A novel alkali and thermotolerant protease from Aeromonas spp. retrieved from wastewater DOI Creative Commons

Najmeh Sodagar,

Razieh Jalal, Mohsen Fathi Najafi

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 29, 2024

Abstract Enzymes are integral to numerous industrial processes, with a growing global demand for various enzyme types. Protease enzymes, in particular, have proven be cost-effective, stable, and compatible alternatives traditional chemical processes both environmental applications. In this study, an alkaline protease-producing strain of Aeromonas spp. was isolated from wastewater treatment plant Iran. The protease production confirmed by culturing the on casein agar medium. bacterium identified through morphological, biochemical, 16 S rRNA sequencing analyses. optimal culture medium bacterial growth obtained using peptone, salt, yeast extract, galactose, CaCl₂ at initial pH 8. Maximum achieved after 20 h incubation 40 °C. To partially purify enzyme, supernatant first centrifuged, precipitated ammonium sulfate, followed dialysis. Zymography revealed one type during growth. purified exhibited activity 8.5 maximum stability 9. optimum temperature observed 50 °C, 100% residual retained 1 0 effect metal ions assessed, revealing that KCl induced most significant effects ( p < 0.0001) activity. Chemical amino acid modifiers inhibitors, such as EDTA, DEPSI, IAA, did not exhibit inhibition. contrast, PMSF HNBB significantly reduced activity, suggesting could classified serine protease. also demonstrated high presence 2% SDS, showing no signs inactivation. optimum, thermal stability, resistance SDS produced particularly promising characteristics warrant further investigation. Based preliminary tests enzyme’s characteristics, can recommended applications, pending studies.

Язык: Английский

Engineering Bacillus licheniformis as industrial chassis for efficient bioproduction from starch DOI
Jiang Zhu, Min Liu,

Jianling Kang

и другие.

Bioresource Technology, Год журнала: 2024, Номер 406, С. 131061 - 131061

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

4

Characterization of a novel levansucrase produced by Bacillus subtilis LG-4 isolated from traditional natto for biosynthesis of prebiotic lactosucrose DOI

Hangyu Hu,

Jing Liu, Gege Hu

и другие.

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106292 - 106292

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Hemp Seed Protein Hydrolysate Enriched with γ-Aminobutyric Acid and Peptides by Microbial Bioconversion DOI Creative Commons

Yun-Ho Park,

Joo-Hyeong Kim,

Dong‐Min Shin

и другие.

Fermentation, Год журнала: 2024, Номер 10(9), С. 483 - 483

Опубликована: Сен. 17, 2024

Hemp seed protein (HSP), a by-product of hemp oil processing, was converted into functional ingredient enriched with γ-aminobutyric acid (GABA) and peptides through two-step microbial fermentation process. To enhance peptide free amino production from HSP, it hydrolyzed using alkaline protease produced by Bacillus subtilis HA. The HSP at degree 40% 55 °C for 24 h, yielding pH 6.55, an acidity 1.22%, 205.45 mg% tyrosine equivalents. This process resulted in the low molecular-weight peptides. (<5000 Da) total content branched-chain acids (leucine, isoleucine, valine) were 6.78 mg/g 1.47 mg/g. Subsequently, hydrolysate optimized co-fermentation lactic bacteria presence 5% MSG 30 5 days. serial co-fermented exhibited GABA 33.98 viable bacterial count 9.51 log CFU/mL Lb. plantarum KS2020. process, combining proteolysis fermentation, not only increased but also promoted accumulation, positioning as promising candidate foods potential health benefits.

Язык: Английский

Процитировано

1

Composition and Essential Nutrients of Cyanobacterium Meal Produced from Spirulina (Arthrospira platensis) Fermented by Yeast on Small-Scale DOI Creative Commons

Amrih Prasetyo,

Isyana Khaerunnisa, Slamet Diah Volkandari

и другие.

Case Studies in Chemical and Environmental Engineering, Год журнала: 2024, Номер unknown, С. 100940 - 100940

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

0

Characterization of alkaline protease enzyme produced from marine yeast Candida orthopsilosis AKB-1 and its applications DOI
Anwesha Sarkar,

S. R. Anjukrishna,

K. V. Bhaskara Rao

и другие.

Folia Microbiologica, Год журнала: 2024, Номер unknown

Опубликована: Окт. 28, 2024

Язык: Английский

Процитировано

0

A novel alkali and thermotolerant protease from Aeromonas spp. retrieved from wastewater DOI Creative Commons

Najmeh Sodagar,

Razieh Jalal, Mohsen Fathi Najafi

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 29, 2024

Abstract Enzymes are integral to numerous industrial processes, with a growing global demand for various enzyme types. Protease enzymes, in particular, have proven be cost-effective, stable, and compatible alternatives traditional chemical processes both environmental applications. In this study, an alkaline protease-producing strain of Aeromonas spp. was isolated from wastewater treatment plant Iran. The protease production confirmed by culturing the on casein agar medium. bacterium identified through morphological, biochemical, 16 S rRNA sequencing analyses. optimal culture medium bacterial growth obtained using peptone, salt, yeast extract, galactose, CaCl₂ at initial pH 8. Maximum achieved after 20 h incubation 40 °C. To partially purify enzyme, supernatant first centrifuged, precipitated ammonium sulfate, followed dialysis. Zymography revealed one type during growth. purified exhibited activity 8.5 maximum stability 9. optimum temperature observed 50 °C, 100% residual retained 1 0 effect metal ions assessed, revealing that KCl induced most significant effects ( p < 0.0001) activity. Chemical amino acid modifiers inhibitors, such as EDTA, DEPSI, IAA, did not exhibit inhibition. contrast, PMSF HNBB significantly reduced activity, suggesting could classified serine protease. also demonstrated high presence 2% SDS, showing no signs inactivation. optimum, thermal stability, resistance SDS produced particularly promising characteristics warrant further investigation. Based preliminary tests enzyme’s characteristics, can recommended applications, pending studies.

Язык: Английский

Процитировано

0