Microchemical Journal, Год журнала: 2025, Номер unknown, С. 114118 - 114118
Опубликована: Июнь 1, 2025
Язык: Английский
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(18), С. 9938 - 9938
Опубликована: Сен. 14, 2024
The increasing interest in bacteriophage technology has prompted its novel applications to treat different medical conditions, most interestingly cancer. Due their high specificity, manipulability, nontoxicity, and nanosize nature, phages are promising carriers targeted therapy cancer immunotherapy. This approach is particularly timely, as current challenges research include damage healthy cells, inefficiency targeting, obstruction by biological barriers, drug resistance. Some cancers being kept at the forefront of phage research, such colorectal HCC, while others like lymphoma, cervical cancer, myeloma have not been retouched a decade. Common mechanisms immunogenic antigen display on coats use transporters carry drugs, genes, other molecules. To date, popular treatments tested gene phage-based vaccines using M13 λ phage, with some having advanced human clinical trials. results from these studies promising, but limitations therapies reticuloendothelial system clearance or diffusion must be addressed. Before for can successfully used oncology practice, more in-depth support local governments required.
Язык: Английский
Процитировано
3
Langmuir, Год журнала: 2024, Номер unknown
Опубликована: Сен. 28, 2024
In this work, we report a study examining how different salt concentrations affect the structure and electrochemical performance of two Co
Язык: Английский
Процитировано
3
Methods in pharmacology and toxicology, Год журнала: 2025, Номер unknown, С. 105 - 123
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Methods in cell biology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Biomedicines, Год журнала: 2025, Номер 13(5), С. 1202 - 1202
Опубликована: Май 15, 2025
Bacteriophages are a unique and fascinating group of viruses, known for their highly specific ability to infect replicate within bacterial cells. While potential as antibacterial agents has been recognized decades, recent research revealed complex interactions between phages the human immune system, offering new insights into role in modulation. New evidence reveals dynamic intricate relationship cytokines, suggesting regulate inflammation, tolerance, host-pathogen interaction. Herein, we review how affect production cytokines behavior cells indirectly by lysis bacterium or directly on mammalian Phages have shown induce both pro- anti-inflammatory responses recently, they explored personalized immunotherapy, cancer microbiome modulation, which focus this review. Several challenges remain despite significant progress, including practical obstructions related endotoxins along with host variability regulatory issues. Nevertheless, bacteriophages modulate makes them attractive candidates future precision medicine.
Язык: Английский
Процитировано
0
Microchemical Journal, Год журнала: 2025, Номер unknown, С. 114118 - 114118
Опубликована: Июнь 1, 2025
Язык: Английский
Процитировано
0