Proteins Structure Function and Bioinformatics,
Год журнала:
2024,
Номер
92(8), С. 975 - 983
Опубликована: Апрель 15, 2024
Abstract
Pore‐forming
toxins
(PFTs)
are
proteins
that
form
lesions
in
biological
membranes.
Better
understanding
of
the
structure
and
function
these
will
be
beneficial
a
number
biotechnological
applications,
including
development
new
pest
control
methods
agriculture.
When
searching
for
pore
formers,
existing
sequence
homology‐based
fail
to
discover
truly
novel
with
low
identity
known
proteins.
Search
methodologies
based
on
protein
structures
would
help
us
move
beyond
this
limitation.
As
PFTs
is
very
limited,
it's
quite
challenging
identify
having
similar
using
computational
approaches
like
deep
learning.
In
article,
we
therefore
propose
sample‐efficient
graphical
model,
where
graph
first
constructed
according
consensus
secondary
structures.
A
semi‐Markov
conditional
random
fields
model
then
developed
perform
segmentation.
We
demonstrate
our
method
able
distinguish
structurally
even
absence
similarity
(pairwise
<
0.4)—a
feat
not
achievable
by
traditional
HMMs.
To
extract
interest
from
genome‐wide
database
further
study,
also
develop
an
efficient
framework
UniRef50
43
million
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2022,
Номер
10
Опубликована: Окт. 10, 2022
Current
crop
pest
control
strategies
rely
on
insecticidal
and
fungicidal
sprays,
plant
genetic
resistance,
transgenes
agricultural
practices.
However,
many
insects,
viruses,
fungi
have
no
current
means
of
or
developed
resistance
against
traditional
pesticides.
dsRNA
is
emerging
as
a
novel
sustainable
method
protection
an
alternative
to
chemical
The
successful
commercialisation
based
biocontrols
for
effective
management
requires
the
economical
production
large
quantities
combined
with
suitable
delivery
methods
ensure
RNAi
efficacy
target
pest.
A
number
exist
here
we
review
currently
employed
new
approaches
their
production.
Additionally,
highlight
potential
challenges
that
will
need
be
addressed
prior
widespread
adoption
alternatives
Abstract
During
the
last
decade,
sorghum
aphid
(
Melanaphis
sorghi
),
previously
identified
as
sugarcane
sacchari
became
a
serious
pest
of
sorghum,
spreading
to
all
sorghum‐producing
regions
in
United
States,
Mexico,
and
South
America,
where
crop
losses
50%–100%
have
been
reported.
Developing
cultivars
with
resistance
this
insect
is
most
sustainable
strategy
for
long‐term
management.
To
design
resistance,
comprehensively
understanding
mechanisms
underlying
survival,
host
plant
aphid–sorghum
interactions
critical.
In
review,
we
summarize
comprehensive
efforts
characterize
populations
well
their
interaction
plants
via
hormonal
pathways
that
trigger
various
genes
including
leucine
rich
repeats,
WRKY
transcription
factors,
lipoxygenases,
calmodulins,
others.
We
discuss
made
during
decade
identify
specific
genomic
candidate
confer
describe
recent
successes
potential
challenges
breeding
resistance.
Furthermore,
use
disruptive
technologies
like
high‐throughput
phenotyping,
artificial
intelligence,
or
machine
learning
developing
resistant
cultivars.
Integration
these
new
has
accelerate
development
novel
traits
durable
defend
against
genotype
development.
Journal of Cotton Research,
Год журнала:
2024,
Номер
7(1)
Опубликована: Сен. 3, 2024
Abstract
Cotton
plays
a
crucial
role
in
shaping
Indian
economy
and
rural
livelihoods.
The
cotton
crop
is
prone
to
numerous
insect
pests,
necessitating
insecticidal
application,
which
increases
production
costs.
advent
of
the
expression
Bacillus
thuringiensis
(Bt)
protein
has
significantly
reduced
burden
pest
without
compromising
environmental
or
human
health.
