Role of Redox Homeostasis in the Communication Between Brain and Liver Through Extracellular Vesicles DOI Creative Commons

Javier Huete-Acevedo,

Cristina Mas‐Bargues,

Marta Arnal-Forné

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1493 - 1493

Published: Dec. 6, 2024

Extracellular vesicles (EVs) are small, membrane-bound particles secreted by cells into the extracellular environment, playing an increasingly recognized role in inter-organ communication and regulation of various physiological processes. Regarding redox homeostasis context, EVs play a pivotal propagating mitigating oxidative stress signals across different organs. Cells under release containing signaling molecules that can influence status distant tissues. starting to be as contributors brain-liver communication. Therefore, this review, we show how imbalance affect brain liver. We propose mediators axis.

Language: Английский

Migrasomes, critical players in intercellular communication DOI Creative Commons
Zhiyong Tan,

Chadanfeng Yang,

Shihui Fu

et al.

Cancer Cell International, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 25, 2025

Migrasomes are a newly discovered type of extracellular vesicle (EV) formed during cell migration, playing pivotal role in intercellular communication. These vesicles generated by retracting fibers migrating cells and encapsulate various molecules, such as proteins, lipids, RNA, allowing the transfer biochemical signals to neighboring cells. Current evidence suggests that migrasomes involved wide range physiological processes embryogenesis, angiogenesis, immune modulation, mitochondrial quality control. Moreover, implicated pathological conditions, including cancer metastasis, cardiovascular diseases, viral infections. To fully understand their significance, it is critical first explore molecular mechanisms underlying formation function. Recent studies have shed light on biogenesis, release, biological properties migrasomes, all which key understanding cell-to-cell In this review, we provide an up-to-date summary migrasome characterization, activities communication, while also proposing potential new functions for these vesicles.

Language: Английский

Citations

0
Role of Redox Homeostasis in the Communication Between Brain and Liver Through Extracellular Vesicles DOI Creative Commons

Javier Huete-Acevedo,

Cristina Mas‐Bargues,

Marta Arnal-Forné

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1493 - 1493

Published: Dec. 6, 2024

Extracellular vesicles (EVs) are small, membrane-bound particles secreted by cells into the extracellular environment, playing an increasingly recognized role in inter-organ communication and regulation of various physiological processes. Regarding redox homeostasis context, EVs play a pivotal propagating mitigating oxidative stress signals across different organs. Cells under release containing signaling molecules that can influence status distant tissues. starting to be as contributors brain-liver communication. Therefore, this review, we show how imbalance affect brain liver. We propose mediators axis.

Language: Английский

Citations

0