Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care (Preprint) DOI
Clare E. Palmer,

Eliot Marshall,

Edward Millgate

и другие.

Опубликована: Ноя. 28, 2024

BACKGROUND Escalating mental health demand exceeds existing clinical capacity, necessitating scalable digital solutions. However, engagement remains challenging. Conversational agents can enhance by making programs more interactive and personalized, but they have not been widely adopted. This study evaluated a program for anxiety in comparison to external comparators. The used an artificial intelligence (AI)–driven conversational agent deliver clinician-written content via machine learning, with clinician oversight user support. OBJECTIVE aims evaluate the engagement, effectiveness, safety of this structured, evidence-based human support mild, moderate, severe generalized anxiety. Statistical analyses sought determine whether reduced than propensity-matched waiting control was statistically noninferior real-world, face-to-face typed cognitive behavioral therapy (CBT). METHODS Prospective participants (N=299) were recruited from National Health Service (NHS) or social media United Kingdom given access up 9 weeks (study conducted October 2023 May 2024). End points collected before, during, after program, as well at 1-month follow-up. External comparator groups created through propensity matching sample NHS Talking Therapies (NHS TT) data ieso Digital (typed CBT) Dorset HealthCare (DHC) University Foundation Trust (face-to-face CBT). Superiority noninferiority compare symptom reduction (change on 7-item Generalized Anxiety Disorder Scale [GAD-7]) between group groups. included support, time spent per participant calculated. RESULTS Participants median 6 hours over 53 days, 232 299 (77.6%) engaged (ie, completing 2 14 days). There large, clinically meaningful symptoms (per-protocol [PP; n=169]: mean GAD-7 change –7.4, d=1.6; intention-to-treat [ITT; n= 99]: –5.4, d=1.1). PP effect superior (d=1.3) CBT (<i>P</i>&lt;.001) (<i>P</i>&lt;.001). Similarly, ITT sample, showed superiority (d=0.8) (<i>P</i>=.002), approaching significance (<i>P</i>=.06). Effects sustained Clinicians overseeing 1.6 (range 31-200 minutes) sessions participant. CONCLUSIONS By combining AI achieved outcomes comparable human-delivered care, while significantly reducing required 8 times compared global care estimates. These findings highlight potential technology scale address unmet needs, ultimately impact quality life reduce economic burden globally. CLINICALTRIAL ISRCTN Registry ISRCTN52546704; http://www.isrctn.com/ISRCTN52546704

Язык: Английский

A New Research Model for Artificial Intelligence–Based Well-Being Chatbot Engagement: Survey Study DOI Creative Commons
Yanrong Yang, Jorge Tavares, Tiago Oliveira

и другие.

JMIR Human Factors, Год журнала: 2024, Номер 11, С. e59908 - e59908

Опубликована: Ноя. 11, 2024

Artificial intelligence (AI)-based chatbots have emerged as potential tools to assist individuals in reducing anxiety and supporting well-being.

Язык: Английский

Процитировано

1

The LvL UP Trial: Protocol for a Sequential, Multiple Assignment, Randomized Controlled Trial to Assess the Effectiveness of a Blended Mobile Lifestyle Intervention DOI Open Access
Óscar Castro, Jacqueline L. Mair, Shenglin Zheng

и другие.

Опубликована: Авг. 16, 2024

Background: Blended mobile health (mHealth) interventions – combining self-guided and human support components could play a major role in preventing non-communicable diseases (NCDs) common mental disorders (CMDs). This protocol paper describes sequential, multiple assignment, randomised trial aimed at (i) evaluating the effectiveness cost-effectiveness of LvL UP, an mHealth lifestyle intervention for prevention NCDs CMDs, (ii) establishing optimal blended approach UP that balances effective personalised with scalability.Methods: is 6-month holistic targeting physical activity, diet, emotional regulation. In this trial, young middle-aged Singaporean adults risk developing or CMDs will be randomly allocated to one two initial conditions (‘LvL UP’ ‘comparison’). After 4 weeks, participants categorised as non-responders from group re-randomised into second-stage conditions: continuing (LvL UP) additional motivational interviewing (MI) sessions by trained coaches + adaptive MI). The primary outcome well-being (via Warwick-Edinburgh Mental Wellbeing Scale). Secondary outcomes include anthropometric measurements, resting blood pressure, metabolic profile, status, behaviours (physical diet), work productivity, healthcare utilisation. Outcomes measured baseline, 6 months (post-intervention), 12 (follow-up).Discussion: addition proposed study design contribute increasing evidence on how introduce maximise their while remaining scalable.Trial registration: Pilot was prospectively registered ClinicalTrials.gov (NCT06360029) 7 April 2024.