After
introduction
transgenic
cotton,
cultivated
area
expanded
22
million
hectares,
with
64%
increase
adoption
by
farmers
worldwide.
Currently,
Bt
accounts
for
93%
India.
However,
extensive
use
accelerated
resistance
development
pests
like
pink
bollworm.
Furthermore,
overreliance
on
broad-spectrum
pesticides,
favouring
emergence
secondary
significant
challenges.
This
emphasizes
urgent
necessity
developing
novel
management
strategies.
high-dose
refuge
strategy
was
initially
effective
managing
but
its
implementation
India
faced
challenges
due
misunderstandings
about
non-Bt
crops.
Although
gene
pyramiding
introduced
as
solution,
combining
mono
toxin
also
led
instances
cross-resistance.
Therefore,
there
need
further
exploration
biotechnological
approaches
manage
cotton.
Advanced
strategies,
such
sterile
release,
RNA
interference
(RNAi)-mediated
silencing,
stacking
RNAi,
genome
editing
using
clustered
regularly
interspaced
short
palindromic
repeats/CRISPR-associated
(CRISPR-Cas),
offer
promising
tools
identifying
genes
insects.
Additionally,
CRISPR-mediated
drives
biopesticides
present
potential
avenues
cultivation.
These
innovative
could
enhance
sustainability
efficacy
Egyptian Journal of Biological Pest Control,
Год журнала:
2024,
Номер
34(1)
Опубликована: Сен. 11, 2024
Abstract
Invasive
alien
insects
have
the
potential
to
pose
a
significant
threat
global
agriculture,
with
their
distinctive
traits
enabling
rapid
reproduction,
successful
adaptation
new
environments
and
high
distribution
capability.
These
pests
can
devastate
crops,
livestock,
biodiversity
ecosystem
functioning,
resulting
in
ecological
damage
substantial
economic
losses.
Climate
change
plays
crucial
role
driving
invasion
of
these
pests,
creating
favorable
conditions
for
development,
negatively
impacting
biodiversity.
Among
invasive
insects,
fall
armyworm
(FAW)
(
Spodoptera
frugiperda
)
(JE
Smith)
(Lepidoptera:
Noctuidae)
has
emerged
as
major
pest
species,
causing
yield
losses
maize
cropping
outside
his
native
range.
Initially,
reliance
on
pesticides
control
proved
ineffective
led
pesticide
resistance.
Significant
progress
been
made
implementing
integrated
management
(IPM)
strategies
that
integrate
agro-ecological
biological
approaches.
This
review
article
focuses
compilation
IPM
methods,
combining
practices
agents
such
parasitoids
viruses,
effective
FAW.
Approaches
intercropping,
agronomic
practices,
use
viruses
shown
promising
results
controlling
provides
insights
into
recommendations
suggestions
sustainable
FAW
using
or
combination.
Insects,
Год журнала:
2025,
Номер
16(3), С. 261 - 261
Опубликована: Март 3, 2025
Life
tables
are
indispensable
in
IPM,
offering
an
analysis
of
insect
population
dynamics.
These
record
survival
rates,
fecundity,
and
other
parameters
at
various
developmental
stages,
enabling
the
identification
key
factors
that
affect
numbers
prediction
growth
trajectories.
This
review
discusses
application
life
agricultural
pest
management,
including
assessment
control
capacity
natural
enemies,
evaluation
biological
agents,
screening
insect-resistant
plant
species.
In
vector
control,
used
to
evaluate
transmission
risks,
model
dynamics,
interfere
with
cycles
insects.
For
invasive
pests,
help
us
monitor
dynamics
predict
future
sizes.
chemical
assist
evaluating
fitness
costs
pesticide
resistance,
guiding
insecticide
selection,
optimizing
timing.
final
section,
we
explore
research
directions,
emphasizing
potential
integrating
new
technologies
such
as
genomics,
ethology,
satellite
remote
sensing
enhance
table
improve
IPM
strategies.
