Different processing methods and pharmacological effects of Atractylodis Rhizoma

Chinese Journal of Natural Medicines, Год журнала: 2024, Номер 22(8), С. 756 - 768

Опубликована: Авг. 1, 2024

Язык: Английский

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Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes

Molecules, Год журнала: 2024, Номер 29(6), С. 1379 - 1379

Опубликована: Март 20, 2024

The rhizomes of the genus Atractylodes DC. consist various bioactive components, including sesquiterpenes, which have attracted a great deal research interest in recent years. In present study, we reviewed previously published literatures prior to November 2023 on chemical structures, biosynthetic pathways, and pharmacological activities sesquiterpenoids from this via online databases such as Web Science, Google Scholar, ScienceDirect. Phytochemical studies led identification more than 160 notably eudesmane-type sesquiterpenes. Many been demonstrated, particularly anticancer, anti-inflammatory, antibacterial antiviral activities. This review presents updated, comprehensive categorized information phytochemistry pharmacology sesquiterpenes DC., with aim offering guidance for future exploitation utilization active ingredients genus.

Язык: Английский

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Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway

Cell Biochemistry and Biophysics, Год журнала: 2024, Номер 82(3), С. 2747 - 2757

Опубликована: Июль 8, 2024

Язык: Английский

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Fu-Zheng-Xuan-Fei formula promotes macrophage polarization and Th17/Treg cell homeostasis against the influenza B virus (Victoria strain) infection

Journal of Ethnopharmacology, Год журнала: 2023, Номер 312, С. 116485 - 116485

Опубликована: Апрель 10, 2023

Fu-Zheng-Xuan-Fei formula (FF) is a prescription that has been clinically used through the basic theory of traditional Chinese medicine (TCM) for treating viral pneumonia. Although FF possesses prominent clinical therapeutic effect, seldom pharmacological studies have reported on its anti-influenza B virus (IBV) activity. Influenza an acute infectious respiratory disease caused by influenza virus, which high annual morbidity and mortality worldwide. With global decline in COVID-19 control, infection rate gradually increasing. Therefore, it great importance to develop novel drugs effective treatment virus. Apart from conventional antiviral drugs, TCM widely China. studying mechanism can facilitate scientific development TCM. Madin-Darby canine kidney cells (MDCK) BALB/c mice were infected with IBV, was added evaluate anti-IBV effects both vitro vivo Western blotting, immunofluorescence, flow cytometry, pathological assessment. It found exhibited anti-viral activity against IBV vitro, while inducing macrophage activation promoting M1 polarization. In addition, effectively regulated signal transducer activator transcription (STAT) signaling pathway-mediated Th17/Treg balance improve lung tissue damage infection-induced inflammation. The findings provided basis infection. This study shows potentially drug

Язык: Английский

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Xiao-Er-Kang-Du capsules regulate autophagy against the influenza B virus (Victoria strain) through the mTOR/ULK1/Beclin1/VPS34 pathway

Journal of Ethnopharmacology, Год журнала: 2024, Номер 337, С. 118872 - 118872

Опубликована: Окт. 2, 2024

Язык: Английский

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