Heliyon,
Год журнала:
2023,
Номер
9(3), С. e14149 - e14149
Опубликована: Фев. 28, 2023
Pharmaceutical
companies
worldwide
are
scrambling
to
develop
new
ways
combat
cancer
and
microbiological
pathogens.
The
goal
of
this
research
was
investigate
the
antibacterial,
anticancer,
apoptosis
effects
novel
niosomal
formulated
Persian
Gulf
Sea
cucumber
extracts
(SCEs).
methanolic
were
prepared
encapsulated
in
niosome
nanoparticles
using
thin-film
hydration.
compound
made
up
Span
60
Tween
blended
with
cholesterol
a
3:3:4
M
ratios.
Characterization
niosome-encapsulated
SCE
evaluated
by
scanning
electron
microscopy
transmission
microscopy.
disk
diffusion
method
microtiter
plates
used
antimicrobial
activity.
effect
on
cell
proliferation
induction
studied
MTT
Annexin
V,
respectively.
expression
apoptosis-related
genes,
including
Bax,
Fas,
Bak,
Bcl2,
quantitative
real-time
PCR.
Niosome-encapsulated
size
80.46
±
1.31
an
encapsulation
efficiency
79.18
0.23
formulated.
At
concentration
100
μg/ml,
greatest
correlated
Staphylococcus
aureus,
inhibition
zone
13.16
mm.
findings
study
revealed
that
all
strains
unable
produce
biofilms
at
μg/ml
(p
<
0.001).
survival
rate
cells
after
72
h
exposure
40
3.0%.
Encapsulated
niosomes
inhibited
progression
MCF-7
increasing
G0/G1
decreasing
S
phase
relative
G2/M
phase;
as
result,
it
activated
signaling
pathway
led
69.12
1.2%
tumor
proapoptotic
genes
results
indicate
sea
species
from
promising
source
natural
chemicals
antibacterial
anticancer
properties,
paving
path
for
marine
products
be
discovered.
This
is
first
demonstration
contains
that,
according
their
specific
characteristics,
boost
antitumor
iScience,
Год журнала:
2024,
Номер
27(12), С. 111339 - 111339
Опубликована: Ноя. 7, 2024
As
the
global
population
continues
to
grow,
so
does
demand
for
longer,
healthier
lives
and
environmentally
responsible
choices.
Consumers
are
increasingly
drawn
naturally
sourced
products
with
proven
health
wellbeing
benefits.
The
marine
environment
presents
a
promising
yet
underexplored
resource
cosmetics
industry,
offering
bioactive
compounds
potential
safe
biocompatible
ingredients.
This
manuscript
provides
comprehensive
overview
of
organisms
production,
highlighting
marine-derived
their
applications
in
skin/hair/oral-care
products,
cosmeceuticals
more.
It
also
lays
down
critical
safety
considerations
addresses
methodologies
sourcing
compounds,
including
harvesting,
biorefinery
concept,
use
systems
biology
enhanced
product
development,
relevant
regulatory
landscape.
review
is
enriched
by
three
case
studies:
design
macroalgal
skincare
Iceland,
establishment
microalgal
spin-off
Italy,
utilization
proteins
cosmeceutical
applications.
The Science of The Total Environment,
Год журнала:
2022,
Номер
839, С. 156230 - 156230
Опубликована: Май 26, 2022
Marine
eutrophication
is
a
pervasive
and
growing
threat
to
global
sustainability.
Macroalgal
cultivation
promising
circular
economy
solution
achieve
nutrient
reduction
food
security.
However,
the
location
of
production
hotspots
not
well
known.
In
this
paper
potential
macroalgae
high
commercial
value
was
predicted
across
Baltic
Sea
region.
addition,
limitation
within
adjacent
macroalgal
farms
investigated
suggest
optimal
site-specific
configuration
farms.
The
Saccharina
latissima
largely
driven
by
salinity
highest
yields
are
expected
in
westernmost
areas
where
>23.
direct
interactive
effects
light
availability,
temperature,
concentrations
regulated
changes
Ulva
intestinalis
Fucus
vesiculosus.
western
southern
exhibited
farming
for
these
species,
with
also
eastern
Sea.
did
induce
significant
limitation.
spatial
propagation
caused
less
than
100-250
m.
Higher
distances
were
found
low
water
exchange
(e.g.
offshore
Proper)
smaller
Gulf
Riga).
generated
maps
provide
most
sought-after
input
support
blue
growth
initiatives
that
foster
sustainable
development
situ
loads
Heliyon,
Год журнала:
2023,
Номер
9(3), С. e14149 - e14149
Опубликована: Фев. 28, 2023
Pharmaceutical
companies
worldwide
are
scrambling
to
develop
new
ways
combat
cancer
and
microbiological
pathogens.
The
goal
of
this
research
was
investigate
the
antibacterial,
anticancer,
apoptosis
effects
novel
niosomal
formulated
Persian
Gulf
Sea
cucumber
extracts
(SCEs).
methanolic
were
prepared
encapsulated
in
niosome
nanoparticles
using
thin-film
hydration.
compound
made
up
Span
60
Tween
blended
with
cholesterol
a
3:3:4
M
ratios.
Characterization
niosome-encapsulated
SCE
evaluated
by
scanning
electron
microscopy
transmission
microscopy.
disk
diffusion
method
microtiter
plates
used
antimicrobial
activity.
effect
on
cell
proliferation
induction
studied
MTT
Annexin
V,
respectively.
expression
apoptosis-related
genes,
including
Bax,
Fas,
Bak,
Bcl2,
quantitative
real-time
PCR.
Niosome-encapsulated
size
80.46
±
1.31
an
encapsulation
efficiency
79.18
0.23
formulated.
At
concentration
100
μg/ml,
greatest
correlated
Staphylococcus
aureus,
inhibition
zone
13.16
mm.
findings
study
revealed
that
all
strains
unable
produce
biofilms
at
μg/ml
(p
<
0.001).
survival
rate
cells
after
72
h
exposure
40
3.0%.
Encapsulated
niosomes
inhibited
progression
MCF-7
increasing
G0/G1
decreasing
S
phase
relative
G2/M
phase;
as
result,
it
activated
signaling
pathway
led
69.12
1.2%
tumor
proapoptotic
genes
results
indicate
sea
species
from
promising
source
natural
chemicals
antibacterial
anticancer
properties,
paving
path
for
marine
products
be
discovered.
This
is
first
demonstration
contains
that,
according
their
specific
characteristics,
boost
antitumor
