AIDS Care,
Год журнала:
2024,
Номер
36(9), С. 1358 - 1368
Опубликована: Июнь 11, 2024
Post-COVID
conditions
(long
COVID)
are
defined
as
COVID
symptoms
persisting
28
days
post-initial
infection.
The
limited
research
available
on
the
prevalence
and
experiences
of
post-COVID
among
persons
with
HIV
(PWH)
indicates
potential
increased
risk
for
conditions.
purpose
this
study
was
to
characterize
prevalence,
symptom
clustering,
impact,
factors
PWH.
Data
come
from
COVID-19
survey,
conducted
a
sub-study
DC
Cohort
Longitudinal
Study,
an
ongoing
over
12,000
PWH
living
in
Washington,
DC.
Survey
data
were
matched
electronic
medical
record
data.
Prevalence
estimates
multivariable
logistic
regression
analyses
calculated
comparing
those
without
46%
no
significant
differences
demographic
or
measures.
Those
history
asthma
more
likely
report
symptoms.
Among
conditions,
81%
reported
three
initial
Retired/disabled
compared
employed
(aOR
=
2.37,
95%
CI
1.06,
5.33).
significantly
activities
daily
living.
Programs
needed
address
long-term
impact
European Journal of Pain,
Год журнала:
2025,
Номер
29(5)
Опубликована: Апрель 5, 2025
ABSTRACT
Background
Even
though
many
post‐COVID
pain
risk
factors
have
been
identified,
little
is
known
about
the
predictive
profiles
of
these
for
development
pain.
Methods
Data
was
collected
from
two
separate
questionnaires
assessing
demographics,
pre‐existing
medical
comorbidities,
history,
and
experience.
Socioeconomic
data
COVID‐19
RT‐PCR
test
results
were
Danish
registries.
The
study
cohort
(
n
=
68,028)
stratified
into
groups
reporting
pre‐COVID
9090)
no
55,938).
Forward‐selection
prediction
models
employed
to
identify
predictor
in
full
(Model
1)
with
2)
without
3)
58
potential
factors.
Results
Model
1
achieved
a
5‐fold
cross‐validated
AUC
(cvAUC)
0.68.
Use
medication,
stress,
high
income,
age,
female
gender,
weight
top
predictors
contributing
97%
model
performance.
2
(cvAUC
0.69)
identified
use
breathing
pain,
height,
physical
activity,
as
98.6%
3
0.65)
weight,
higher
education,
activity
98.5%
Height
unique
2,
while
being
income
3.
Conclusions
highlights
important
predictors,
further
research
needed
describe
detail.
may
apply
understanding
post‐viral
sequelae
after
other
viral
infections.
Significance
Statement
explorative
investigates
ability
battery
potentially
associated
This
article
presents
interest
survivors
will
contribute
patient
that
might
develop
conditions
provide
first
step
towards
focused
clinical
research.
Oxford University Press eBooks,
Год журнала:
2025,
Номер
unknown, С. 23 - 40
Опубликована: Фев. 20, 2025
Abstract
This
chapter
places
the
COVID-19
pandemic
in
its
historical
context
and
estimates
global
impact
variation
by
country.
We
consider
dynamic
interplay
between
social
position,
lifelong
health,
pandemic,
addressing
(1)
why
men
were
more
likely
to
get
severe
but
women
had
worse
mental
health
a
higher
risk
of
long
COVID;
(2)
inequalities
ethno-racial
socioeconomic
factors
exacerbated
during
pandemic;
(3)
effects
for
older
people,
response
younger
people.
Continued
follow-up
longitudinal
studies
will
reveal
long-term
consequences,
including
possible
critical
or
sensitive
periods
with
age
at
exposure.
Life
course
epidemiology
should
focus
on
consequences
infectious
diseases,
exacerbation
inequalities,
research
infrastructure
necessary
assess
implications
population
health.
Journal of General Virology,
Год журнала:
2023,
Номер
104(11)
Опубликована: Ноя. 10, 2023
The
recent
coronavirus
disease
2019
(COVID-19)
pandemic
was
caused
by
severe
acute
respiratory
syndrome
2
(SARS-CoV-2).
COVID-19
is
characterized
distress,
multiorgan
dysfunction
and,
in
some
cases,
death.
virus
also
responsible
for
post-COVID-19
condition
(commonly
referred
to
as
‘long
COVID’).
SARS-CoV-2
a
single-stranded,
positive-sense
RNA
with
genome
of
approximately
30
kb,
which
encodes
26
proteins.
It
has
been
reported
affect
multiple
pathways
infected
cells,
resulting,
many
the
induction
‘cytokine
storm’
and
cellular
senescence.
Perhaps
because
it
an
virus,
replicating
largely
cytoplasm,
effect
SARS-Cov-2
on
stability
DNA
damage
responses
(DDRs)
received
relatively
little
attention.
However,
now
becoming
clear
that
causes
DNA,
shown
presence
micronuclei,
repair
foci
increased
comet
tails
cells.
This
review
considers
evidence
indicating
how
instability,
deregulates
cell
cycle
targets
specific
components
DDR
pathways.
significance
virus’s
ability
cause
senescence
considered,
are
implications
instability
patients
suffering
from
long
COVID.
AIDS Care,
Год журнала:
2024,
Номер
36(9), С. 1358 - 1368
Опубликована: Июнь 11, 2024
Post-COVID
conditions
(long
COVID)
are
defined
as
COVID
symptoms
persisting
28
days
post-initial
infection.
The
limited
research
available
on
the
prevalence
and
experiences
of
post-COVID
among
persons
with
HIV
(PWH)
indicates
potential
increased
risk
for
conditions.
purpose
this
study
was
to
characterize
prevalence,
symptom
clustering,
impact,
factors
PWH.
Data
come
from
COVID-19
survey,
conducted
a
sub-study
DC
Cohort
Longitudinal
Study,
an
ongoing
over
12,000
PWH
living
in
Washington,
DC.
Survey
data
were
matched
electronic
medical
record
data.
Prevalence
estimates
multivariable
logistic
regression
analyses
calculated
comparing
those
without
46%
no
significant
differences
demographic
or
measures.
Those
history
asthma
more
likely
report
symptoms.
Among
conditions,
81%
reported
three
initial
Retired/disabled
compared
employed
(aOR
=
2.37,
95%
CI
1.06,
5.33).
significantly
activities
daily
living.
Programs
needed
address
long-term
impact
