FORTITUDE OF NUTRITIONAL CAPACITY, TOTAL POLYPHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF DIVERSE VARIETIES OF ALMOND (PRUNUS DULCIS MILL. D.) FROM SELECTED AREAS DOI Open Access

M.K. SAEED,

N. Zahra,

Nazif Ullah

и другие.

Applied Ecology and Environmental Research, Год журнала: 2024, Номер 22(2), С. 1495 - 1508

Опубликована: Янв. 1, 2024

Natural antioxidant use has increased as a consequence of consumer desire for natural and organic foods.Almonds (Prunus dulcis Mill.D.) are an important food item both nutritionally medicinally.The health advantages attributed to these, the value-added products developed from them have been linked activities phenolic compounds in nuts.The nutritional characteristics, total contents, activity almond with brown skin without were examined current study.The findings facts support possibility using almonds sector they propose that significant source energy, protein, fiber, lipid.The results content ranged 240.6±3.2-295.5±4.2 232.3±2.8-278.4±3.6 mg GAE/100 g.The inhibition DPPH radical scavenging capacity varied over 37.60-65.09% 28.83-45.51%,without at concentration 5 mg/ml.The reducing power (absorbance 700 nm) increase all varieties however these higher varieties.This study showed excellent sources nutrients antioxidants potential value addition nutraceutical development.

Язык: Английский

Flurbiprofen Clubbed Schiff's Base Derivatives as Potent Anticancer Agents: In Vitro and In Silico Approach towards Breast Cancer DOI
Aftab Alam,

Faizullah Khan,

Najeeb Ur Rehman

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1321, С. 139743 - 139743

Опубликована: Авг. 29, 2024

Язык: Английский

Процитировано

4
The effect of different wall materials on the physicochemical properties and antioxidant activity of pomegranate peel polyphenols (PPP) microcapsules DOI
Zhi‐Hong Zhang,

Huiyue Wang,

Xinyang Han

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139958 - 139958

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Bioflavonoids: A Detailed Take on Their Extraction Methods, Stability, and Applications DOI
Debapriya Maitra, Bedaprana Roy, Abhijit Chaudhuri

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Mechanism of action of quercetin in regulating cellular autophagy in multiple organs of Goto-Kakizaki rats through the PI3K/Akt/mTOR pathway DOI Creative Commons
Zhiqun Guo, Jingyu Zhang,

M. Li

и другие.

Frontiers in Medicine, Год журнала: 2024, Номер 11

Опубликована: Авг. 15, 2024

Objective This experimental study investigated the protective function of quercetin on liver, spleen, and kidneys Goto-Kakizaki (GK) rats explores its mechanism action autophagy-related factors pathways. Materials methods GK were randomly divided into three groups: DM, DM + L-Que, H-Que, with age-matched Wistar serving as control group. The groups gavaged saline, quercetin-treated group was for 8 weeks each. Weekly blood glucose levels monitored. Upon conclusion experiment, samples gathered lipid hepatic renal analyses. histopathologic morphology deposition in examined. Disease-related targets identified using molecular docking network pharmacology analysis. Subsequently, immunohistochemical analysis performed, followed by Western blotting to evaluate proteins AKT/PI3K/mTOR pathway, well their phosphorylation levels. Results results showed that, compared group, exhibited significant increases glucose, serum liver kidney markers, fat vacuoles, inflammatory cell infiltration. Immunohistochemistry (IHC) indicated that reduced extensive expression AKT, P62, mTOR spleen diabetic rats. autophagy pathway-related proteins, such PI3K, P-PI3K, Akt, P-AKT, mTOR, P-mTOR, upregulated, while LC3A/LC3B, Beclin-1, Pink-1, Parkin downregulated. Conversely, a reduction injury markers decreasing necrosis, indicating has effects Additionally, P-mTOR downregulated, statistically correlations. Conclusion Quercetin markedly ameliorates damage rats, potentially through inhibition PI3K/Akt/mTOR promoting autophagy. research offers rationale therapeutic potential mitigating organ associated diabetes.

Язык: Английский

Процитировано

3
FORTITUDE OF NUTRITIONAL CAPACITY, TOTAL POLYPHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF DIVERSE VARIETIES OF ALMOND (PRUNUS DULCIS MILL. D.) FROM SELECTED AREAS DOI Open Access

M.K. SAEED,

N. Zahra,

Nazif Ullah

и другие.

Applied Ecology and Environmental Research, Год журнала: 2024, Номер 22(2), С. 1495 - 1508

Опубликована: Янв. 1, 2024

Natural antioxidant use has increased as a consequence of consumer desire for natural and organic foods.Almonds (Prunus dulcis Mill.D.) are an important food item both nutritionally medicinally.The health advantages attributed to these, the value-added products developed from them have been linked activities phenolic compounds in nuts.The nutritional characteristics, total contents, activity almond with brown skin without were examined current study.The findings facts support possibility using almonds sector they propose that significant source energy, protein, fiber, lipid.The results content ranged 240.6±3.2-295.5±4.2 232.3±2.8-278.4±3.6 mg GAE/100 g.The inhibition DPPH radical scavenging capacity varied over 37.60-65.09% 28.83-45.51%,without at concentration 5 mg/ml.The reducing power (absorbance 700 nm) increase all varieties however these higher varieties.This study showed excellent sources nutrients antioxidants potential value addition nutraceutical development.

Язык: Английский

Процитировано

2