Association of prognostic nutritional index with the presence and all-cause mortality of rheumatoid arthritis: the National Health and Nutrition Examination Survey 2003–2018

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Ноя. 26, 2024

The prognostic nutritional index (PNI) is a comprehensive measure of individual immune and status. This study aimed to evaluate the role PNI in presence mortality rheumatoid arthritis (RA). used data participants aged ≥ 40 years from National Health Nutrition Examination Survey (NHANES) 2003–2018. was calculated using serum albumin lymphocyte count. relationship between prevalence RA among patients assessed logistic Cox regression models. Nonlinear associations were explored restricted cubic splines (RCS). Of 18,245 (mean 55.4 years, 49% female), 1901 had RA, whom (480/1899, 25%) died during median follow-up period 84 months. inversely associated with likelihood having (odds ratio = 0.97, 95% confidence interval [CI]: 0.95–0.98). Compared whose lowest quartile, those other quartiles reduced by 21-38% (Ptrend <0.01). analysis revealed an inverse association all-cause (hazard 0.95, 95%CI: 0.91–0.99). An L-shaped observed turning points occurring around mean value PNI. significantly before plateaued afterwards. In middle-aged older adults, there RA.

Язык: Английский

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Association between body roundness index and osteoarthritis: a cross-sectional analysis of NHANES 2011–2018

Frontiers in Nutrition, Год журнала: 2024, Номер 11

Опубликована: Окт. 31, 2024

The objective of this study was to investigate the potential association between body roundness index (BRI) and risk osteoarthritis (OA) in US adults.

Язык: Английский

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The comprehensive relationship between combined anti-inflammatory and healthy diets and all-cause mortality in rheumatoid arthritis: results from NHANES 2003–2018

Arthritis Research & Therapy, Год журнала: 2024, Номер 26(1)

Опубликована: Дек. 23, 2024

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disorder. Diet recognized as modifiable factor that may influence inflammation and potentially accelerate RA progression. Nevertheless, the effects of diverse dietary patterns their combined impact on progression long-term mortality remain inadequately understood. This study examined association between in patients with RA, focusing Healthy Eating Index (HEI-2015) Dietary Inflammatory (DII) evaluating effects. The analysis included 2,069 from National Health Nutrition Examination Survey (NHANES) spanning 2003–2018. Weighted multi-variable Cox regression models estimated relationship DII, HEI-2015, patterns, all-cause RA. Linear associations were analyzed using restricted cubic splines (RCS). factors associated identified through Least Absolute Shrinkage Selection Operator (LASSO) method, subgroup sensitivity analyses conducted to strengthen findings. Participants had median age 59 years (IQR: 48–69), 42.1% male. Adjusting for potential confounders, hazard ratio (HR) individuals adhering healthy anti-inflammatory opposed unhealthy pro-inflammatory was 0.70 (95% CI: 0.53–0.92; adjusted P = 0.01; trend 0.02). In weighted DII higher quartiles showed no significant risk difference lowest quartiles. LASSO-Cox model 12 components predictive an AUC 0.749 (0.682–0.815) at 1 year, 0.763 (0.724–0.802) 3 years, 0.783 (0.749–0.802) 5 0.868 (0.712–0.938) all death events. Kaplan-Meier revealed low-risk group exhibited significantly lower compared high-risk (P < 0.001). These findings suggest combining HEI-2015 score correlates reduced among supporting modification strategy prevent premature this population.

Язык: Английский

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Effect of Whole Sesame Seeds on the Expression of Key Genes in Monocytes of Dairy Goats

Опубликована: Янв. 1, 2024

Язык: Английский

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Effect of whole sesame seeds on the expression of key genes in monocytes of dairy goats

Small Ruminant Research, Год журнала: 2024, Номер 238, С. 107333 - 107333

Опубликована: Июль 31, 2024

Язык: Английский

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