Journal of Medical Internet Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 28, 2024
Escalating
mental
health
demand
exceeds
existing
clinical
capacity,
requiring
scalable
digital
solutions.
However,
engagement
remains
challenging.
Conversational
agents
enhance
by
making
programs
more
interactive
and
personalized
but
have
not
been
widely
used.
This
study
evaluated
a
program
for
anxiety
against
external
comparators.
The
used
an
AI-driven
conversational
agent
to
deliver
clinician-written
content
via
machine
learning,
with
clinician
oversight
user
support.
aimed
evaluate
the
engagement,
effectiveness,
safety
of
this
structured,
evidence-based
human
support
mild,
moderate
severe
generalized
anxiety.
Statistical
analyses
determine
whether
reduced
than
propensity-matched
waiting
control
was
statistically
non-inferior
real-world
face-to-face
typed
cognitive
behavioral
therapy
(CBT).
Prospective
participants
(N=299)
were
recruited
from
NHS
or
social
media
in
UK
given
use
up
9
weeks
(study
conducted
October
2023
May
2024).
Endpoints
collected
before,
during
after
program,
at
one-month
follow-up.
External
comparator
groups
generated
through
propensity-matching
sample
Talking
Therapies
(NHS
TT)
data
ieso
Digital
Health
(typed-CBT)
Dorset
Healthcare
University
Foundation
Trust
(DHC)
(face-to-face
CBT).
Superiority
non-inferiority
compare
symptom
reduction
(change
on
GAD-7
scale)
group
groups.
included
time
spent
per
participant
calculated.
Participants
median
6
hours
over
53
days,
78%
(n=232)
engaged
(i.e.
completed
2
14
days).
There
large
clinically
meaningful
symptoms
(per-protocol
(PP;
n=169):
change
=
-7.4,
d
1.6;
intention-to-treat
(ITT;
n=299):
-5.4,
d=1.1).
PP
effect
superior
(d
1.3),
CBT
(p
<.001)
typed-CBT
<.001).
Similarly,
ITT
sample,
showed
superiority
(d=0.8)
(p=.002)
approaching
significance
(p=.06).
Effects
sustained
Clinicians
overseeing
mean
1.6
(31
-
200
minutes)
sessions
participant.
By
combining
AI
support,
achieved
outcomes
comparable
human-delivered
care
while
significantly
reducing
required
8
times
relative
global
estimates.
These
findings
highlight
potential
technology
scale
healthcare,
address
unmet
need,
ultimately
impact
quality
life
economic
burden
globally.
ISRCTN
id:
52546704.
JMIR Mental Health,
Journal Year:
2024,
Volume and Issue:
12, P. e51022 - e51022
Published: Oct. 3, 2024
Fully
automated
digital
interventions
delivered
via
smartphone
apps
have
proven
efficacious
for
a
wide
variety
of
mental
health
outcomes.
An
important
aspect
is
that
they
are
accessible
at
low
cost,
thereby
increasing
their
potential
public
impact
and
reducing
disparities.
However,
major
challenge
to
successful
implementation
the
phenomenon
users
dropping
out
early.
The
purpose
this
study
was
pinpoint
factors
influencing
early
dropout
in
sample
self-selected
virtual
agent
(VA)-based
behavioral
intervention
managing
insomnia,
named
KANOPEE,
which
freely
available
France.
From
January
2021
December
2022,
9657
individuals,
aged
18
years
or
older,
who
downloaded
completed
KANOPEE
screening
interview
had
either
subclinical
clinical
insomnia
symptoms,
4295
(44.5%)
dropped
(ie,
did
not
return
app
continue
filling
subsequent
assessments).
primary
outcome
binary
variable:
having
after
completing
assessment
(early
dropout)
all
treatment
phases
(n=551).
Multivariable
logistic
regression
analysis
used
identify
predictors
among
set
sociodemographic,
clinical,
sleep
diary
variables,
users'
perceptions
program,
collected
during
interview.
mean
age
47.95
(SD
15.21)
years.
Of
those
treatment,
65.1%
(3153/4846)
were
women
34.9%
(1693/4846)
men.
