Nigella
sativa,
commonly
referred
to
as
black
cumin
or
seed,
has
drawn
interest
due
possible
immunomodulatory
properties.Thymoquinone
is
one
of
the
bioactive
chemicals
found
in
N.
sativa
that
qualities
can
affect
immune
system.It
boost
cell
activity,
control
inflammatory
processes,
and
alter
generation
cytokines,
among
other
immunological
responses.Nigella
properties
may
be
related
its
capacity
proportion
T
lymphocytes
macrophages,
cells,
promoting
a
more
robust
well-balanced
response.Thymoquinone
also
been
linked
decreased
inflammation
oxidative
stress,
which
lends
credence
function.In
this
chapter,
potential
discussed.
Journal of Pharmacy and Pharmacology,
Год журнала:
2024,
Номер
77(1), С. 18 - 31
Опубликована: Авг. 21, 2024
The
study
aims
to
explore
the
potential
of
medicinal
plants
and
their
phytoconstituents
as
effective
inhibitors
coronavirus
disease
2019
(COVID-19),
caused
by
SARS-CoV-2
virus.
focus
is
on
investigating
specific
known
for
pharmacological
properties,
such
as:
antioxidant,
anti-inflammatory,
immunomodulatory
effects,
determine
viability
in
developing
COVID-19
treatments.
Global
health
and
economies
have
been
significantly
impacted
by
the
COVID-19
epidemic,
leading
to
a
race
find
effective
treatments
preventative
measures.
In
this
context,
natural
products
received
increased
attention
as
potential
source
of
antiviral
agents.
It
has
hypothesized
that
plant
Nigella
sativa
L.,
which
is
frequently
used
in
traditional
medicine,
capabilities
against
variety
viral
diseases.
This
chapter
attempts
study
possible
activities
N.
induced
SARS-CoV-2.
We
summarize
current
understanding
mechanism
action
infections,
including
its
effect
on
entry,
replication,
host
immune
response.
also
went
through
how
could
be
create
prevention
strategies.
Finally,
we
highlight
challenges
opportunities
research
derivatives
need
for
further
investigations
establish
their
clinical
efficacy
safety.
Overall,
suggests
bioactive
compounds
may
hold
promise
agents
SARS-CoV-2
shed
light
creation
innovative
therapies.
Nigella
sativa,
commonly
referred
to
as
black
cumin
or
seed,
has
drawn
interest
due
possible
immunomodulatory
properties.Thymoquinone
is
one
of
the
bioactive
chemicals
found
in
N.
sativa
that
qualities
can
affect
immune
system.It
boost
cell
activity,
control
inflammatory
processes,
and
alter
generation
cytokines,
among
other
immunological
responses.Nigella
properties
may
be
related
its
capacity
proportion
T
lymphocytes
macrophages,
cells,
promoting
a
more
robust
well-balanced
response.Thymoquinone
also
been
linked
decreased
inflammation
oxidative
stress,
which
lends
credence
function.In
this
chapter,
potential
discussed.
