Critical Reviews in Food Science and Nutrition,
Год журнала:
2025,
Номер
unknown, С. 1 - 15
Опубликована: Апрель 26, 2025
Omega-3
fatty
acids
(n-3
FAs),
including
alpha-linolenic
acid,
eicosapentaenoic
acid
(EPA),
and
docosahexaenoic
(DHA),
are
essential
for
human
health,
significantly
contributing
to
cardiovascular
neurocognitive
function,
immune
modulation.
Traditionally,
these
sourced
from
flaxseeds,
walnuts,
fish
like
salmon
mackerel.
Recently,
microalgae
have
gained
attention
as
a
sustainable
source
of
n-3
FAs,
they
primary
producers
EPA
DHA
in
aquatic
ecosystems.
This
review
examines
production
extraction
methods,
evaluating
their
efficiency
oxidative
stability.
It
explores
both
chemical
natural
synthesis
FAs
reviews
advanced
analytical
techniques
accurate
identification
quantification.
The
addresses
current
research
on
improved
microalgae,
highlighting
the
limitations
microreactors
laboratory-scale
optimizations.
also
growth
parameters
necessary
successful
scale-up
cultivation,
focusing
light
intensity,
mixing,
mass
transfer,
temperature,
pH.
However,
is
primarily
limited
studies,
necessitating
further
exploration
into
large-scale
applications.
Optimizing
such
agitation,
pH,
temperature
enhanced
transfer
crucial
scale-up.
case
study
raceway
open
pond
systems
illustrates
potential
commercial-scale
emphasizing
need
continued
achieve
sustainable,
microalgae-derived
FAs.
Frontiers in Microbiology,
Год журнала:
2023,
Номер
14
Опубликована: Ноя. 7, 2023
Omega-3
fatty
acids,
including
alpha-linolenic
acids
(ALA),
eicosapentaenoic
acid
(EPA),
and
docosahexaenoic
(DHA),
have
shown
major
health
benefits,
but
the
human
body’s
inability
to
synthesize
them
has
led
necessity
of
dietary
intake
products.
The
omega-3
market
grown
significantly,
with
a
global
from
an
estimated
USD
2.10
billion
in
2020
predicted
nearly
3.61
2028.
However,
obtaining
sufficient
supply
high-quality
stable
can
be
challenging.
Currently,
fish
oil
serves
as
primary
source
market,
it
several
drawbacks,
high
cost,
inconsistent
product
quality,
uncertainties
its
sustainability
ecological
impact.
Other
significant
sources
include
plants
microalgae
fermentation,
they
face
similar
challenges
reducing
manufacturing
costs
improving
quality
sustainability.
With
advances
synthetic
biology,
biotechnological
production
via
engineered
microbial
cell
factories
still
offers
best
solution
provide
more
stable,
sustainable,
affordable
by
overcoming
issues
associated
conventional
sources.
This
review
summarizes
current
status,
key
challenges,
future
perspectives
for
acids.
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Апрель 12, 2024
A
large
number
of
microbial
species
tend
to
communicate
and
produce
biofilm
which
causes
numerous
infections,
antibiotic
resistance,
economic
problems
across
different
industries.
Therefore,
advanced
anti-biofilms
are
required
with
novel
attributes
targets,
such
as
quorum
sensing
communication
system.
Meanwhile,
inhibitors
promising
anti-biofilm
molecules
result
in
the
inhibition
particular
phenotype
expression
blocking
cell-to-cell
communication,
would
be
more
acceptable
than
conventional
strategies.
Many
natural
products
identified
agents
from
plants,
microorganisms,
marine
extracts.
Marine
algae
sources
broadly
compounds
activity.
Algae
extracts
their
metabolites
sulfated
polysaccharides
(fucoidan),
carotenoids
(zeaxanthin
lutein),
lipid
fatty
acids
(γ-linolenic
acid
linoleic
acid),
phlorotannins
can
inhibit
cell
attachment,
reduce
growth,
interfere
pathway
by
related
enzymes,
disrupt
extracellular
polymeric
substances.
