Effect of leisure activities on cognitive and memory function in older adults: A systematic review and meta-analysis of randomized controlled trials

Journal of Clinical Neuroscience, Год журнала: 2025, Номер 133, С. 111055 - 111055

Опубликована: Янв. 21, 2025

Язык: Английский

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Digital Marker for Early Screening of Mild Cognitive Impairment Through Hand and Eye Movement Analysis in Virtual Reality Using Machine Learning: First Validation Study

Journal of Medical Internet Research, Год журнала: 2023, Номер 25, С. e48093 - e48093

Опубликована: Окт. 20, 2023

Background With the global rise in Alzheimer disease (AD), early screening for mild cognitive impairment (MCI), which is a preclinical stage of AD, paramount importance. Although biomarkers such as cerebrospinal fluid amyloid level and magnetic resonance imaging have been studied, they limitations, high cost invasiveness. Digital markers to assess by analyzing behavioral data collected from digital devices daily life can be new alternative. In this context, we developed “virtual kiosk test” MCI when using virtual environment. Objective We aimed investigate key features test that could distinguish patients with healthy controls statistical significance. Also, focused on developing machine learning model capable based these features. Methods A total 51 participants comprising 20 31 were recruited 2 neurologists university hospital. The performed test—developed our group—where recorded various hand eye movements. Based time series data, computed following 4 features: movement speed, proportion fixation duration, completion, number errors. To compare between MCI, independent-samples 2-tailed t tests used. Additionally, used train validate controls. Results test, all showed statistically significant differences Compared controls, had slower speed (t49=3.45; P=.004), lower duration (t49=2.69; P=.04), longer completion (t49=–3.44; greater errors (t49=–3.77; P=.001). All then support vector MCI. Our achieved 93.3% accuracy, 100% sensitivity, 83.3% specificity, 90% precision, 94.7% F1-score. Conclusions research preliminarily suggests movements holds potential marker contrast conventional biomarkers, reality advantageous it collect ecologically valid at an affordable short period (5-15 minutes), making suitable means call further studies confirm reliability validity approach.

Язык: Английский

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A comprehensive study on unraveling the advances of immersive technologies (VR/AR/MR/XR) in the healthcare sector during the COVID-19: Challenges and solutions

Heliyon, Год журнала: 2024, Номер 10(15), С. e35037 - e35037

Опубликована: Июль 23, 2024

The current COVID-19 pandemic has affected almost every aspect of life but its impact on the healthcare landscape is conspicuously adverse. However, digital technologies played a significant contribution in coping with challenges spawned by this pandemic. In list applied technologies, role immersive battling notice-worthy. Immersive consisting virtual reality (VR), augmented (AR), mixed (MR), extended (XR), metaverse, gamification, etc. have shown enormous market growth within system, particularly emergence pandemics. These supplemented interactivity, experience, 3D modeling, touching sensory elements, simulation, and feedback mechanisms to tackle disease systems. Keeping view applicability significance technological advancement, major aim study identify highlight concerning handling setup. domain for different purposes such as medical education, training, proctoring, online surgeries, stress management, social distancing, physical fitness, drug manufacturing designing, cognitive rehabilitation highlighted. A comprehensive in-depth analysis collected studies been performed understand research work future directions. state-of-the-artwork presented discuss various issues involving adoption area. Furthermore, solutions these emerging provided based an extensive literature study. results show that considerable potential provide massive support stakeholders system during situation

Язык: Английский

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Global research hotspots and trends on robotic surgery in obstetrics and gynecology: a bibliometric analysis based on VOSviewer

Frontiers in Surgery, Год журнала: 2024, Номер 11

Опубликована: Фев. 9, 2024

Objective Over the last two decades, quantity of papers published in relation to robotic surgery obstetrics and gynecology has continued grow globally. However, no bibliometric analysis based on VOSviewer been performed evaluate past present global research field. In this study, we aimed analyze characteristics reveal hotspots trends Methods The Web Science Core Collection was searched for scientific between January 1, 1998 December 31, 2023. Bibliometric metadata each selected paper extracted analysis. results were visualized by (version 1.6.18). Results A total 1,430 met inclusion criteria. United States had highest link strengths contributed most ( n = 793). Mayo Clinic produced largest number 85), Professor Pedro T Ramirez 36). citations ranged from 0 295 with a sum 29,103. Journal Minimally Invasive Gynecology relevant 252). Keywords classified into six clusters co-occurrence data, which cluster 4 6 more main keywords average publication year. Conclusions This is first VOSviewer-based gynecology. leading country, productive journal Scientists institutions around world should push their boundaries bring about deep collaboration. topic always use treatment gynecologic malignancies. More randomized controlled trials need be conducted compare surgical outcomes other approaches. Robotic sacrocolpopexy pelvic organ prolapse become new hotspot, sentinel lymph node detection malignancies are potential directions future research.

