Integrating physiological and transcriptomic analyses at the single-neuron level DOI Creative Commons

Haruya Yagishita,

Takuya Sasaki

Neuroscience Research, Год журнала: 2024, Номер unknown

Опубликована: Май 1, 2024

Neurons generate various spike patterns to execute different functions. Understanding how these physiological neuronal are related their molecular characteristics is a long-standing issue in neuroscience. Herein, we review the results of recent studies that have addressed this by integrating and transcriptomic techniques. A sequence experiments, including vivo recording and/or labeling, brain tissue slicing, cell collection, analysis, identified gene expression profiles neurons at single-cell level, with activity recorded living animals. Although techniques still early stages, methodological idea principally applicable regions patterns. Accumulating evidence will contribute deeper understanding insights from molecules cells, circuits, behaviors.

Язык: Английский

Adaptive circuits for action and value information in rodent operant learning DOI Creative Commons
Alain Ríos, Kyohei Fujita, Yoshikazu Isomura

и другие.

Neuroscience Research, Год журнала: 2024, Номер unknown

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

1

Integrating physiological and transcriptomic analyses at the single-neuron level DOI Creative Commons

Haruya Yagishita,

Takuya Sasaki

Neuroscience Research, Год журнала: 2024, Номер unknown

Опубликована: Май 1, 2024

Neurons generate various spike patterns to execute different functions. Understanding how these physiological neuronal are related their molecular characteristics is a long-standing issue in neuroscience. Herein, we review the results of recent studies that have addressed this by integrating and transcriptomic techniques. A sequence experiments, including vivo recording and/or labeling, brain tissue slicing, cell collection, analysis, identified gene expression profiles neurons at single-cell level, with activity recorded living animals. Although techniques still early stages, methodological idea principally applicable regions patterns. Accumulating evidence will contribute deeper understanding insights from molecules cells, circuits, behaviors.

Язык: Английский

Процитировано

1