Cited by Xiao-Er-Kang-Du capsules regulate autophagy against the influenza B virus (Victoria strain) through the mTOR/ULK1/Beclin1/VPS34 pathway

Different processing methods and pharmacological effects of Atractylodis Rhizoma DOI

Dongmei Guo, Kang Xu,

Qianyun Wan

et al.

Chinese Journal of Natural Medicines, Journal Year: 2024, Volume and Issue: 22(8), P. 756 - 768

Published: Aug. 1, 2024

Language: Английский

Citations

Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes DOI

Zhengyi Qu,

Hongqun Liu, Zhenghai Zhang

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(6), P. 1379 - 1379

Published: March 20, 2024

The rhizomes of the genus Atractylodes DC. consist various bioactive components, including sesquiterpenes, which have attracted a great deal research interest in recent years. In present study, we reviewed previously published literatures prior to November 2023 on chemical structures, biosynthetic pathways, and pharmacological activities sesquiterpenoids from this via online databases such as Web Science, Google Scholar, ScienceDirect. Phytochemical studies led identification more than 160 notably eudesmane-type sesquiterpenes. Many been demonstrated, particularly anticancer, anti-inflammatory, antibacterial antiviral activities. This review presents updated, comprehensive categorized information phytochemistry pharmacology sesquiterpenes DC., with aim offering guidance for future exploitation utilization active ingredients genus.

Language: Английский

Citations

Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway DOI

Yunxia Li, Jinzhong Liu, Fang Li

et al.

Cell Biochemistry and Biophysics, Journal Year: 2024, Volume and Issue: 82(3), P. 2747 - 2757

Published: July 8, 2024

Language: Английский

Citations

Fu-Zheng-Xuan-Fei formula promotes macrophage polarization and Th17/Treg cell homeostasis against the influenza B virus (Victoria strain) infection DOI

Yan Xiao,

Jinxin Zhang, Xiangyu Zhu

et al.

Journal of Ethnopharmacology, Journal Year: 2023, Volume and Issue: 312, P. 116485 - 116485

Published: April 10, 2023

Fu-Zheng-Xuan-Fei formula (FF) is a prescription that has been clinically used through the basic theory of traditional Chinese medicine (TCM) for treating viral pneumonia. Although FF possesses prominent clinical therapeutic effect, seldom pharmacological studies have reported on its anti-influenza B virus (IBV) activity. Influenza an acute infectious respiratory disease caused by influenza virus, which high annual morbidity and mortality worldwide. With global decline in COVID-19 control, infection rate gradually increasing. Therefore, it great importance to develop novel drugs effective treatment virus. Apart from conventional antiviral drugs, TCM widely China. studying mechanism can facilitate scientific development TCM. Madin-Darby canine kidney cells (MDCK) BALB/c mice were infected with IBV, was added evaluate anti-IBV effects both vitro vivo Western blotting, immunofluorescence, flow cytometry, pathological assessment. It found exhibited anti-viral activity against IBV vitro, while inducing macrophage activation promoting M1 polarization. In addition, effectively regulated signal transducer activator transcription (STAT) signaling pathway-mediated Th17/Treg balance improve lung tissue damage infection-induced inflammation. The findings provided basis infection. This study shows potentially drug

Language: Английский

Citations

Xiao-Er-Kang-Du capsules regulate autophagy against the influenza B virus (Victoria strain) through the mTOR/ULK1/Beclin1/VPS34 pathway DOI

Yan Cao, Jing Han,

Yan Xiao

et al.

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 337, P. 118872 - 118872

Published: Oct. 2, 2024

Language: Английский

Citations