Язык: Английский

Процитировано

0

Human-centred design (HCD) and digital transformation of mental health services: A narrative review and personal view from the United Kingdom (Preprint) DOI
William Fleming, Adam Coutts,

Diane Pochard

и другие.

Опубликована: Сен. 2, 2024

UNSTRUCTURED Mental health services face a multitude of challenges, such as increasing demand, underfunding and limited workforce capacity. The accelerated digital transformation public is positioned by government, private sector some academic researchers the solution. Alongside, human-centred design (HCD) has emerged guiding paradigm for this to ensure user needs are met. We define what HCD are, how they implemented in UK policy context, their role within evolving delivery mental services. Our co-author’s involvement these policies over past five years provides unique insights into decision-making process story. review promises, pitfalls ongoing challenges identified across multi-disciplinary literature. Finally, we propose future research questions options that designed delivered meet population.

Язык: Английский

Процитировано

0

Determinants of Dropout from a Virtual-Agent Based App for Insomnia Management: An Analysis in a Longitudinal, Self-Selected Sample of Users with Insomnia Symptoms (Preprint) DOI Creative Commons
M. Montserrat Sánchez-Ortuño, Florian Pécune, Julien Coelho

и другие.

JMIR Mental Health, Год журнала: 2024, Номер 12, С. e51022 - e51022

Опубликована: Окт. 3, 2024

Fully automated digital interventions delivered via smartphone apps have proven efficacious for a wide variety of mental health outcomes. An important aspect is that they are accessible at low cost, thereby increasing their potential public impact and reducing disparities. However, major challenge to successful implementation the phenomenon users dropping out early. The purpose this study was pinpoint factors influencing early dropout in sample self-selected virtual agent (VA)-based behavioral intervention managing insomnia, named KANOPEE, which freely available France. From January 2021 December 2022, 9657 individuals, aged 18 years or older, who downloaded completed KANOPEE screening interview had either subclinical clinical insomnia symptoms, 4295 (44.5%) dropped (ie, did not return app continue filling subsequent assessments). primary outcome binary variable: having after completing assessment (early dropout) all treatment phases (n=551). Multivariable logistic regression analysis used identify predictors among set sociodemographic, clinical, sleep diary variables, users' perceptions program, collected during interview. mean age 47.95 (SD 15.21) years. Of those treatment, 65.1% (3153/4846) were women 34.9% (1693/4846) men. Younger (adjusted odds ratio [AOR] 0.98, 95% CI 0.97-0.99), lower education level (compared middle school; high school: AOR 0.56, 0.35-0.90; bachelor's degree: 0.35, 0.23-0.52; master's degree higher: 0.22-0.55), poorer nocturnal (sleep efficiency: 0.64, 0.42-0.96; number awakenings: 1.13, 1.04-1.23), more severe depression symptoms (AOR 1.12, 1.04-1.21) significant out. When measures included model, perceived benevolence credibility VA decreased 0.91, 0.85-0.97). As traditional face-to-face cognitive therapy presence plays an role dropout. This variable represents target address increase engagement with fully management programs. Furthermore, our results support contention can provide relevant user stimulation will eventually pay terms engagement.

Язык: Английский

Процитировано

0

A New Research Model for Artificial Intelligence–Based Well-Being Chatbot Engagement: Survey Study (Preprint) DOI
Yanrong Yang, Jorge Tavares, Tiago Oliveira

и другие.

