BIONATURE,
Год журнала:
2024,
Номер
44(2), С. 20 - 30
Опубликована: Авг. 26, 2024
Chronotype
is
morningness
and
eveningness
preference
of
humans.
The
human
biological
clock
primarily
entrained
by
sunlight
but
can
show
the
highly
flexible
phase-shifting
capacity
allows
a
person
to
adjust
new
time
zones,
shift
work,
temperature
changes,
seasonal
job
schedules,
social
obligations,
other
urgent
activities.
aim
current
study
was
identify
chronotype
interior
rural
residents
who
have
limited
access
electricity.
2117
healthy
subjects
(aged
between
6
75
years)
willingly
participated
in
study.
All
were
provided
with
biographical
information
sheets.
subjectively
assessed
using
Horne
Östberg
questionnaire
[1].Result
revealed
predominant
studied
population.
Evening-types
more
exposed
nighttime
artificial
light
as
well
screen
time.
In
addition,
body
surface
area
(BSA)
evening-types
also
significantly
higher
than
that
chronotypes.
Further
sleeping
waking
hours
delayed
evening-type
compared
morning-type
intermediate-type,
irrespective
work
days
free
days.
Present
provides
insights
populations
living
under
semi-modernized
conditions.
Absence
at
nights,
time,
less
facility
electricity
could
be
reason
for
among
eveningtypes
BSA
are
seems
susceptible
disturbed
sleep-wake
pattern.
Diagnostics,
Год журнала:
2025,
Номер
15(3), С. 327 - 327
Опубликована: Янв. 30, 2025
Wearable
devices
have
gained
increasing
attention
for
use
in
multifunctional
applications
related
to
health
monitoring,
particularly
research
of
the
circadian
rhythms
cognitive
functions
and
metabolic
processes.
In
this
comprehensive
review,
we
encompass
how
wearables
can
be
used
study
disease.
We
highlight
importance
these
as
markers
well-being
potential
predictors
outcomes.
focus
on
wearable
technologies
sleep
research,
medicine,
chronomedicine
beyond
domain
emphasize
actigraphy
a
validated
tool
monitoring
sleep,
activity,
light
exposure.
discuss
various
mathematical
methods
currently
analyze
actigraphic
data,
such
parametric
non-parametric
approaches,
linear,
non-linear,
neural
network-based
applied
quantify
non-circadian
variability.
also
introduce
novel
actigraphy-derived
markers,
which
personalized
proxies
status,
assisting
discriminating
between
disease,
offering
insights
into
neurobehavioral
status.
lifestyle
factors
physical
activity
exposure
modulate
brain
health.
establishing
reference
standards
measures
further
refine
data
interpretation
improve
clinical
The
review
calls
existing
tools
methods,
deepen
our
understanding
health,
develop
healthcare
strategies.
Biology of Sex Differences,
Год журнала:
2024,
Номер
15(1)
Опубликована: Янв. 12, 2024
Abstract
Rationale
Patients
with
anorexia
nervosa
(AN)
often
present
sleep
disorders
and
circadian
hormonal
dysregulation.
The
role
of
the
microbiota–gut–brain
axis
in
regulation
feeding
behavior
has
emerged
during
last
decades
but
its
relationships
rhythm
remains
poorly
documented.
Thus,
we
aimed
to
characterize
clock
genes
expression
peripheral
central
tissues
activity-based
mouse
model
(ABA),
as
well
dynamics
gut–microbiota
composition.
Methods
From
day
1
17,
male
female
C57Bl/6
mice
were
submitted
or
not
ABA
protocol
(ABA
control
(CT)
groups),
which
combines
a
progressive
limited
access
food
free
running
wheel.
At
fasted
CT
euthanized
after
either
resting
(EoR)
activity
(EoA)
phase
(
n
=
10–12
per
group).
Circadian
was
assessed
by
RT-qPCR
on
(liver,
colon
ileum)
(hypothalamic
suprachiasmatic
nucleus
SCN)
tissues.
Cecal
bacterial
taxa
abundances
evaluated
qPCR.
Data
compared
two-way
ANOVA
followed
post-tests.
