Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 31, 2023
Abstract
Oxidative
stress
is
widely
involved
in
the
pathological
process
of
ischemic
stroke
and
ischemia-reperfusion.
Several
research
have
demonstrated
that
eliminating
or
reducing
oxidative
can
alleviate
changes
stroke.
However,
current
clinical
antioxidant
treatment
did
not
always
perform
as
expected.
This
bibliometric
aims
to
identify
trends,
topics,
hotspots
evolution
on
field
stroke,
find
potentially
strategies
future
treatment.
Relevant
publications
were
searched
from
Web
Science
(WOS)
Core
Collection
databases
(2001–2022).
VOSviewer
was
used
visualize
analyze
development
trends
hotspots.
In
number
increased
significantly
2001
2022.
China
USA
leading
countries
for
publication
output.
The
most
prolific
institutions
Stanford
University.
Journal
Cerebral
Blood
Flow
Metabolism
Stroke
cited
journals.
topics
this
include
inflammation
with
stress,
mitochondrial
damage
reperfusion
injury,
cognitive
impairment
basic
translation
stress.
Moreover,
"NLRP3
inflammasome",
"autophagy",
"mitophagy",
"miRNA",
"ferroptosis"
"signaling
pathway"
are
emerging
recent
years.
At
present,
multi-target
regulation
focusing
multi-mechanism
crosstalk
has
progressed
across
period,
while
challenges
come
transformation
application.
New
detection
technology
new
nanomaterials
expected
integrate
into
better.
Heliyon,
Год журнала:
2024,
Номер
10(4), С. e26377 - e26377
Опубликована: Фев. 1, 2024
Short-chain
fatty
acids
(SCFAs)
are
thought
to
play
a
key
role
in
the
microbe-gut-brain
axis
and
involve
pathogenesis
of
variety
neurological
diseases.
This
study
aimed
identify
research
hotspots
evolution
trends
SCFAs
central
nervous
diseases
(CNS)
examine
current
trends.
Diabetology & Metabolic Syndrome,
Год журнала:
2024,
Номер
16(1)
Опубликована: Фев. 15, 2024
Abstract
Background
Diabetes
is
a
metabolic
disorder
posing
global
threat
to
health.
Many
scholars
are
dedicated
developing
non-pharmacological
therapies,
and
mindfulness
intervention
among
the
potentially
effective
approaches.
Due
rapid
increase
in
relevant
research
recent
years,
along
with
diverse
focus
interventions
used
studies,
it
has
become
challenging
for
practitioners
quickly
comprehend
key
features
of
this
field
directions
worth
paying
attention
to.
Bibliometric
analysis,
response,
can
help
understand
identify
points
interest.
Methods
Publications
related
diabetes
from
establishment
Web
Science
Core
Collection
(WOSCC)
September
2023
were
searched.
We
employed
four
bibliometric
techniques:
General
Analysis
Publications,
Collaborative
Network
Analysis,
Co-citation
Keyword
Analysis.
The
CiteSpace
6.1.R
was
analyze
literature
strongest
citation
bursts,
while
VOSviewer
1.6.13
provide
visualizations
publicly
available
data
by
analyzing
co-citations
or
co-authorship
affiliations.
Results
found
total
387
articles.
results
indicate
that
on
topic
been
steadily
increasing
over
time.
United
States
top
producer
publications,
Tilburg
University
being
institution
publishes
most
journal
“Mindfulness”
highest
publication
count.
In
collaborative
network
emerged
as
main
hub
cooperation
field,
contributing
182
articles
5872
citations.
“Diabetes
Care”
frequently
cited
played
central
role.
keyword
analysis
revealed
researchers
have
shown
strong
interest
how
affect
mental
health
diabetic
individuals.
Additionally,
there
studying
elderly
groups
exploring
impact
diseases.
These
areas
currently
priorities.
Conclusion
Our
findings
demonstrate
current
trend
hotspots
offer
some
future
research.
Frontiers in Pharmacology,
Год журнала:
2025,
Номер
16
Опубликована: Апрель 11, 2025
Background
Ischemic
stroke
(IS)
remains
a
leading
global
cause
of
mortality
and
chronic
disability.
Neutrophil
extracellular
traps
(NETs),
recently
identified
as
neutrophil-derived
structures
that
trap
neutralize
pathogens,
have
increasingly
drawn
attention
for
their
involvement
in
IS
pathogenesis.
Despite
surge
related
research,
no
bibliometric
analyses
yet
examined
the
knowledge
framework
trends
within
this
emerging
field.
Here,
we
conducted
systematic
analysis
to
map
research
landscape
identify
current
potential
hotspots
regarding
NETs
IS.
Methods
Relevant
literature
published
between
2014
2024
was
systematically
retrieved
from
Web
Science
Core
Collection
(WoSCC)
database.
Multiple
analytical
tools,
including
CiteSpace,
VOSviewer,
R
package
“bibliometrix,”
Python
scripts,
were
employed
explore
publication
trends,
academic
collaborations,
prominent
themes,
topics.
Results
Ninety-two
publications
eligible
assessment,
supplemented
by
an
additional
latent
Dirichlet
allocation
(LDA)-based
topic
4,504
documents.
China
(30
publications)
United
States
(23
emerged
countries
terms
output,
with
collaboration
networks
predominantly
centering
around
States.
Noteworthy
contributions
also
arose
European
institutions,
particularly
Katholieke
Universiteit
Leuven
Karolinska
Institutet.
The
authors
Desilles,
Jean-Philippe,
Ho-Tin-Noé,
Benoit,
Mazighi,
Mikael.
