Sanitarnyj vrač (Sanitary Doctor), Год журнала: 2024, Номер 10, С. 710 - 725

Опубликована: Сен. 30, 2024

More than five years have passed since the beginning of COVID-19 pandemic, but although fundamental role vitamin D’s effect on immune system is quite obvious to vast majority specialists, there are publications expressing a sharply negative attitude towards use D preparations for treatment patients infected with SARSCoV- 2. The purpose work: «generalization international experience issue deficiency in and need replenish it.» From archive National Library Medicine USA, containing 15,768 full versions articles incidence coronavirus population, we selected 49 presenting results clinical confirmed diagnosis COVID-19. Of these, 38 studies involving more 3,800 SARS-CoV-2 showed positive using as therapeutic agent (improvement inflammation markers, reduction artificial ventilation, length stay clinic, hospital mortality). In three articles, authors conclude that ineffective, they contain information about usefulness such use, differences intervention groups control not statistically significant. Seven indicate zero from preparations, one article says taking worsened condition critically ill patients. ratio positive, insignificant, trials (38:3:7:1) It significantly biased supplements reduce severity disease mortality infection. most common type drug used therapy cholecalciferol, calcidiol less often used, calcitriol ergocalciferol even (isolated cases been described). To date, has demonstrated greatest effectiveness complex COVID -19.

Язык: Английский