Vitamin D deficiency and the need to replenish it in COVID-19

Sanitarnyj vrač (Sanitary Doctor), Journal Year: 2024, Volume and Issue: 10, P. 710 - 725

Published: Sept. 30, 2024

More than five years have passed since the beginning of COVID-19 pandemic, but although fundamental role vitamin D’s effect on immune system is quite obvious to vast majority specialists, there are publications expressing a sharply negative attitude towards use D preparations for treatment patients infected with SARSCoV- 2. The purpose work: «generalization international experience issue deficiency in and need replenish it.» From archive National Library Medicine USA, containing 15,768 full versions articles incidence coronavirus population, we selected 49 presenting results clinical confirmed diagnosis COVID-19. Of these, 38 studies involving more 3,800 SARS-CoV-2 showed positive using as therapeutic agent (improvement inflammation markers, reduction artificial ventilation, length stay clinic, hospital mortality). In three articles, authors conclude that ineffective, they contain information about usefulness such use, differences intervention groups control not statistically significant. Seven indicate zero from preparations, one article says taking worsened condition critically ill patients. ratio positive, insignificant, trials (38:3:7:1) It significantly biased supplements reduce severity disease mortality infection. most common type drug used therapy cholecalciferol, calcidiol less often used, calcitriol ergocalciferol even (isolated cases been described). To date, has demonstrated greatest effectiveness complex COVID -19.

Language: Английский

Effect of vitamin D3 on antiphospholipid antibodies in hospitalized patients with moderate to severe COVID-19

Clinics, Journal Year: 2024, Volume and Issue: 79, P. 100474 - 100474

Published: Jan. 1, 2024

To investigate the effect of a single oral dose 200,000 IU vitamin D

Language: Английский

A Narrative Review of The Modulatory Effects of Vitamins in the Course of Covid-19 Disease

Deleted Journal, Journal Year: 2024, Volume and Issue: 29(2), P. 111 - 131

Published: May 1, 2024

Language: Английский