Язык: Английский

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The use of co-words to analyse the conceptual structure of the application of VR and AR in autistic students

Journal of Enabling Technologies, Год журнала: 2025, Номер 19(1), С. 15 - 35

Опубликована: Фев. 11, 2025

Purpose The objective of the research is to conduct a comprehensive analysis conceptual structure underlying global trends in utilization VR/AR for learning purposes among autistic children and adolescents. Design/methodology/approach With sample 57 documents obtained from different databases period 2010–2022, scientific mapping was developed using bibliometrix library designed R. Findings It has been found that there are three main lines work. first with emotion recognition theory mind. Another line focused on “young children” works visual attention, simulation play social communication. third adolescents subthemes such as executive function, skills environments. Originality/value allows authors design activities those areas where use successful. In this way, future implementation these tools classroom encouraged.

Язык: Английский

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Impact of cognitive rehabilitation interventions on memory improvement in patients after stroke: A systematic review

World Journal of Methodology, Год журнала: 2025, Номер 15(3)

Опубликована: Март 6, 2025

BACKGROUND Cognitive impairment is a major cause of disability in patients who have suffered from stroke, and cognitive rehabilitation interventions show promise for improving memory. AIM To examine the effectiveness virtual reality (VR) non-VR (NVR) techniques memory after stroke. METHODS An extensive thorough search was executed across five pertinent electronic databases: Cumulative Index to Nursing Allied Health Literature; MEDLINE (PubMed); Scopus; ProQuest Central; Google Scholar. This systematic review conducted following preferred reporting items reviews meta-analyses guideline. Studies that recruited participants experienced utilized interventions, published last 10 years were included review. RESULTS Thirty studies met inclusion criteria. VR significantly improved function (mean difference: 4.2 ± 1.3, P < 0.05), whereas NVR (including training, music, exercise) moderately Compared with traditional methods, technology-driven approaches particularly beneficial enhancing daily tasks. CONCLUSION are post-stroke recovery, providing enhanced immersive experiences. Both hold transformative potential rehabilitation.

Язык: Английский

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Research Hotspots and Trends of Virtual Reality Intervention for Stroke: A Bibliometric Analysis (Preprint)

JMIR Serious Games, Год журнала: 2025, Номер 13, С. e65993 - e65993

Опубликована: Март 13, 2025

Virtual reality (VR) is a rapidly developing technology that has gained significant traction in the treatment and rehabilitation of individuals with stroke. Research on VR-based stroke garnered increasing attention. The aim this study to present bibliometric analysis VR for studies identify application status, research hotspots, emerging trends guide future scientific research. We included reviews topic from 1999 2023 were retrieved Web Science Core Collection database. Citespace 6.3.1 VOSviewer 1.6.20 software was used visual publications, institutions, authors, journals, citations, Scimago Graphica geographic visualization published countries or regions. Our analyzed 1171 papers between 2023, revealing gradual increase annual publications over past 2 decades, peaking at 154 2022. North America Western Europe identified as major contributors, input their researchers, publications. Journal NeuroEngineering Rehabilitation emerged leading journal field, while Calabrò Rocco Salvatore recognized most prolific author, focusing neurophysiological impacts patients Keywords notable citation bursts, such "environment," "trial," "arm," "motor learning," highlighted core themes domain. provides valuable insights into current hotspots rehabilitation. Current primarily focuses evaluating effectiveness improving upper limb function balance Future directions are shifting towards integrating techniques, physiotherapy occupational therapy, advancements continue garner

Язык: Английский

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Digital technologies in rehabilitation of patients with cognitive impairment and dementia

Vestnik nevrologii psihiatrii i nejrohirurgii (Bulletin of Neurology Psychiatry and Neurosurgery), Год журнала: 2025, Номер 2, С. 141 - 152

