Musculoskeletal Science and Practice, Год журнала: 2024, Номер 75, С. 103238 - 103238
Опубликована: Ноя. 29, 2024
Язык: Английский
Musculoskeletal Science and Practice, Год журнала: 2024, Номер 75, С. 103238 - 103238
Опубликована: Ноя. 29, 2024
Язык: Английский
Healthcare, Год журнала: 2025, Номер 13(3), С. 324 - 324
Опубликована: Фев. 4, 2025
Recent advances in artificial intelligence (AI) and telemedicine are transforming healthcare delivery, particularly rural underserved communities. Background/Objectives: The purpose of this systematic review is to explore the use AI-driven diagnostic tools platforms identify underlying themes (constructs) literature across multiple research studies. Method: team conducted an extensive studies articles using databases that aimed consistent patterns literature. Results: Five constructs were identified with regard utilization AI on patient diagnosis communities: (1) Challenges/benefits communities, (2) Integration monitoring, (3) Future considerations (4) Application for accurate early diseases through various digital tools, (5) Insights into future directions potential innovations specifically geared towards enhancing delivery Conclusions: While technologies offer enhanced capabilities by processing vast datasets medical records, imaging, histories, leading earlier more diagnoses, acts as a bridge between patients remote areas specialized providers, offering timely access consultations, follow-up care, chronic disease management. Therefore, integration allows real-time decision support, improving clinical outcomes providing data-driven insights during virtual consultations. However, challenges remain, including ensuring equitable these technologies, addressing literacy gaps, managing ethical implications decisions. Despite hurdles, hold significant promise reducing disparities advancing quality care settings, potentially improved long-term health populations.
Язык: Английский
Процитировано
4Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13
Опубликована: Фев. 11, 2025
Three-dimensional (3D) printing has rapidly become a transformative force in orthopedic surgery, enabling the creation of highly customized and precise medical implants surgical tools. This review aims to provide more systematic comprehensive perspective on emerging 3D technologies—ranging from extrusion-based methods bioink powder bed fusion—and broadening array materials, including bioactive agents cell-laden inks. We highlight how these technologies materials are employed fabricate patient-specific implants, guides, prosthetics, advanced tissue engineering scaffolds, significantly enhancing outcomes patient recovery. Despite notable progress, field faces challenges such as optimizing mechanical properties, ensuring structural integrity, addressing regulatory complexities across different regions, considering environmental impacts cost barriers, especially low-resource settings. Looking ahead, innovations smart functionally graded (FGMs), along with advancements bioprinting, hold promise for overcoming obstacles expanding capabilities orthopedics. underscores pivotal role interdisciplinary collaboration ongoing research harnessing full potential additive manufacturing, ultimately paving way effective, personalized, durable solutions that improve quality life.
Язык: Английский
Процитировано
2Indus journal of bioscience research., Год журнала: 2025, Номер 3(1), С. 344 - 353
Опубликована: Янв. 16, 2025
Spinal fusion surgery is a critical procedure used to treat various spinal disorders, including degenerative diseases, deformities, trauma, and tumors. Over the past few decades, advancements have been made improve patient outcomes, reduce complications, shorten recovery times. This review highlights key innovations in techniques, focusing on minimally invasive approaches, robotic-assisted surgery, biologic therapies, advanced implants. Minimally techniques offer benefits such as reduced blood loss, less postoperative pain, shorter hospital stays compared traditional open surgeries, though their success depends surgeon’s expertise. Robotic-assisted has transformed implant placement, enhancing precision reducing screw misplacement, leading improved long-term outcomes. However, high cost steep learning curve remain obstacles for widespread adoption. Biologic treatments, bone morphogenetic proteins (BMPs) stem cells, shown promise improving rates accelerating healing, but concerns regarding safety efficacy continue. The development of 3D-printed implants dynamic stabilization systems provides personalized solutions, offering better fit biomechanical compatibility while potentially adjacent segment degeneration. Additionally, incorporating artificial intelligence (AI) machine (ML) surgical planning care holds potential optimize treatment strategies, predict patient-specific While these show great promise, challenges cost, accessibility, need further clinical validation persist. future will depend continued integration technologies, precision, more tailored treatments enhanced outcomes health.
