Aptasensors and Advancement in Molecular Recognition Technology

Advanced Materials Technologies, Год журнала: 2024, Номер unknown

Опубликована: Июль 2, 2024

Abstract Synthetic oligonucleic acids known as aptamers exhibit remarkable selectivity and affinity for target recognition binding. Selected via an iterative process “selective evolution of ligands by exponential enrichment” (SELEX), fold into defined 3D conformations to interact with their targets. The incorporation elements has driven notable progress in biosensors, giving rise the development aptasensors. Here, aptamer discovery various types aptasensors are summarized. fundamental design principles elaborated along superiority compared antibodies. modes employed aptasensors, such structure‐switching design, hybridization chain reaction amplification, enzyme‐assisted recycling, split examined. Further light is shed on diverse landscape adaptability different analytes well potential propel advancements modern biosensor technology. As a nucleic acids‐based platform, poise become next generation sensitive cost‐effective technology shape future molecular biosensing.

Язык: Английский

A Review of Aptamer-Based Surface-Enhanced Raman Scattering (SERS) Platforms for Cancer Diagnosis Applications

BioNanoScience, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 3, 2024

Язык: Английский