Journals
such
Stroke
,
Annals
Neurology
Nature
Communications
significantly
influenced
domain.
Three
main
emerged:
(1)
“promoting
effect
protein
arginine
deiminase
4
(PAD4)
NET
formation,”
(2)
“cell-free
DNA
biomarker
disease
diagnosis,”
(3)
“influence
platelets
thrombosis
on
NETs-related
diseases.”
Conclusion
Our
study
offers
extensive
overview
existing
evolving
trajectories
concerning
IS,
providing
researchers
clear
insights
into
future
investigative
directions.
Nevertheless,
our
has
limitations—including
dependence
single
database
(WoSCC),
restriction
English-language
publications,
inherent
constraints
LDA
methodology—that
merit
consideration
interpreting
these
findings.
World Journal of Gastroenterology,
Год журнала:
2023,
Номер
29(20), С. 3203 - 3215
Опубликована: Май 25, 2023
Crohn's
disease
represents
a
challenge
for
patients
concerned
with
the
modified
diet
regimen
as
well
practitioners
who
seek
best
nutritional
therapy.
can
alter
body's
ability
to
digest
food
and
absorb
nutrients,
resulting
in
severe
vitamin
deficiencies,
malnutrition
sometimes
life-threatening
complications.
However,
comprehensive
bibliometric
analysis
is
lacking
map
current
links
between
nutrition
terms
of
number
citations,
geographic
distribution
growth
trends
publications.To
introduce
state
research
hotspots
field
from
standpoint.We
searched
Scopus
database
selected
relevant
literature
on
that
met
inclusion
criteria.
We
analyzed
publication
by
using
video
object
segmentation
viewer
software.We
included
1237
publications.
The
documents
published
each
year
has
increased
steadily.
United
States
University
Otago,
Christchurch,
have
had
highest
productivity,
208
(16.81%)
29
(2.34%)
documents,
respectively.
"role
exclusive
enteral
complicated
disease"
"manipulation
gut
microbiota
key
target
were
major
areas
2016-2021,
they
could
be
extensively
investigated
future.
Meanwhile,
"malnutrition
appeared
an
area
attracted
more
attention
before
2016.This
first
knowledge
structure
regarding
over
past
two
decades.
results
provide
summary
identification
frontiers
disease-related
research,
which
may
used
resource
researchers
field.
Frontiers in Neuroscience,
Год журнала:
2023,
Номер
17
Опубликована: Июль 28, 2023
Diabetes-associated
cognitive
dysfunction
(DACD)
is
a
common
and
serious
complication
in
diabetes
has
high
impact
on
the
lives
of
both
individuals
society.
Although
number
research
focused
DACD
past
two
decades,
there
no
study
to
systematically
display
knowledge
structure
development
field.
Thus,
present
aimed
show
landscape
identify
emerging
trends
for
assisting
researchers
or
clinicians
grasping
domain
faster
easier
focusing
field.We
searched
Web
Science
database
all
DACD-related
studies
between
2000
2022.
Bibliometric
analysis
was
conducted
using
VOSviewer,
CiteSpace,
Histcite,
R
bibliometric
package,
revealing
most
prominent
research,
countries,
institutions,
authors,
journals,
co-cited
references,
keywords.A
total
4,378
records
were
selected
analysis.
We
found
that
volume
literature
increased
over
years.
In
terms
publications,
USA
ranked
first.
The
productive
institutions
University
Washington
Pittsburgh.
Furthermore,
Biessels
GJ
author.
Journal
Alzheimers
Disease,
Diabetes
Care,
Frontiers
Aging
Neuroscience
had
publications
this
keywords"dementia,"
"alzheimers-disease,"
"cognitive
impairment"
"diabetes"
are
main
keywords.
burst
keywords
recent
years
mainly
included
"signaling
pathway"
deficit."This
illustrated
advances
last
23
Current
findings
suggest
exploring
potential
mechanisms
effect
anti-diabetes
drugs
hotspots
Future
will
also
focus
targeted
act
signaling
pathway.
Translational Medicine Communications,
Год журнала:
2024,
Номер
9(1)
Опубликована: Март 2, 2024
Abstract
Background
Insulin
resistance
is
a
major
pathogenic
factor
that
plays
crucial
role
in
the
development
of
metabolic
syndrome
and
has
been
proposed
as
one
its
underlying
causes.
Most
diagnostic
criteria
for
do
not
directly
include
insulin
resistance.
Furthermore,
research
on
continues
to
provide
information
treatment
syndromes
related
health
conditions.
Therefore,
this
bibliometric
analysis
aimed
investigate
current
status
identify
possible
future
hotspots
area
by
analyzing
Scopus-based
studies.
Methods
To
collect
published
data
resistance,
study
used
Scopus
database
source
without
particular
starting
date
but
including
records
up
December
31,
2022.
The
gathered
documents
were
then
exported
VOSviewer
v.1.6.18
analyze
visualize
country
collaborations
areas
high
interest.
Results
presents
an
overview
1932
between
1988
2022,
focusing
Of
these
records,
77.33%
original
journal
articles,
while
13.30%
review
articles.
Additionally,
9.35%
fall
under
other
types
publication,
letters,
notes,
editorials.
United
States
came
out
top
with
463
items,
accounting
23.96%
contributions
field,
followed
Japan
second
place
119
items
(6.16%).
China
(
n
=
113,
5.85%)
Kingdom
ranked
third.
publications
focus
key
terms
pathogenesis
syndrome,
use
waist
circumference
clinical
indicator
evaluate
risk
association
oxidative
stress
pro-inflammatory
state.
Conclusions
This
first
findings
offer
comprehensive
global
perspective
carried
can
be
invaluable
research.