Опубликована: Апрель 27, 2024

BACKGROUND Artificial intelligence (AI)–based chatbots have emerged as potential tools to assist individuals in reducing anxiety and supporting well-being. OBJECTIVE This study aimed identify the factors that impact individuals’ intention engage their engagement behavior with AI-based well-being by using a novel research model enhance service levels, thereby improving user experience mental health intervention effectiveness. METHODS We conducted web-based questionnaire survey of adult users China via social media. Our collected demographic data, well range measures assess relevant theoretical factors. Finally, 256 valid responses were obtained. The newly applied was validated through partial least squares structural equation modeling approach. RESULTS explained 62.8% (<i>R</i><sup>2</sup>) variance 74% behavior. Affect (β=.201; <i>P=</i>.002), (β=.184; <i>P=</i>.007), compatibility (β=.149; <i>P=</i>.03) statistically significant for engage. Habit (β=.154; <i>P=</i>.01), trust (β=.253; <i>P&lt;</i>.001), (β=.464; <i>P&lt;</i>.001) CONCLUSIONS new extended provides basis studying users’ chatbot highlights practical points developers chatbots. It also importance create an emotional connection users.

Язык: Английский

Процитировано

0

Acceptability and Feasibility of the English Version of Elevida, a Self-Guided Online Fatigue Intervention for People With Multiple Sclerosis DOI Open Access
Jo Lane, Carmel Poyser, Yixuan Zhao

и другие.

International Journal of MS Care, Год журнала: 2024, Номер 26(Q4), С. 347 - 354

Опубликована: Дек. 9, 2024

Fatigue is common in multiple sclerosis (MS); it significantly impairs quality of life, and treatment options are limited. A randomized controlled trial Elevida, a self-guided, online German fatigue intervention, showed significant benefit. We tested an English version Elevida with people MS Australia. Participants were volunteers who self-reported at least mild (≥ 43 on the Scale for Motor Cognitive Functions scale), some mobility (Expanded Disability Status < 8), no or cognitive difficulties (≤ 32 Multiple Sclerosis Neuropsychological Questionnaire). completed 9-week program, commenting rating its acceptability. The Chalder was baseline, end-of-program, 2 months later. undertook qualitative (thematic analysis) quantitative (before/after differences, using paired t test) analyses. Thirty-eight expressed interest study; 26 eligible; 20 began study. Fifteen participants (75%) program (mean [SD]: 58.9 [10.5] years age, 67% women, 9 relapsing MS, 6 progressive MS). Over 90% completing rated acceptability as good very good, approximately 70% found helpful. Three themes identified: Positive negative comments features, incorrect assumptions content, personal experiences reflections. Significant improvement (P .01) scores from baseline to completion maintained after completion. acceptable effective MS-related fatigue. Identified will guide further development satisfy users' sense autonomy, competence, relatedness.

Язык: Английский

Процитировано

0

Digital Psychiatry: Opportunities, Challenges, and Future Directions DOI

Lana Sidani,

Sunil Nadar,

Jana Tfaili

и другие.

Journal of Psychiatric Practice, Год журнала: 2024, Номер 30(6), С. 400 - 410

Опубликована: Ноя. 1, 2024

Recently, the field of psychiatry has experienced a transformative shift with integration digital tools into traditional therapeutic approaches. Digital encompasses wide spectrum applications, ranging from phenotyping, smartphone wearable devices, virtual/augmented reality, and artificial intelligence (AI). This convergence innovations potential to revolutionize mental health care, enhancing both accessibility patient outcomes. However, despite significant progress in psychiatry, its implementation presents plethora challenges ethical considerations. Critical problems that require careful investigation are raised by issues such as data privacy, divide, legal frameworks, dependability instruments. Furthermore, there risks several hazards associated psychiatric practice. A better understanding growing is needed promote development effective interventions improve accuracy diagnosis. The overarching goal this review paper provide an overview some current opportunities highlighting benefits inherent challenges. also aims at providing guidelines for future research proper clinical

Язык: Английский

Процитировано

0

Combining AI and Human Support in Mental Health: a Digital Intervention with Comparable Effectiveness to Human-delivered Care (Preprint) DOI Creative Commons
Clare E. Palmer, E.A. Marshall, Edward Millgate

и другие.