Опубликована: Фев. 15, 2025

Cognitive impairment is a prevalent and socially significant issue affecting large portion of the human population. Traditional approaches to cognitive rehabilitation exhibit inconsistent limited effectiveness, especially considering rapid digitalization healthcare. This paper explores potential digital technologies in individuals with dementia assesses their effectiveness future development prospects. Computer programs can standardize automate training, offering structured delivery system. Virtual reality enable enhancement skills by simulating realistic scenarios virtual environment. Additionally, chatbots artificial intelligence offer personalized, adaptive approaches, while telemedicine addresses challenge providing access specialized neuropsychological care. Existing research demonstrates interventions rehabilitation, evidence supporting several tools. However, there dearth studies this area, integration these into clinical practice faces challenges, including sustaining patient clinician engagement, integration, rigorous validation technologies. Recent advancements reality, robotics, are undergoing active testing, application impairments holds promise for near future.

Язык: Английский

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From virtual to reality: innovative practices of digital twins in tumor therapy

Journal of Translational Medicine, Год журнала: 2025, Номер 23(1)

Опубликована: Март 19, 2025

As global cancer incidence and mortality rise, digital twin technology in precision medicine offers new opportunities for treatment. This study aims to systematically analyze the current applications, research trends, challenges of tumor therapy, while exploring future directions. Relevant literature up 2024 was retrieved from PubMed, Web Science, other databases. Data visualization performed using R VOSviewer software. The analysis includes initiation funding models, distribution, sample size analysis, data processing artificial intelligence applications. Furthermore, investigates specific applications effectiveness diagnosis, treatment decision-making, prognosis prediction, personalized management. Since 2020, on oncology has surged, with significant contributions United States, Germany, Switzerland, China. Funding primarily comes government agencies, particularly National Institutes Health U.S. Sample reveals that large-sample studies have greater clinical reliability, small-sample emphasize validation. In integration medical imaging, multi-omics data, AI algorithms is key. By combining multimodal dynamic modeling, accuracy models been significantly improved. However, different types still faces related tool interoperability limited standardization. Specific shown advantages surgical planning. Digital holds substantial promise therapy by optimizing plans through integrated modeling. factors such as language restrictions, potential selection bias, relatively small number published this emerging field, which may affect comprehensiveness generalizability our findings. Moreover, issues heterogeneity, technical integration, privacy ethics continue impede its broader application. Future should promote international collaboration, establish unified interdisciplinary standards, strengthen ethical regulations accelerate translation

Язык: Английский

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Cognitive Training With Head-Mounted Display Virtual Reality in Neurorehabilitation: Pilot Randomized Controlled Trial

JMIR Serious Games, Год журнала: 2023, Номер 11, С. e45816 - e45816

Опубликована: Июнь 24, 2023

Neurological rehabilitation is technologically evolving rapidly, resulting in new treatments for patients. Stroke, one of the most prevalent conditions neurorehabilitation, has been a particular focus recent years. However, patients often need help with physical and cognitive constraints, whereby domain neurorehabilitation does not exploit existing potential. Usually, performed pen paper or on computer, which leads to limitations preparation activities daily living. Technologies such as virtual reality (VR) can bridge this gap.This pilot study investigated use immersive VR undergoing inpatient neurorehabilitation. The goal was determine difference effectiveness between serious game that combines everyday paradigms conventional computerized training. We hypothesized superiority regarding abilities patient-reported outcomes well transfer life.We recruited 42 acute brain affection from German clinic care Mini Mental Status Test score >20 participate randomized controlled trial. Participants were randomly assigned 2 groups, 1 receiving experimental treatment (n=21). training consisted life scenarios, example, kitchen, focusing treating executive functions planning problem-solving. control group (n=21) received Each participant minimum 18 sessions their respective group. Patients tested status, subjective health, quality before after intervention (Alters-Konzentrations-Test, Wechsler Memory Scale-Revised, Trail Making A B, Tower London-German version, Short Form 36, European Quality Life 5 Dimensions visual analog scale, Fragebogen zur Erfassung der Performance VR).Repeated-measures ANOVA revealed several significant main effects tests: version (P=.046), (P=.01), Scale-Revised (P=.006). post hoc tests showed improvement planning, control, problem-solving domains (P=.046, Bonferroni P=.02). In contrast, no t0 t1 detected (all P>.05). Furthermore, nonsignificant trend observed speed (P=.09, P=.02).The results trial had greater than standard experiencing stroke some . These findings support further incorporating living other neurological disorders involving dysfunction.Federal Registry Clinical Trials Germany (DRKS) DRKS00023605; https://drks.de/search/de/trial/DRKS00023605.

Язык: Английский

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