No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory

Neuron, Год журнала: 2021, Номер 109(14), С. 2239 - 2255

Опубликована: Май 19, 2021

Язык: Английский

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Mechanisms of memory under stress

Neuron, Год журнала: 2022, Номер 110(9), С. 1450 - 1467

Опубликована: Март 21, 2022

Язык: Английский

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The Neuropsychology of Anxiety

Oxford University Press eBooks, Год журнала: 2024, Номер unknown

Опубликована: Май 7, 2024

Abstract The Neuropsychology of Anxiety first appeared in 1982 as the volume Oxford Psychology Series, and it quickly established itself classic work on subject. It second edition (appearing 2000) have been cited at a steadily increasing rate passing 500/year 2017. field has continued to expand last quarter century necessitating this third edition. This completely updated revised (with many figures converted colour) retains original core concepts while expanding often simplifying details. includes new chapter prefrontal cortex, which integrates frontal hippocampal views anxiety an extensively modified personality providing basis for further developments Reinforcement Sensitivity Theory. book is essential postgraduate students researchers experimental psychology neuroscience, well all clinical psychologists psychiatrists.

Язык: Английский

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The homogenous hippocampus: How hippocampal cells process available and potential goals

Progress in Neurobiology, Год журнала: 2024, Номер 240, С. 102653 - 102653

Опубликована: Июль 2, 2024

We present here a view of the firing patterns hippocampal cells that is contrary, both functionally and anatomically, to conventional wisdom. argue hippocampus responds efference copies goals encoded elsewhere; it uses these detect resolve conflict or interference between in general. While can involve space, do not encode spatial (or other special types of) memory, as such. also transverse circuits operate an essentially homogeneous way along its length. The apparently different functions parts (e.g. memory retrieval versus anxiety) result from (situational/motivational) inputs on which those perform same fundamental computational operations. On this view, key role iterative adjustment, via Papez-like circuits, synaptic weights cell assemblies elsewhere.

Язык: Английский

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Systems consolidation, transformation and reorganization: Multiple Trace Theory, Trace Transformation Theory and their Competitors

Опубликована: Май 10, 2021

We review the literature on systems consolidation by providing a brief history of field to place current research in proper perspective. cover both humans and non-humans, which are highly related despite differences techniques tasks that used. argue understanding interactions between hippocampus neocortex (and other structures) underlie consolidation, depend appreciating close correspondence psychological neural representations memory, as postulated Multiple Trace Theory Transformation Theory. end evaluating different theories light evidence we reviewed suggest concept with its central concern time-limited role plays may have outlived usefulness. replacing it program processes mechanisms changes memory across lifetime – natural change.

Язык: Английский

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A model of autonomous interactions between hippocampus and neocortex driving sleep-dependent memory consolidation

Proceedings of the National Academy of Sciences, Год журнала: 2022, Номер 119(44)

Опубликована: Окт. 24, 2022

How do we build up our knowledge of the world over time? Many theories memory formation and consolidation have posited that hippocampus stores new information, then “teaches” this information to neocortex time, especially during sleep. But it is unclear, mechanistically, how actually works—How are these systems able interact periods with virtually no environmental input accomplish useful learning shifts in representation? We provide a framework for thinking about question, neural network model simulations serving as demonstrations. The composed neocortical areas, which replay memories one another completely autonomously simulated Oscillations leveraged support error-driven leads changes representation behavior. has non–rapid eye movement (NREM) sleep stage, where dynamics between tightly coupled, helping reinstate high-fidelity versions attractors, REM more freely explore existing attractors. find alternating NREM stages, alternately focuses model’s on recent remote facilitates graceful continual learning. thus an account can without any external drive cortical protect old integrated.

Язык: Английский

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Short- and long-delay consolidation of memory accessibility and precision across childhood and young adulthood.

Developmental Psychology, Год журнала: 2024, Номер 60(5), С. 891 - 903

Опубликована: Март 21, 2024

Childhood is a period when memory consolidation and knowledge base undergo rapid changes. The present study examined short-delay (overnight) long-delay (after 2-week period) of new information either congruent or incongruent with prior in typically developing 6- to 8-year-old children (

Язык: Английский

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Organizing memories for generalization in complementary learning systems

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2021, Номер unknown

Опубликована: Окт. 15, 2021

ABSTRACT Memorization and generalization are complementary cognitive processes that jointly promote adaptive behavior. For example, animals should memorize a safe route to water source generalize features allow them find new sources, without expecting paths exactly resemble previous ones. Memory aids by allowing the brain extract general patterns from specific instances were spread across time, such as when humans progressively build semantic knowledge episodic memories. This process depends on neural mechanisms of systems consolidation, whereby hippocampal-neocortical interactions gradually construct neocortical memory traces consolidating hippocampal precursors. However, recent data suggest consolidation only applies subset memories; why certain memories consolidate more than others remains unclear. Here we introduce novel network formalization highlights an overlooked tension between transfer generalization, resolve this postulating it generalization. We specifically show unregulated can be detrimental in unpredictable environments, whereas optimizing for generates high-fidelity, dual-system supporting both theory generalization-optimized produces transfers some components neocortex leaves dependent hippocampus. It thus provides normative principle reconceptualizing numerous puzzling observations field insight into how behavior benefits learning specialized memorization

Язык: Английский

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Accuracy and reconstruction in autobiographical memory: (Re)consolidating neuroscience and sociocultural developmental approaches

Wiley Interdisciplinary Reviews Cognitive Science, Год журнала: 2022, Номер 14(3)

Опубликована: Сен. 20, 2022

Abstract Autobiographical memories are never isolated episodes; they embedded in a network that is continually updated and prediction driven. We present autobiographical memory as meaning‐driven process includes both veridical traces reconstructive schemas. Our developmental approach delineates how develops across childhood throughout adulthood, our sociocultural examines the ways which shaped by everyday social interactions within cultural worldviews. These approaches enhanced focus on functions, namely self‐coherence, embeddedness, directing future behaviors. Neuroscience models of outlined multiple trace transformation theories perceptual principles predictive processing establish mechanisms frameworks into processes incorporated. Rather than conceptualizing episodic accurate versus error‐prone, we frame dynamic continuously to create coherent meaning for individuals living complex worlds. accuracy error, an intricate weaving specific details, inferences confusions among similar experiences; it incorporates post‐event information through reminiscing conversations, service creating more meaningful define self, others, world. This article categorized under: Psychology > Memory

Язык: Английский

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Intersubject similarity in neural representations underlies shared episodic memory content

Proceedings of the National Academy of Sciences, Год журнала: 2023, Номер 120(35)

Опубликована: Авг. 21, 2023

Individuals generally form their unique memories from shared experiences, yet the neural representational mechanisms underlying this subjectiveness of memory are poorly understood. The current study addressed important question cross-subject perspective, leveraging a large functional magnetic resonance imaging dataset ( n = 415) face–name associative task. We found that individuals’ abilities were predicted by synchronization to group-averaged, canonical trial-by-trial activation level and, lesser degree, similarity group-averaged patterns during encoding. More importantly, content between pairs participants could be local pattern, particularly in angular gyrus and ventromedial prefrontal cortex, even after controlling for differences abilities. These results uncover individualized underscore constructive nature episodic memory.

Язык: Английский

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