Язык: Английский
Процитировано
0Опубликована: Март 17, 2025
Mineral nanoparticles and osteoinductive biomaterials are essential in advancing bone regeneration by addressing skeletal conditions injuries that compromise structural integrity functionality. These stimulate the differentiation of precursor cells into osteoblasts, creating biocompatible environments conducive to tissue regeneration. Among most promising innovations, mineral-based nanocomposite hydrogels have emerged as effective strategies for enhancing potential. This review explores diverse types biomaterials, including natural sources, synthetic compounds, hybrid designs incorporate mineralized nanoparticles. Emphasis is placed on polymeric delivery platforms these materials, highlighting their dual role supports bioactive agents promote osteogenesis. Challenges such immune rejection, biodegradability, mechanical stability, short vivo residence time critically discussed, alongside impact clinical translation. By presenting a comprehensive analysis mechanisms, applications, limitations, this identifies opportunities integrating with emerging fields like immunology biomechanics. Ultimately, work aims provide actionable insights advance development novel, clinically relevant solutions improve patient outcomes address growing global need repair
Язык: Английский
Процитировано
0Journal of Orthopaedics, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Orthopedic Reviews, Год журнала: 2025, Номер 17
Опубликована: Март 31, 2025
Musculoskeletal injuries and degenerative conditions necessitate advanced regenerative solutions. Tissue engineering has emerged as a pivotal field in orthopedic care, particularly vascularized bone cartilage regeneration. This narrative review examines the latest advancements vascular tissue engineering, including scaffold design, cell-based techniques, growth factor delivery. A comprehensive literature search was conducted using PubMed, ScienceDirect, Google Scholar, focusing on innovations challenges field. Vascularized grafts (VBGs) outperform non-vascularized counterparts promoting healing integration. Advances materials, such smart scaffolds hybrid biomaterials, enhance osteogenesis angiogenesis. Cellular therapies, utilizing mesenchymal stem cells induced pluripotent cells, synergistically improve vascularization Growth factors like VEGF morphogenic protein (BMP-2), integrated with innovative delivery systems, enable sustained angiogenic stimulation While significant strides have been made, persist achieving full integration replicating native architecture. Innovations technology surgery techniques hold promise for transforming improving patient outcomes.
Язык: Английский
Процитировано
0Lasers in Medical Science, Год журнала: 2025, Номер 40(1)
Опубликована: Апрель 8, 2025
Язык: Английский
Процитировано
0BMC Surgery, Год журнала: 2025, Номер 25(1)
Опубликована: Янв. 29, 2025
Intramedullary tibial nailing is a standard treatment for shaft fractures. Postoperative knee pain significantly impacts functional recovery; however, studies on this issue are limited. This study evaluated the effect of parapatellar approach intramedullary postoperative pain. A total 29 patients with fractures treated nails from March 2019 to January 2022 were divided into two groups based surgical approach: semi-extended lateral and conventional subpatellar ligament split approach. Recorded metrics included operation time, intraoperative fluoroscopy count, bleeding volume, Visual Analog Scale (VAS) scores at 24 h, 72 1 week, month postoperatively, fracture healing time Lysholm 12 months. Both completed without significant differences in bleeding, or (P > 0.05). The group showed better VAS week postoperatively compared control < 0.05), no difference month. After months, indicated support, locking, swelling 0.05); improvements lameness, instability, stair climbing, squatting, Overall, outperformed = 0.01). Additionally, long-term follow-up revealed potential advantages improving outcomes. Using avoids splitting patellar entering joint cavity, minimizing impact effectively reducing pain, benefits recovery.
Язык: Английский
Процитировано
0Journal of Arthroscopic Surgery and Sports Medicine, Год журнала: 2024, Номер 4, С. 27 - 29
Опубликована: Март 28, 2024
Язык: Английский
Процитировано
2Gels, Год журнала: 2024, Номер 10(6), С. 396 - 396
Опубликована: Июнь 12, 2024
(1) Background: There is a lack of knowledge about how single dose COX-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) might affect the release growth factors (GFs) and cytokines from canine platelet-rich gels (PRGs) other hemocomponents. (2) Methods: A crossover study was conducted in six adult mongrel dogs. Animals were randomized to receive either carprofen or firocoxib. PRG, temperature-induced platelet lysate (TIPL), chemically induced PL (CIPL), plasma hemocomponents obtained each dog before (1 h) after (6 treatments. Platelet leukocyte counts determination concentrations platelet-derived factor-BB, (PDGF-BB), transforming factor beta-1 (TGF-β1), interleukin 1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α) IL-10 assayed by ELISA all (3) Results: Both PDGF-BB not affected NSAIDs time. Total TGF-β1 NSAIDs; however, this GF increased PRG supernatants (PRGS) at 6 h. IL-1β TNF-α significantly (p < 0.001) lower both firocoxib PRGS h, respectively. h treated with NSAIDs. (4) Conclusions: The clinical implications our findings could indicate that these should be withdrawn patients allow their clearance use PRP/PRG. On hand, prophylactic avoid inflammatory reactions some have PRP/PRG treatment performed only those animals severe reactive inflammation treatment.
Язык: Английский
Процитировано
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