Community assembly of gut microbiomes in yolk sac fry of Atlantic salmon: host genetics, environmental microbiomes, and ecological processes
FEMS Microbiology Ecology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 17, 2025
In
this
study,
we
investigated
the
influence
of
host
genetics
and
environmental
microbiomes
on
early
gut
microbiome
Atlantic
salmon.
We
aimed
at
rearing
fish
in
either
r-
or
K-selected
environments,
where
r-selected
environment
would
be
expected
to
dominated
by
fast-growing
opportunistic
bacteria
thus
represent
more
detrimental
microbial
than
water.
Eggs
from
both
wild
aquaculture
strains
salmon
were
hatched
under
germ-free
conditions.
One
week
after
hatching
(wph),
flasks
inoculated
with
water
communities.
Three
wph,
no
effect
strain
observed.
r-selection
was
found
take
place
all
flasks,
including
added
Still,
differed
significantly
between
that
had
been
(Add-r
Add-K
respectively).
Lower
alpha
diversity
higher
abundances
Pseudomonas
observed
for
indicating
an
unfavorable
environment.
Selection
structured
microbiomes,
but
extensive
intraindividual
variation
explained
stochastic
processes
community
assembly.
The
also
Add-r
flasks.
they
similarities
assembly
communities
less
influenced
processes.
lower
growth
rates
probably
a
result
negative
host-microbe
interactions.
These
findings
highlight
importance
of,
challenges
related
to,
managing
when
cultivating
fish.
Язык: Английский
Fish as biological models: Implications for gut microbiota research in biomedical and aquaculture sciences
Aquaculture International,
Год журнала:
2025,
Номер
33(4)
Опубликована: Май 2, 2025
Язык: Английский
Interwoven processes in fish development: microbial community succession and immune maturation
PeerJ,
Год журнала:
2024,
Номер
12, С. e17051 - e17051
Опубликована: Март 27, 2024
Fishes
are
hosts
for
many
microorganisms
that
provide
them
with
beneficial
effects
on
growth,
immune
system
development,
nutrition
and
protection
against
pathogens.
In
order
to
avoid
spreading
of
infectious
diseases
in
aquaculture,
prevention
includes
vaccinations
routine
disinfection
eggs
equipment,
while
curative
treatments
consist
the
administration
antibiotics.
Vaccination
processes
can
stress
fish
require
substantial
farmer’s
investment.
Additionally,
antibiotics
not
specific,
they
may
be
effective
short
term,
have
major
drawbacks
long
term.
Indeed,
eliminate
bacteria
which
useful
host
promote
raising
antibiotic
resistance
beneficial,
commensal
but
also
pathogenic
bacterial
strains.
Numerous
publications
highlight
importance
plays
diversified
microbial
community
colonizing
(i.e.,
microbiota)
health
ultimately
survival
their
host.
This
review
targets
current
knowledge
bidirectional
communication
between
microbiota
during
development.
It
explores
extent
this
mutualistic
relationship:
one
hand,
effect
microbes
exert
ontogeny
fishes,
other
impact
critical
steps
development
recruitment
succession
throughout
life.
We
will
first
describe
its
gene
expression
fishes.
Secondly,
plurality
microbiotas
(depending
organism,
organ,
stage)
reviewed.
Then,
a
description
constant
interactions
fish’s
life
stages
discussed.
Healthy
allow
maturation
modulation
inflammation,
both
contribute
homeostasis.
Thus,
equilibrium
is
closely
linked
stability
examples
from
several
species
more
extensively
mechanisms
occurring
zebrafish
model
because
much
finely
described
species,
thanks
existing
mutants
precise
investigations.
conclude
how
conceptual
framework
associated
research
benefit
considering
relations
maturation.
More
precisely,
active
tolerance
earliest
enables
sustainable
establishment
complex
healthy
adult
Establishing
balanced
host-microbiota
interaction
avoids
triggering
deleterious
maintains
immunological
microbiological
Язык: Английский
A brain microbiome in salmonids at homeostasis
Science Advances,
Год журнала:
2024,
Номер
10(38)
Опубликована: Сен. 18, 2024
Ectotherms
have
peculiar
relationships
with
microorganisms.