Results
exhibited
lower
intake,
body
weight
loss
an
increase
diurnal
physical
that
differ
according
sex.
Interestingly,
SCN,
only
altered
Bmal1,
Per1,
Per2,
Cry1,
Cry2
).
In
intestinal
tract,
modification
also
more
marked
females
males.
For
instance,
ileum,
showed
alteration
Bmal1
,
Clock
Per1
Per2
Cry1
Rev-erbα
mRNA
levels,
while
mRNAs
affected
By
contrast,
liver,
markedly
males
response
ABA.
Finally,
variations
gut–bacteria
observed
both
sex-dependent
model.
Conclusions
This
study
shows
at
levels
occurs
addition,
our
data
underline
composition
are
sex-dependent.
Acta Oncologica,
Год журнала:
2025,
Номер
64, С. 222 - 228
Опубликована: Фев. 9, 2025
focused
on
patients
living
with
metastatic
cancer.
We
examined
the
feasibility
of
SleepNow
intervention
combining
cognitive
behavioral
therapy
for
insomnia
(CBT-I)
physical
exercise
in
men
prostate
cancer
(mPCa).
Patients/material
and
methods:
conducted
a
randomized
trial
under
treatment
castration
resistant
mPCa
(Insomnia
Severity
Index
[ISI]
score
≥
8).
Patients
were
1:1
to
either
or
usual
care.
is
manualized
12-week
program
consisting
bi-weekly
sessions
four
nurse-led
CBT-I.
care
received
no
treatment.
assessed
measured
objective
patient-reported
outcomes
at
baseline
3-months
follow-up.
Changes
both
groups
compared
using
Wilcoxon
test.
Results:
12
(5
7
control;
age
range
=
59–81
years,
mean
Gleason
7.75,
time
since
diagnosis
≈
years).
Intervention
reported
high
satisfaction,
all
attended
least
three
CBT-I
(75%)
completed
20
24
training
sessions.
The
group
showed
improvements
insomnia,
sleep
quality,
fatigue,
anxiety,
depression
health-related
quality-of-life
but
between-group
differences
not
statistically
significant.
Interpretation:
first
combine
nurse-delivered
was
acceptable
potentially
efficacious.
Our
results
are
important
targeting
interventions
growing
population
long
term
Frontiers in Psychology,
Год журнала:
2024,
Номер
15
Опубликована: Июнь 21, 2024
Physical
activity
has
been
shown
to
be
effective
in
treating
and
improving
anxiety
college
students.
However,
no
studies
have
conducted
examine
the
relationship
between
physical
students
through
mediating
factors
such
as
dietary
nutrition
lifestyle
habits.
Therefore,
aim
of
this
study
was
role
anxiety.
Physical Activity and Nutrition,
Год журнала:
2024,
Номер
28(2), С. 35 - 42
Опубликована: Июнь 30, 2024
[Purpose]
Circadian
clocks
are
evolved
endogenous
biological
systems
that
communicate
with
environmental
cues
to
optimize
physiological
processes,
such
as
the
sleep-wake
cycle,
which
is
nearly
related
quality
of
life.
Sleep
disorders
can
be
treated
using
pharmacological
strategies
targeting
melatonin,
orexin,
or
core
clock
genes.
Exercise
has
been
widely
explored
a
behavioral
treatment
because
it
challenges
homeostasis
in
human
body
and
affects
regulation
intervention
at
appropriate
time
day
induce
phase
shift
internal
clocks.
Although
exercise
strong
external
cue
for
resetting
circadian
clock,
therapy
sleep
remains
poorly
understood.[Methods]
This
review
focused
on
potential
by
tuning
clock.
We
used
scientific
paper
depositories,
including
Google
Scholar,
PubMed,
Cochrane
Library,
identify
previous
studies
investigated
effects
disorders.[Results]
The
exercise-induced
adjustment
depended
timing
individual
chronotypes.
Adjustment
through
scheduled
morning
exercises
appropriately
prescribed
individuals
delayed
disorders.
Individuals
advanced
synchronize
their
living
environment
performing
evening
exercises.
