Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk DOI Creative Commons
Amna Ghith, Reza Maleki, Luke E. Grzeskowiak

и другие.

Biomolecules, Год журнала: 2025, Номер 15(3), С. 325 - 325

Опубликована: Фев. 24, 2025

Breastmilk is a complex biological fluid containing over thousand bioactive proteins, lipids, cells and small molecules that provide nutrition immunological protection for infants children. The composition of breastmilk unique to each individual can also vary within individuals according breastfeeding duration, maternal health, time day, other factors. As such, the be considered “fingerprint” could interrogated identify biomarkers breast health disease. However, accurate quantification components in remains significant challenge. Approaches such as immunoassays mass spectrometry have been largely applied study blood or fluids require validation optimisation before these techniques used accurately quantify compounds breastmilk. Development protocols specific should carried out with high precision, confidence, sensitivity. This review explores challenges opportunities associated different components.

Язык: Английский

Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk DOI Creative Commons
Amna Ghith, Reza Maleki, Luke E. Grzeskowiak

и другие.

Biomolecules, Год журнала: 2025, Номер 15(3), С. 325 - 325

Опубликована: Фев. 24, 2025

Breastmilk is a complex biological fluid containing over thousand bioactive proteins, lipids, cells and small molecules that provide nutrition immunological protection for infants children. The composition of breastmilk unique to each individual can also vary within individuals according breastfeeding duration, maternal health, time day, other factors. As such, the be considered “fingerprint” could interrogated identify biomarkers breast health disease. However, accurate quantification components in remains significant challenge. Approaches such as immunoassays mass spectrometry have been largely applied study blood or fluids require validation optimisation before these techniques used accurately quantify compounds breastmilk. Development protocols specific should carried out with high precision, confidence, sensitivity. This review explores challenges opportunities associated different components.

Язык: Английский

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