasks requiring updating performance, accordance (temporal or spatial) rules maintained short-term memory, are particularly affected Conversely, online matching motor output sensory cues by age, not status. Remarkably, no detected clinical scales hand function. may have consequences development

Язык: Английский

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Handgrip strength and risk of cognitive outcomes: new prospective study and meta-analysis of 16 observational cohort studies

GeroScience, Год журнала: 2022, Номер 44(4), С. 2007 - 2024

Опубликована: Янв. 10, 2022

Abstract Handgrip strength (HGS), a measure of muscular strength, might be risk indicator for cognitive functioning, but the evidence is not consistent. Using new prospective study and meta-analysis published observational cohort studies, we aimed to evaluate associations HGS with poor outcomes including impairment, dementia Alzheimer’s disease (AD). measured using Martin-Balloon-Vigorimeter, was assessed at baseline in population-based sample 852 men women good function Kuopio Ischemic Heart Disease cohort. Hazard ratios (HRs) 95% confidence intervals (CIs) were estimated outcomes. Relevant studies sought MEDLINE, Embase Web Science from inception until October 2021 pooled random effects meta-analysis. During median follow-up 16.6 years, 229 cases recorded. Comparing extreme tertiles HGS, multivariable adjusted HR (95% CI) dementia, AD vascular 0.77 (0.55–1.07), 0.75 (0.52–1.10) 0.49 (0.16–1.48), respectively. In 16 (including current study) comprising 180,920 participants, relative risks CIs) comparing top vs bottom thirds levels as follows: 0.58 (0.52–0.65) impairment; 0.37 (0.07–1.85) decline; 0.73 (0.62–0.86) dementia; 0.68 (0.53–0.87) AD; 0.48 (0.32–0.73) dementia. GRADE quality ranged low very low. Meta-analysis aggregate data suggests that may such AD. Systematic review registration: PROSPERO 2021: CRD42021237750.

Язык: Английский

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Hand dexterity, not handgrip strength, is associated with executive function in Japanese community-dwelling older adults: a cross-sectional study

BMC Geriatrics, Год журнала: 2018, Номер 18(1)

Опубликована: Авг. 24, 2018

An association between handgrip strength, hand dexterity and global cognition is suggested; however, it unclear whether both motor functions are associated with executive function, which important for performing daily activities. Understanding this will help identify risk factors impairment of function in late adulthood. We aim to investigate the relationship strength physically mentally healthy community-dwelling older adults.Three hundred twenty-six adults (287 women, mean age ± SD, 70.1 5.6) underwent tests using a dynamometer Purdue Pegboard Test (PPT), respectively. Executive was evaluated Trail Making (TMT)-A, TMT-B Digit symbol; assessed Mini-Mental State Examination (MMSE).Age-group differences showed that younger groups (60-64, 65-69 70-74) had significant better PPT performance than oldest group (75 older), whereas no were observed strength. Multiple regression analysis adjusted potential covariates, including MMSE scores, TMT-A, TMT-B, symbol significantly scores; variables strength.Hand vulnerable effects aging and, contrary strongly associates independent cognition. Our results suggest assessing may individuals at higher among high-functioning adults.

Язык: Английский

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Relationship Between Physical Performance and Mild Cognitive Impairment in Chinese Community-Dwelling Older Adults

Clinical Interventions in Aging, Год журнала: 2021, Номер Volume 16, С. 119 - 127

Опубликована: Янв. 1, 2021

This study aimed to examine the relationship between physical performance and mild cognitive impairment (MCI) in Chinese older adults.The sample comprised 956 relatively healthy aged ≥65 years old community-dwelling participants (mean age, 72.56 ± 5.43 years; 56.8% female), which did not include those with dementia, severe impairment, mental illness etc. The Mini-Mental State Examination (MMSE) Instrumental Activities of Daily Living (IADL) scale were used for initial classification patients MCI. Physical was measured via hand grip, Timed Up Go Test (TUGT), 4-m walking speed.The (grip strength, TUGT, speed) correlated grip strength [odds ratio (OR) = 0.96, 95% confidence interval (CI) 0.93-0.99] speed (OR 0.25, CI 0.10-0.64) negatively MCI, while TUGT 1.08, 1.03-1.13) MCI positively.The Further analysis showed that associated overall cognition, time orientation, recall, language, cognition various domains, except recall.

Язык: Английский

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Hand grip strength and quality of life among adults aged 50–90 years from South West Poland

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 6, 2025

With advancing age, progressive loss of muscle strength, as assessed by hand grip may result in a poorer health-related quality life. The aim this study is to determine the associations strength with life among people aged 50–90 years from South West Poland. group comprised 1 446 people, including 351 men and 095 women, between 50 90 years. WHOQoL-BREF questionnaire was used assess Hand dominant measured. general assessment shows significant relationship strength. Two domains life: social environmental also significantly differentiate As number points given increases, increases. Among men, domain stronger compared women. related older adults, especially domains. results our suggest that measures need be taken improve skeletal muscles which might their

Язык: Английский

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Oral health implications in Parkinson’s disease

npj Parkinson s Disease, Год журнала: 2025, Номер 11(1)

Опубликована: Апрель 11, 2025

To assist patients in maintaining oral health with Parkinson's disease (PD), this review aims to search the literature on aspects related PD patients. In contrast other research, we included involvement of microbes patients' poor health. Finally, conclude that, comparison healthy individuals, have poorer and a higher incidence ailments.

Язык: Английский

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