No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory

Neuron, Journal Year: 2021, Volume and Issue: 109(14), P. 2239 - 2255

Published: May 19, 2021

Language: Английский

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Mechanisms of memory under stress

Neuron, Journal Year: 2022, Volume and Issue: 110(9), P. 1450 - 1467

Published: March 21, 2022

Language: Английский

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The Neuropsychology of Anxiety

Oxford University Press eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: May 7, 2024

Abstract The Neuropsychology of Anxiety first appeared in 1982 as the volume Oxford Psychology Series, and it quickly established itself classic work on subject. It second edition (appearing 2000) have been cited at a steadily increasing rate passing 500/year 2017. field has continued to expand last quarter century necessitating this third edition. This completely updated revised (with many figures converted colour) retains original core concepts while expanding often simplifying details. includes new chapter prefrontal cortex, which integrates frontal hippocampal views anxiety an extensively modified personality providing basis for further developments Reinforcement Sensitivity Theory. book is essential postgraduate students researchers experimental psychology neuroscience, well all clinical psychologists psychiatrists.

Language: Английский

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The homogenous hippocampus: How hippocampal cells process available and potential goals

Progress in Neurobiology, Journal Year: 2024, Volume and Issue: 240, P. 102653 - 102653

Published: July 2, 2024

We present here a view of the firing patterns hippocampal cells that is contrary, both functionally and anatomically, to conventional wisdom. argue hippocampus responds efference copies goals encoded elsewhere; it uses these detect resolve conflict or interference between in general. While can involve space, do not encode spatial (or other special types of) memory, as such. also transverse circuits operate an essentially homogeneous way along its length. The apparently different functions parts (e.g. memory retrieval versus anxiety) result from (situational/motivational) inputs on which those perform same fundamental computational operations. On this view, key role iterative adjustment, via Papez-like circuits, synaptic weights cell assemblies elsewhere.

Language: Английский

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Systems consolidation, transformation and reorganization: Multiple Trace Theory, Trace Transformation Theory and their Competitors

Published: May 10, 2021

We review the literature on systems consolidation by providing a brief history of field to place current research in proper perspective. cover both humans and non-humans, which are highly related despite differences techniques tasks that used. argue understanding interactions between hippocampus neocortex (and other structures) underlie consolidation, depend appreciating close correspondence psychological neural representations memory, as postulated Multiple Trace Theory Transformation Theory. end evaluating different theories light evidence we reviewed suggest concept with its central concern time-limited role plays may have outlived usefulness. replacing it program processes mechanisms changes memory across lifetime – natural change.

Language: Английский

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A model of autonomous interactions between hippocampus and neocortex driving sleep-dependent memory consolidation

Proceedings of the National Academy of Sciences, Journal Year: 2022, Volume and Issue: 119(44)

Published: Oct. 24, 2022

How do we build up our knowledge of the world over time? Many theories memory formation and consolidation have posited that hippocampus stores new information, then “teaches” this information to neocortex time, especially during sleep. But it is unclear, mechanistically, how actually works—How are these systems able interact periods with virtually no environmental input accomplish useful learning shifts in representation? We provide a framework for thinking about question, neural network model simulations serving as demonstrations. The composed neocortical areas, which replay memories one another completely autonomously simulated Oscillations leveraged support error-driven leads changes representation behavior. has non–rapid eye movement (NREM) sleep stage, where dynamics between tightly coupled, helping reinstate high-fidelity versions attractors, REM more freely explore existing attractors. find alternating NREM stages, alternately focuses model’s on recent remote facilitates graceful continual learning. thus an account can without any external drive cortical protect old integrated.

Language: Английский

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Short- and long-delay consolidation of memory accessibility and precision across childhood and young adulthood.

Developmental Psychology, Journal Year: 2024, Volume and Issue: 60(5), P. 891 - 903

Published: March 21, 2024

Childhood is a period when memory consolidation and knowledge base undergo rapid changes. The present study examined short-delay (overnight) long-delay (after 2-week period) of new information either congruent or incongruent with prior in typically developing 6- to 8-year-old children (

Language: Английский

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Organizing memories for generalization in complementary learning systems

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2021, Volume and Issue: unknown

Published: Oct. 15, 2021

ABSTRACT Memorization and generalization are complementary cognitive processes that jointly promote adaptive behavior. For example, animals should memorize a safe route to water source generalize features allow them find new sources, without expecting paths exactly resemble previous ones. Memory aids by allowing the brain extract general patterns from specific instances were spread across time, such as when humans progressively build semantic knowledge episodic memories. This process depends on neural mechanisms of systems consolidation, whereby hippocampal-neocortical interactions gradually construct neocortical memory traces consolidating hippocampal precursors. However, recent data suggest consolidation only applies subset memories; why certain memories consolidate more than others remains unclear. Here we introduce novel network formalization highlights an overlooked tension between transfer generalization, resolve this postulating it generalization. We specifically show unregulated can be detrimental in unpredictable environments, whereas optimizing for generates high-fidelity, dual-system supporting both theory generalization-optimized produces transfers some components neocortex leaves dependent hippocampus. It thus provides normative principle reconceptualizing numerous puzzling observations field insight into how behavior benefits learning specialized memorization

Language: Английский

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Autobiographical memory loss in Alzheimer's disease: The role of the reminiscence bump

Cortex, Journal Year: 2022, Volume and Issue: 150, P. 137 - 148

Published: March 9, 2022

Research on autobiographical memory loss in Alzheimer's disease (AD) is characterized by conflicting findings concerning a possible sparing of older memories. The literature shows evidence for both negative temporal gradient, flat gradient and reminiscence bump - that is, disproportionally high frequency memories from early adulthood relative to surrounding periods. Here, we expanded the number lifetime periods Autobiographical Memory Interview (AMI; Kopelman, Wilson & Baddeley, 1989, 1990) standard three seven order increase sensitivity test variations distribution across life span. Twenty-five adults diagnosed with AD (MMMSE = 21.16, SD 5.08) matched sample 30 healthy, were assessed. personal semantic information showed steadily decreasing middle childhood present life, consistent predictions derived consolidation theories. In comparison, incidents/episodic produced patients response AMI predominance age 6 30, followed steep drop referring events had occurred after 30. This challenges theories retrograde amnesia showing neither progressively later nor gradient. contrast, identified research. Schematization retrieval support provided cultural scripts are discussed.

Language: Английский

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Forgetting rates of gist and peripheral episodic details in prose recall

Memory & Cognition, Journal Year: 2022, Volume and Issue: 51(1), P. 71 - 86

Published: April 13, 2022

Abstract In a seminal study, Slamecka and McElree showed that the degree of initial learning verbal material affected intercepts but not slopes forgetting curves. However, more recent work has reported memories for central events (gist) memory secondary details (peripheral) were forgotten at different rates over periods days, with gist retained consistently time than details. The present experiments aimed to investigate whether qualitatively types scoring (gist vs. peripheral) are in prose recall. three experiments, 232 participants listened two narratives subsequently asked freely recall stories. first tested repeatedly after days month, while third experiment they only month control repeated retrieval. Memory was higher peripheral details, which faster rate or without presence intermediate Moreover, retrieval had significant benefit on both We conclude nature leads differential free recall, does have effect retention these episodic

Language: Английский

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