For
instance,
bacteria
are
recovered
from
the
blood
and
internal
organs
of
healthy
teleosts.
However,
presence
microbial
communities
in
teleost
brain
has
not
been
proposed.
Here,
we
report
a
living
bacterial
community
salmonids
loads
comparable
to
those
spleen
1000-fold
lower
than
gut.
Brain
share
>50%
their
diversity
gut
communities.
Using
culturomics,
obtained
54
isolates
brains
trout.
Comparative
genomics
suggests
that
may
adaptations
for
niche
colonization
polyamine
biosynthesis.
In
natural
system,
Chinook
salmon
microbiomes
shift
juveniles
reproductively
mature
adults.
Our
study
redefines
physiological
between
This
symbiosis
endow
direct
mechanism
sense
respond
environmental
microbes.
Язык: Английский
Phage therapy minimally affects the water microbiota in an Atlantic salmon (Salmo salar) rearing system while still preventing infection
Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Ноя. 6, 2023
Excessive
usage
of
antibiotics
threatens
the
bacterial
diversity
in
microbiota
animals.
An
alternative
to
that
has
been
suggested
not
disturb
is
(bacterio)phage
therapy.
In
this
study,
we
challenged
germ-free
and
microbially
colonized
yolk
sac
fry
Atlantic
salmon
with
Flavobacterium
columnare
observed
mere
presence
a
protected
fish
against
lethal
infection.
We
then
investigated
effect
phage-
or
oxytetracycline
treatment
on
survival
rearing
water
community
characteristics
using
16S
rRNA
gene
amplicon
sequencing.
Phage
led
an
increased
F.
columnare-challenged
reduced
relative
amounts
pathogen
microbiota.
absence
columnare,
phage
did
affect
composition
α-diversity
phage's
host,
induced
minor
changes
composition,
without
affecting
α-diversity.
Surprisingly,
had
no
observable
reduce
abundance
water.
conclusion,
showed
prevents
mortality
while
negatively
microbiota,
thus
suggesting
may
be
suitable
antibiotics.
also
demonstrated
protective
fry.
Язык: Английский
The stability and composition of the gut and skin microbiota of Atlantic salmon throughout the yolk sac stage
Frontiers in Microbiology,
Год журнала:
2023,
Номер
14
Опубликована: Июль 6, 2023
The
bacterial
colonization
of
newly
hatched
fish
is
important
for
the
larval
development
and
health.
Still,
little
known
about
ontogeny
early
microbiota
fish.
Here,
we
conducted
two
independent
experiments
with
yolk
sac
fry
Atlantic
salmon
that
were
(1)
either
reared
conventionally,
eggs
as
only
source
bacteria
(egg-derived
microbiota;
EDM)
or
(2)
germ-free
re-colonized
using
lake
water
(lake-derived
LDM).
First,
characterized
gut
skin
at
6,
9,
13
weeks
post
hatching
based
on
extracted
RNA.
In
second
experiment,
exposed
to
high
doses
a
pathogen
commensal
isolate
sampled
DNA.
differed
strongly
between
EDM
LDM
treatments.
phyla
Proteobacteria,
Bacteroidetes,
Actinobacteria
dominated
microbiota,
which
was
found
temporarily
dynamic.
Interestingly,
more
stable,
both
replicate
rearing
flasks,
over
time.
Although
similar,
started
differentiate
during
stage,
several
before
consumed.
Addition
isolates
flasks
had
minor
effects
microbiota.
Язык: Английский
Feeding and water temperature modulate the potential activity of gut microbiota in greater amberjack juveniles (Seriola dumerili)
Frontiers in Marine Science,
Год журнала:
2023,
Номер
10
Опубликована: Сен. 12, 2023
Gut
microbial
communities
are
highly
dynamic
and
respond
to
factors
such
as
diet
host
metabolism.
However,
there
is
limited
knowledge
on
changes
in
gut
microbiota
during
the
daily
cycle.