Younger
(adjusted
odds
ratio
[AOR]
0.98,
95%
CI
0.97-0.99),
lower
education
level
(compared
middle
school;
high
school:
AOR
0.56,
0.35-0.90;
bachelor's
degree:
0.35,
0.23-0.52;
master's
degree
higher:
0.22-0.55),
poorer
nocturnal
(sleep
efficiency:
0.64,
0.42-0.96;
number
awakenings:
1.13,
1.04-1.23),
more
severe
depression
symptoms
(AOR
1.12,
1.04-1.21)
significant
out.
When
measures
included
model,
perceived
benevolence
credibility
VA
decreased
0.91,
0.85-0.97).
As
traditional
face-to-face
cognitive
therapy
presence
plays
an
role
dropout.
This
variable
represents
target
address
increase
engagement
with
fully
management
programs.
Furthermore,
our
results
support
contention
can
provide
relevant
user
stimulation
will
eventually
pay
terms
engagement.
BACKGROUND
Artificial
intelligence
(AI)–based
chatbots
have
emerged
as
potential
tools
to
assist
individuals
in
reducing
anxiety
and
supporting
well-being.
OBJECTIVE
This
study
aimed
identify
the
factors
that
impact
individuals’
intention
engage
their
engagement
behavior
with
AI-based
well-being
by
using
a
novel
research
model
enhance
service
levels,
thereby
improving
user
experience
mental
health
intervention
effectiveness.
METHODS
We
conducted
web-based
questionnaire
survey
of
adult
users
China
via
social
media.
Our
collected
demographic
data,
well
range
measures
assess
relevant
theoretical
factors.
Finally,
256
valid
responses
were
obtained.
The
newly
applied
was
validated
through
partial
least
squares
structural
equation
modeling
approach.
RESULTS
explained
62.8%
(<i>R</i><sup>2</sup>)
variance
74%
behavior.
Affect
(β=.201;
<i>P=</i>.002),
(β=.184;
<i>P=</i>.007),
compatibility
(β=.149;
<i>P=</i>.03)
statistically
significant
for
engage.
Habit
(β=.154;
<i>P=</i>.01),
trust
(β=.253;
<i>P<</i>.001),
(β=.464;
<i>P<</i>.001)
CONCLUSIONS
new
extended
provides
basis
studying
users’
chatbot
highlights
practical
points
developers
chatbots.
It
also
importance
create
an
emotional
connection
users.
International Journal of MS Care,
Journal Year:
2024,
Volume and Issue:
26(Q4), P. 347 - 354
Published: Dec. 9, 2024
Fatigue
is
common
in
multiple
sclerosis
(MS);
it
significantly
impairs
quality
of
life,
and
treatment
options
are
limited.
A
randomized
controlled
trial
Elevida,
a
self-guided,
online
German
fatigue
intervention,
showed
significant
benefit.
We
tested
an
English
version
Elevida
with
people
MS
Australia.
Participants
were
volunteers
who
self-reported
at
least
mild
(≥
43
on
the
Scale
for
Motor
Cognitive
Functions
scale),
some
mobility
(Expanded
Disability
Status
<
8),
no
or
cognitive
difficulties
(≤
32
Multiple
Sclerosis
Neuropsychological
Questionnaire).
completed
9-week
program,
commenting
rating
its
acceptability.
The
Chalder
was
baseline,
end-of-program,
2
months
later.
undertook
qualitative
(thematic
analysis)
quantitative
(before/after
differences,
using
paired
t
test)
analyses.
Thirty-eight
expressed
interest
study;
26
eligible;
20
began
study.
Fifteen
participants
(75%)
program
(mean
[SD]:
58.9
[10.5]
years
age,
67%
women,
9
relapsing
MS,
6
progressive
MS).
Over
90%
completing
rated
acceptability
as
good
very
good,
approximately
70%
found
helpful.
Three
themes
identified:
Positive
negative
comments
features,
incorrect
assumptions
content,
personal
experiences
reflections.