In
this
review,
mechanisms
formation,
pathway,
recently
will
discussed.
Biotechnology Journal,
Год журнала:
2024,
Номер
19(3)
Опубликована: Март 1, 2024
Abstract
Microalgae
are
considered
to
be
a
promising
group
of
organisms
for
fuel
production,
waste
processing,
pharmaceutical
applications,
and
as
source
food
components.
Unicellular
algae
worth
being
because
their
capacity
produce
comparatively
large
amounts
lipids,
proteins,
vitamins
while
requiring
little
room
growth.
They
can
also
grow
on
fix
CO2
nitrogen
compounds.
However,
production
costs
limit
the
industrial
use
microalgae
most
profitable
applications
including
micronutrient
fish
farming.
Therefore,
novel
based
technologies
require
an
increase
efficiencies
or
values.
Here
we
review
recent
studies
focused
getting
strains
with
characteristics
cultivating
techniques
that
improve
production's
robustness
efficiency
categorize
these
findings
according
fundamental
factors
determine
Improvements
light
nutrient
delivery,
well
other
aspects
photobioreactor
design,
have
shown
highest
average
in
productivity.
Other
methods,
such
improvement
phosphorus
fixation
temperature
adaptation
been
found
less
effective.
Furthermore,
interactions
particular
bacteria
may
promote
growth
microalgae,
although
bacterial
grazer
contaminations
must
managed
avoid
culture
failure.
The
competitiveness
algal
products
will
if
discoveries
applied
settings.
Antioxidants,
Год журнала:
2023,
Номер
12(10), С. 1882 - 1882
Опубликована: Окт. 19, 2023
Microalgae
are
a
renewable
and
sustainable
source
of
bioactive
compounds,
such
as
essential
amino
acids,
polyunsaturated
fatty
antioxidant
that
have
been
documented
to
beneficial
effects
on
nutrition
health.
Among
these
natural
products,
the
demand
for
antioxidants,
an
alternative
synthetic
has
increased.
The
activity
microalgae
significantly
varies
between
species
depends
growth
conditions.
In
last
decade,
explored
in
livestock
animals
feed
additives
with
aim
improving
both
animals’
health
performance
well
product
quality
environmental
impact
livestock.
These
findings
highly
dependent
composition
strain
their
amount
diet.
use
carbohydrate-active
enzymes
can
increase
nutrient
bioavailability
consequence
recalcitrant
cell
wall
degradation,
making
it
promising
strategy
monogastric
productivity.
conventional
feedstuffs
is
becoming
increasingly
important
due
food–feed
competition,
land
water
deprivation,
climate
change.
However,
cost-effective
production
major
challenge
near
future,
cultivation
technology
should
be
improved
by
reducing
costs,
thus
increasing
profitability.
Chinese Journal of Chemistry,
Год журнала:
2023,
Номер
42(6), С. 652 - 685
Опубликована: Ноя. 7, 2023
Comprehensive
Summary
Polyhydroxyurethanes
(PHUs)
have
received
considerable
attention
in
the
last
decade
as
potential
alternatives
to
traditional
phosgene‐based
polyurethanes
(PUs).
The
development
of
suitable
5CC
(five
membered‐ring
cyclic
carbonate)
precursors
bearing
multiple
carbonate
moieties
(multi‐5CCs)
is
a
key
requisite
for
preparing
PHUs
by
polyaddition
reaction
with
bis‐
or
polyamines.
Producing
sustainable
from
CO
2
‐based
five‐membered
carbonates
(5CCs)
obtained
biobased
epoxides
valuable
strategy
bridge
utilization
and
upcycling
renewable
substrates.
In
this
context,
while
many
multi‐5CC
monomers
reported
literature
are
oil‐based,
recent
efforts
led
large
variety
multifunctional
5CCs
that
produced
combination
resources
such
fatty
acids
vegetable
oils,
lignin,
terpenes,
sugars.
work,
crucial
advances
(2019—2023)
on
prepared
multi‐5CCs
(partially/potentially)
substrates
reviewed
respect
their
synthesis,
thermal
mechanical
properties,
recent,
emerging
applications.