Springer eBooks, Год журнала: 2024, Номер unknown, С. 1 - 51
Опубликована: Янв. 1, 2024
Язык: Английский
Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)
Опубликована: Янв. 18, 2025
Artificial oxygen carriers have emerged as potential substitutes for red blood cells in situations of major loss, including accidents, surgical procedures, trauma, childbirth, stomach ulcers, hemorrhagic shock, and vessel ruptures which can lead to sudden reduction volume. The therapeutic delivery utilizing artificial cell presents a promising avenue treating spectrum disease models. Apart from that, the recent advancement intended supplant conventional transfusions draws significant attention due exigencies warfare ongoing challenges posed by COVID-19 pandemic. However, there is pressing need formulate stable, non-toxic, immunologically inert carriers. Even though numerous are encountered development carriers, their applicability extends various medical treatments, encompassing elective cardiovascular surgeries, decompression illness, acute stroke, myocardial infarction, sickle crisis, proficient addressing conditions such cerebral hypoxia. Therefore, this paper provides an overview using assorted types hemoglobin-based, perfluorocarbon-based, stem cell-derived, micro/nanobubbles, treatment diverse Additionally, it discusses side effects limitations associated with these interventions, while incorporating completed research clinical developments. Finally, prospective solutions general demands perfect were anticipated be reference subsequent endeavors.
Язык: Английский
Процитировано
3
Bioactive Materials, Год журнала: 2024, Номер 40, С. 227 - 243
Опубликована: Июнь 14, 2024
Язык: Английский
Процитировано
10
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(6), С. 3480 - 3480
Опубликована: Март 20, 2024
Promoting the efficiency of bone regeneration in loss diseases is a significant clinical challenge. Traditional therapies often fail to achieve better therapeutic outcomes and shorter treatment times. However, recent years, extracellular vesicles (EVs) have gained attention due their exceptional osteogenic function superior effects compared traditional cell therapy. EVs emerged as promising therapy for tissue defect various physiological functions, such regulating immune response promoting repair regeneration. Moreover, good biocompatibility, low immunogenicity, long-term stability, can be improved through pretreatment other methods. Studies investigating mechanisms by which promote applying from different sources using methods animal models defects increased. Therefore, this paper reviews types used regeneration, sources, roles, delivery pathways, scaffold biomaterials, applications.
Язык: Английский
Процитировано
4
European Journal of Medicinal Chemistry Reports, Год журнала: 2025, Номер unknown, С. 100263 - 100263
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Journal of Clinical & Translational Endocrinology, Год журнала: 2024, Номер 37, С. 100366 - 100366
Опубликована: Авг. 30, 2024
In recent years, the prevalence of diabetic wounds has significantly increased, posing a substantial medical challenge due to their propensity for infection and delayed healing. These not only increase mortality rates but also lead amputations severe mobility issues. To address this, advancements in bioactive molecules such as genes, growth factors, proteins, peptides, stem cells, exosomes into targeted gene therapies have emerged preferred strategy among researchers. Additionally, integration photothermal therapy (PTT), nucleic acid, therapy, along with 3D printing technology layer-by-layer (LBL) self-assembly approach, shows promise wound treatment. Effective delivery small interfering RNA (siRNA) relies on vectors. This review provides an in-depth exploration pathophysiological characteristics observed wounds, encompassing diminished angiogenesis, heightened levels reactive oxygen species, impaired immune function. It further examines acid delivery, advanced drug systems, techniques, negative pressure (NPWT), printing, hyperbaric ongoing clinical trials. Through research insights, this presents innovative strategies aimed at augmenting multifaceted management thus paving way enhanced therapeutic outcomes future.
Язык: Английский
Процитировано
3
Springer eBooks, Год журнала: 2024, Номер unknown, С. 2257 - 2307
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
1
Precision and Future Medicine, Год журнала: 2024, Номер unknown
Опубликована: Дек. 16, 2024
Stem cells in regenerative medicine are advancing rapidly, with significant progress made recent years.Our bibliometric review is a contribution to the field and essential for research.However, there noticeable lack of reviews that focus on stem their clinical applications medicine.Our study addressed this gap using advanced tools such as R-Studio VOSviewer explore publication volumes, intellectual structures, emerging trends field, ensuring validity reliability our findings.We utilized Scopus Web Science extract 1,274 relevant articles employed rigorous descriptive analysis, co-occurrence text-mining techniques.Our identified most influential journals based productivity citation volume.
Язык: Английский
Процитировано
1
Springer eBooks, Год журнала: 2024, Номер unknown, С. 1 - 51
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0