To
investigate
how
interactions
between
feeding
water
temperature
affected
diurnal
dynamics
activity
of
microbiota,
we
analyzed
qualitative
quantitative
composition
feces
potentially
active
bacterial
community
along
a
day
cycle
greater
amberjack
juveniles
(
Seriola
dumerili
).
Bacterial
density
(based
qPCR
16S
rDNA)
was
relatively
stable
day.
In
contrast
rRNA)
increased
period
feeding,
reduced
pre-feeding
levels
four
hours
after
last
meal.
The
relative
potential
fish
varied
with
postprandial
time.
At
phylum
level
shift
from
Spirochaetes-dominated
morning
Proteobacteria
feeding.
lower
taxonomic
level,
i.e.
order,
dominated
by
Mycoplasmoidales,
which
maintained
throughout
all
treatments.
By
contrast,
for
absolute
at
order
peak
several
orders
6h
first
most
noticeable
increase
observed
Mycoplasmoidales.
Results
present
work
also
indicated
close
relation
effect
dynamics.
This
study
assessing
effects
rhythm
fish.
Feeding
main
driver
modulating
activity,
promoting
modulated
dynamics,
marked
time
scale.
addition,
results
indicate
that
analysis
provides
better
resolution
metabolically
community,
since
change
single
taxon
can
alter
taxa.
Язык: Английский
Damage on intestinal barrier function and Microbial detoxification of deoxynivalenol: A review1
Journal of Integrative Agriculture,
Год журнала:
2023,
Номер
23(8), С. 2507 - 2524
Опубликована: Ноя. 28, 2023
Deoxynivalenol
(DON)
is
a
mycotoxin
that
produced
by
various
species
of
Fusarium
and
ubiquitous
in
food
feed.
At
low
concentrations,
it
can
cause
metabolic
disorders
animals
humans
and,
at
high
lead
to
pathological
changes
the
body.
The
impact
DON
on
human/animal
health
animal
productivity
has
thus
attracted
great
deal
attention
around
world.
causes
severe
damage
intestine,
including
compromised
intestinal
barrier,
mucosal
damage,
weakened
immune
function,
alterations
gut
microbiota
composition.
These
effects
exacerbate
infections
inflammation
livestock
poultry,
posing
adverse
overall
health.
Furthermore,
research
into
biological
methods
for
detoxification
crucial
avenue
future
studies.
This
includes
utilization
adsorption,
enzymatic
degradation,
other
approaches
mitigate
DON's
impact,
offering
new
strategies
prevention
treatment
DON-induced
diseases.
Future
will
focus
identifying
highly
efficient
detoxifying
microorganisms
or
enzymes
reduce
levels
feed,
thereby
mitigating
its
risks
both
human
Язык: Английский
Phage therapy minimally affects the water microbiota in an Atlantic salmon (Salmo salar) rearing system while still preventing infection
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 4, 2023
Abstract
Excessive
usage
of
antibiotics
threatens
the
bacterial
diversity
in
microbiota
animals.
An
alternative
to
that
has
been
suggested
not
disturb
is
(bacterio)phage
therapy.
In
this
study,
we
challenged
germ-free
and
microbially
colonized
yolk
sac
fry
Atlantic
salmon
with
Flavobacterium
columnare
observed
mere
presence
a
protected
fish
against
lethal
infection.
We
then
investigated
effect
phage-or
oxytetracycline
treatment
on
survival
rearing
water
community
characteristics
using
16S
rRNA
gene
amplicon
sequencing.
Phage
led
an
increased
F.
columnare-
reduced
relative
amounts
pathogen
microbiota.
absence
,
phage
did
affect
composition
or
α-diversity
phage’s
host,
induced
minor
changes
composition,
without
affecting
α-diversity.
Surprisingly,
had
no
observable
reduce
abundance
water.
conclusion,
showed
prevents
mortality
while
negatively
microbiota,
thus
suggesting
may
be
suitable
antibiotics.
also
demonstrated
protective
fry.
Язык: Английский