Significant
improvement
(P
.01)
scores
from
baseline
to
completion
maintained
after
completion.
acceptable
effective
MS-related
fatigue.
Identified
will
guide
further
development
satisfy
users'
sense
autonomy,
competence,
relatedness.
Journal of Psychiatric Practice,
Journal Year:
2024,
Volume and Issue:
30(6), P. 400 - 410
Published: Nov. 1, 2024
Recently,
the
field
of
psychiatry
has
experienced
a
transformative
shift
with
integration
digital
tools
into
traditional
therapeutic
approaches.
Digital
encompasses
wide
spectrum
applications,
ranging
from
phenotyping,
smartphone
wearable
devices,
virtual/augmented
reality,
and
artificial
intelligence
(AI).
This
convergence
innovations
potential
to
revolutionize
mental
health
care,
enhancing
both
accessibility
patient
outcomes.
However,
despite
significant
progress
in
psychiatry,
its
implementation
presents
plethora
challenges
ethical
considerations.
Critical
problems
that
require
careful
investigation
are
raised
by
issues
such
as
data
privacy,
divide,
legal
frameworks,
dependability
instruments.
Furthermore,
there
risks
several
hazards
associated
psychiatric
practice.
A
better
understanding
growing
is
needed
promote
development
effective
interventions
improve
accuracy
diagnosis.
The
overarching
goal
this
review
paper
provide
an
overview
some
current
opportunities
highlighting
benefits
inherent
challenges.
also
aims
at
providing
guidelines
for
future
research
proper
clinical
Journal of Medical Internet Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 28, 2024
Escalating
mental
health
demand
exceeds
existing
clinical
capacity,
requiring
scalable
digital
solutions.
However,
engagement
remains
challenging.
Conversational
agents
enhance
by
making
programs
more
interactive
and
personalized
but
have
not
been
widely
used.
This
study
evaluated
a
program
for
anxiety
against
external
comparators.
The
used
an
AI-driven
conversational
agent
to
deliver
clinician-written
content
via
machine
learning,
with
clinician
oversight
user
support.
aimed
evaluate
the
engagement,
effectiveness,
safety
of
this
structured,
evidence-based
human
support
mild,
moderate
severe
generalized
anxiety.
Statistical
analyses
determine
whether
reduced
than
propensity-matched
waiting
control
was
statistically
non-inferior
real-world
face-to-face
typed
cognitive
behavioral
therapy
(CBT).
Prospective
participants
(N=299)
were
recruited
from
NHS
or
social
media
in
UK
given
use
up
9
weeks
(study
conducted
October
2023
May
2024).
Endpoints
collected
before,
during
after
program,
at
one-month
follow-up.
External
comparator
groups
generated
through
propensity-matching
sample
Talking
Therapies
(NHS
TT)
data
ieso
Digital
Health
(typed-CBT)
Dorset
Healthcare
University
Foundation
Trust
(DHC)
(face-to-face
CBT).
Superiority
non-inferiority
compare
symptom
reduction
(change
on
GAD-7
scale)
group
groups.
included
time
spent
per
participant
calculated.
Participants
median
6
hours
over
53
days,
78%
(n=232)
engaged
(i.e.
completed
2
14
days).
There
large
clinically
meaningful
symptoms
(per-protocol
(PP;
n=169):
change
=
-7.4,
d
1.6;
intention-to-treat
(ITT;
n=299):
-5.4,
d=1.1).
PP
effect
superior
(d
1.3),
CBT
(p
<.001)
typed-CBT
<.001).
Similarly,
ITT
sample,
showed
superiority
(d=0.8)
(p=.002)
approaching
significance
(p=.06).
Effects
sustained
Clinicians
overseeing
mean
1.6
(31
-
200
minutes)
sessions
participant.
By
combining
AI
support,
achieved
outcomes
comparable
human-delivered
care
while
significantly
reducing
required
8
times
relative
global
estimates.
These
findings
highlight
potential
technology
scale
healthcare,
address
unmet
need,
ultimately
impact
quality
life
economic
burden
globally.
ISRCTN
id:
52546704.