Journal of Medical Internet Research, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 28, 2024

Escalating mental health demand exceeds existing clinical capacity, requiring scalable digital solutions. However, engagement remains challenging. Conversational agents enhance by making programs more interactive and personalized but have not been widely used. This study evaluated a program for anxiety against external comparators. The used an AI-driven conversational agent to deliver clinician-written content via machine learning, with clinician oversight user support. aimed evaluate the engagement, effectiveness, safety of this structured, evidence-based human support mild, moderate severe generalized anxiety. Statistical analyses determine whether reduced than propensity-matched waiting control was statistically non-inferior real-world face-to-face typed cognitive behavioral therapy (CBT). Prospective participants (N=299) were recruited from NHS or social media in UK given use up 9 weeks (study conducted October 2023 May 2024). Endpoints collected before, during after program, at one-month follow-up. External comparator groups generated through propensity-matching sample Talking Therapies (NHS TT) data ieso Digital Health (typed-CBT) Dorset Healthcare University Foundation Trust (DHC) (face-to-face CBT). Superiority non-inferiority compare symptom reduction (change on GAD-7 scale) group groups. included time spent per participant calculated. Participants median 6 hours over 53 days, 78% (n=232) engaged (i.e. completed 2 14 days). There large clinically meaningful symptoms (per-protocol (PP; n=169): change = -7.4, d 1.6; intention-to-treat (ITT; n=299): -5.4, d=1.1). PP effect superior (d 1.3), CBT (p <.001) typed-CBT <.001). Similarly, ITT sample, showed superiority (d=0.8) (p=.002) approaching significance (p=.06). Effects sustained Clinicians overseeing mean 1.6 (31 - 200 minutes) sessions participant. By combining AI support, achieved outcomes comparable human-delivered care while significantly reducing required 8 times relative global estimates. These findings highlight potential technology scale healthcare, address unmet need, ultimately impact quality life economic burden globally. ISRCTN id: 52546704.

Язык: Английский

Процитировано

0

Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care (Preprint) DOI
Clare E. Palmer,

Eliot Marshall,

Edward Millgate

и другие.

Опубликована: Ноя. 28, 2024

BACKGROUND Escalating mental health demand exceeds existing clinical capacity, necessitating scalable digital solutions. However, engagement remains challenging. Conversational agents can enhance by making programs more interactive and personalized, but they have not been widely adopted. This study evaluated a program for anxiety in comparison to external comparators. The used an artificial intelligence (AI)–driven conversational agent deliver clinician-written content via machine learning, with clinician oversight user support. OBJECTIVE aims evaluate the engagement, effectiveness, safety of this structured, evidence-based human support mild, moderate, severe generalized anxiety. Statistical analyses sought determine whether reduced than propensity-matched waiting control was statistically noninferior real-world, face-to-face typed cognitive behavioral therapy (CBT). METHODS Prospective participants (N=299) were recruited from National Health Service (NHS) or social media United Kingdom given access up 9 weeks (study conducted October 2023 May 2024). End points collected before, during, after program, as well at 1-month follow-up. External comparator groups created through propensity matching sample NHS Talking Therapies (NHS TT) data ieso Digital (typed CBT) Dorset HealthCare (DHC) University Foundation Trust (face-to-face CBT). Superiority noninferiority compare symptom reduction (change on 7-item Generalized Anxiety Disorder Scale [GAD-7]) between group groups. included support, time spent per participant calculated. RESULTS Participants median 6 hours over 53 days, 232 299 (77.6%) engaged (ie, completing 2 14 days). There large, clinically meaningful symptoms (per-protocol [PP; n=169]: mean GAD-7 change –7.4, d=1.6; intention-to-treat [ITT; n= 99]: –5.4, d=1.1). PP effect superior (d=1.3) CBT (<i>P</i>&lt;.001) (<i>P</i>&lt;.001). Similarly, ITT sample, showed superiority (d=0.8) (<i>P</i>=.002), approaching significance (<i>P</i>=.06). Effects sustained Clinicians overseeing 1.6 (range 31-200 minutes) sessions participant. CONCLUSIONS By combining AI achieved outcomes comparable human-delivered care, while significantly reducing required 8 times compared global care estimates. These findings highlight potential technology scale address unmet needs, ultimately impact quality life reduce economic burden globally. CLINICALTRIAL ISRCTN Registry ISRCTN52546704; http://www.isrctn.com/ISRCTN52546704

Язык: Английский

Процитировано

0