Migrasomes, critical players in intercellular communication
Cancer Cell International,
Год журнала:
2025,
Номер
25(1)
Опубликована: Март 25, 2025
Migrasomes
are
a
newly
discovered
type
of
extracellular
vesicle
(EV)
formed
during
cell
migration,
playing
pivotal
role
in
intercellular
communication.
These
vesicles
generated
by
retracting
fibers
migrating
cells
and
encapsulate
various
molecules,
such
as
proteins,
lipids,
RNA,
allowing
the
transfer
biochemical
signals
to
neighboring
cells.
Current
evidence
suggests
that
migrasomes
involved
wide
range
physiological
processes
embryogenesis,
angiogenesis,
immune
modulation,
mitochondrial
quality
control.
Moreover,
implicated
pathological
conditions,
including
cancer
metastasis,
cardiovascular
diseases,
viral
infections.
To
fully
understand
their
significance,
it
is
critical
first
explore
molecular
mechanisms
underlying
formation
function.
Recent
studies
have
shed
light
on
biogenesis,
release,
biological
properties
migrasomes,
all
which
key
understanding
cell-to-cell
In
this
review,
we
provide
an
up-to-date
summary
migrasome
characterization,
activities
communication,
while
also
proposing
potential
new
functions
for
these
vesicles.
Язык: Английский
Migrasome: a novel insight into unraveling physiological and pathological function
Molecular Biology Reports,
Год журнала:
2025,
Номер
52(1)
Опубликована: Май 28, 2025
Язык: Английский
Role of Redox Homeostasis in the Communication Between Brain and Liver Through Extracellular Vesicles
Antioxidants,
Год журнала:
2024,
Номер
13(12), С. 1493 - 1493
Опубликована: Дек. 6, 2024
Extracellular
vesicles
(EVs)
are
small,
membrane-bound
particles
secreted
by
cells
into
the
extracellular
environment,
playing
an
increasingly
recognized
role
in
inter-organ
communication
and
regulation
of
various
physiological
processes.
Regarding
redox
homeostasis
context,
EVs
play
a
pivotal
propagating
mitigating
oxidative
stress
signals
across
different
organs.
Cells
under
release
containing
signaling
molecules
that
can
influence
status
distant
tissues.
starting
to
be
as
contributors
brain-liver
communication.
Therefore,
this
review,
we
show
how
imbalance
affect
brain
liver.
We
propose
mediators
axis.
Язык: Английский