Genetics and Molecular Biology,
Год журнала:
2024,
Номер
47(3)
Опубликована: Янв. 1, 2024
In
South
America,
Tambaqui
(Colossoma
macropomum)
stands
as
the
primary
target
for
aquaculture,
yet
breeding
programs
this
Amazon
native
species
are
in
their
early
stages.
While
high-density
single
nucleotide
polymorphism
(SNP)
arrays
pivotal
aquaculture
breeding,
costs
can
be
prohibitive
non-
or
semi-industrial
species.
To
overcome
this,
a
cost-effective
approach
involves
developing
low-density
SNP
followed
by
genotype
imputation
to
higher
densities.
study,
1K
array
tambaqui
was
created
and
validated,
offering
balance
between
quantity
genome
representativity.
The
accuracy
from
various
densities
medium-density
evaluated,
with
density
demonstrating
best
trade-off
(accuracy
of
0.93).
This
subset
further
utilized
construct
commercial
through
Agriseq™
targeted
genotyping-by-sequencing,
validated
192
DNA
samples,
affirming
its
high
quality
genotyping
tambaqui.
array,
genome-wide
coverage
polymorphism,
emerges
an
effective
tool
exploring
genetic
variation
within
diverse
populations.
Population
analyses
using
panel
proved
efficient
characterization
sampled
broodstocks,
making
it
valuable
resource
improvement
targeting
The
innovations
of
the
"Omics
Era"
have
ushered
in
significant
advancements
genetic
improvement
agriculturally
important
animal
species
through
transforming
genetics,
genomics
and
breeding
strategies.
These
were
often
coordinated,
part,
by
support
provided
over
30
years
1993-2023
National
Research
Support
Project
8
(NRSP8,
Animal
Genome
Program,
NAGRP)
affiliate
projects
focused
on
enabling
genomic
discoveries
livestock,
poultry,
aquaculture
species.
parallel
advances
demand
strategic
planning
future
research
priorities.
This
paper,
as
an
output
from
May
2023
Aquaculture
Genomics,
Genetics,
Breeding
Workshop,
provides
updated
status
resources
for
United
States
species,
highlighting
major
achievements
emerging
Finfish
shellfish
genome
omics
enhance
our
understanding
architecture
heritability
performance
production
traits.
Workshop
identified
present
aims
genomics/omics
to
build
this
progress:
(1)
advancing
reference
assembly
quality;
(2)
integrating
multi-omics
data
analysis
traits;
(3)
developing
collection
integration
phenomics
data;
(4)
creating
pathways
applying
information
across
industries;
(5)
providing
training,
extension,
outreach
application
phenome.
focuses
should
emphasize
collection,
artificial
intelligence,
identifying
causative
relationships
between
genotypes
phenotypes,
establishing
apply
tools
industries,
expansion
training
programs
next-generation
workforce
facilitate
sciences
into
operations
productivity,
competitiveness,
sustainability.
collective
vision
with
focus
highlighted
priorities
is
intended
continued
advancement
genomics,
genetics
community
industries.
Critical
challenges
ahead
include
practical
analytical
frameworks
beyond
academic
communities
that
require
collaborative
partnerships
academia,
government,
industry.
scope
review
encompasses
use
applications
study
aquatic
animals
cultivated
human
consumption
settings
throughout
their
life-cycle.
Aquaculture,
Год журнала:
2024,
Номер
583, С. 740589 - 740589
Опубликована: Янв. 17, 2024
Genomics
is
increasingly
applied
in
breeding
programmes
for
farmed
fish
and
shellfish
species
around
the
world.
However,
current
applications
do
not
include
information
on
genome
functional
activity,
which
can
enhance
opportunities
to
predict
relationships
between
genotypes
phenotypes
hence
increase
accuracy
of
selection.
Here,
we
review
prospects
improving
aquaculture
practises
through
uptake
genomics
data
light
EU
Horizon
2020
project
AQUA-FAANG:
‘Advancing
European
Aquaculture
by
Genome
Functional
Annotation’.
This
consortium
targeted
six
major
aquaculture,
producing
thousands
genomic
datasets
from
samples
representing
embryos
mature
adults
both
sexes,
following
immunological
stimulation.
was
used
catalogue
activity
across
each
species,
revealing
transcribed
regions,
distinct
chromatin
states
regulatory
elements
impacting
gene
expression.
These
annotations
were
shared
as
open
Ensembl
browser
using
latest
reference
genomes
species.
AQUA-FAANG
offers
novel
identify
prioritize
causative
genetic
variants
responsible
diverse
traits
including
disease
resistance,
be
exploited
selective
breeding.
Such
knowledge
associated
resources
have
potential
improve
sustainability
boost
production
accelerating
gain
health
robustness
infection,
whilst
reducing
requirement
animal
testing.
We
further
outline
directions
advance
leverage
annotation
beyond
project.
Given
diversity
sectors
businesses,
incorporation
into
decisions
will
depend
technological
readiness
level
scale
operation,
with
cost-benefit
analysis
necessary
determine
most
profitable
approach
system.
Vavilov Journal of Genetics and Breeding,
Год журнала:
2024,
Номер
28(4), С. 456 - 462
Опубликована: Июль 11, 2024
Genomic
selection
is
a
technology
that
allows
for
the
determination
of
genetic
value
varieties
agricultural
plants
and
animal
breeds,
based
on
information
about
genotypes
phenotypes.
The
measured
breeding
(BV)
breeds
in
relation
to
target
trait
stages
be
thoroughly
planned
parent
forms
suitable
crossing
chosen.
In
this
work,
BLUP
method
was
used
assess
149
Russian
introgression
lines
(4
measurements
each
variety
or
line,
596
phenotypic
points)
spring
wheat
according
content
seven
chemical
elements
grain
–
K,
Ca,
Mg,
Mn,
Fe,
Zn,
Cu.
quality
evaluation
values
assessed
using
cross-validation,
when
sample
randomly
divided
into
five
parts,
one
which
chosen
as
test
population.
following
average
Pearson
correlation
were
obtained
predicting
concentration
trace
elements:
K
0.67,
Ca
0.61,
Mg
0.4,
Mn
0.5,
Fe
0.38,
Zn
0.46,
Cu
0.48.
Out
35
models
studied,
p-value
below
nominal
significant
threshold
(p-value
<
0.05)
28
models.
For
11
models,
after
correction
multiple
testing
0.001).
four
out
two
had
adjusted
testing.
30
showed
best
varietal
296.43,
785.11
4.87
mg/kg
higher,
respectively,
than
results
show
relevance
application
genomic
even
such
limited-size
samples.
are
assessing
these
characteristics.