Exercise-induced
responses
affected
age,
sex,
current
fitness
conditions.[Conclusion]
Personalized
approaches
necessary
when
implementing
interventions
Expert Review of Neurotherapeutics,
Год журнала:
2025,
Номер
unknown, С. 1 - 16
Опубликована: Янв. 10, 2025
Introduction
In
Parkinson's
disease
(PD),
sleep–wake
problems
are
disease-related
symptoms
that
occur
throughout
the
day
and
have
a
negative
impact
on
patients'
quality
of
life
to
an
extent
is
equal
or
greater
than
typical
motor
symptoms.
Nutrients,
Год журнала:
2025,
Номер
17(2), С. 250 - 250
Опубликована: Янв. 11, 2025
Background/Objectives:
Sleep
disturbances
are
prevalent
among
pediatric
cancer
survivors
(PCSs)
and
their
caregivers,
often
leading
to
poorer
dietary
choices
reduced
physical
activity.
Additionally,
the
sleep
quality
health
behaviors
of
parents
children
can
affect
each
other.
This
study
examined
bi-directional
associations
between
PCSs
parents’
health-related
behaviors.
Methods:
127
parent–child
dyads
enrolled
in
a
behavioral
intervention
for
(Mage
=
11.04;
53.2%
female)
families
completed
Patient
Quality
Inventory
(PSQI)
USDA
Parent
or
Child
Food
Activity
Questionnaire
(FAQ).
Two
actor–partner
interdependence
models,
using
multi-level
modeling
adjusting
relevant
confounds,
estimated
bidirectional
dyad’s
composite
food
activity
quality.
Results:
After
controlling
partner
BMI
actor
age,
effect
children’s
PSQI
scores
on
parent’s
FAQ
was
statistically
significant
(β
−0.23,
p
0.036).
Poorer
associated
with
worse
parents.
Second,
after
race,
shown—greater
parental
better
PCS
−0.20,
0.041).
Conclusions:
Better
is
linked
improved
children,
while
poor
lower
The
findings
highlight
prospective
value
systems-focused
clinical
interventions
manage
promote
positive
PCS.
Frontiers in Cellular Neuroscience,
Год журнала:
2025,
Номер
19
Опубликована: Янв. 31, 2025
During
sleep,
several
crucial
processes
for
brain
homeostasis
occur,
including
the
rearrangement
of
synaptic
connections,
which
is
essential
memory
formation
and
updating.
Sleep
also
facilitates
removal
neurotoxic
waste
products,
accumulation
plays
a
key
role
in
neurodegeneration.
Various
neural
components
environmental
factors
regulate
influence
physiological
transition
between
wakefulness
sleep.
Disruptions
this
complex
system
form
basis
sleep
disorders,
as
commonly
observed
synucleinopathies.
Synucleinopathies
are
neurodegenerative
disorders
characterized
by
abnormal
build-up
α-synuclein
protein
aggregates
brain.
This
different
regions
leads
to
spectrum
clinical
manifestations,
hypokinesia,
cognitive
impairment,
psychiatric
symptoms,
neurovegetative
disturbances.
highly
prevalent
individuals
with
synucleinopathies,
they
not
only
affect
overall
well-being
patients
but
directly
contribute
disease
severity
progression.
Therefore,
it
develop
effective
therapeutic
strategies
improve
quality
these
patients.
Adequate
vital
health,
synucleinopathies
disrupting
patterns
must
be
taken
into
account.
In
context,
explore
physical
exercise
potential
non-pharmacological
intervention
manage
The
current
evidence
on
efficacy
programs
enhance
patient
population
discussed.
Sports,
Год журнала:
2025,
Номер
13(3), С. 80 - 80
Опубликована: Март 7, 2025
The
prevalence
of
impaired
mental
health
(MH)
has
increased
in
recent
decades.
aim
the
study
was
to
analyze
MH
amongst
registered
Spanish
golfers
using
GHQ-28
questionnaire.
A
cross-sectional
online
survey
carried
out
Spain
between
March
and
August
2024
a
self-administered
questionnaire
on
298
adult
participants.
participants
were
mainly
men
(75.1%)
over
60
years
age
(50.7%)
who
married
or
with
partner
(79.5%),
active
job
market
(56%).
Of
participants,
73.5%
reported
an
improvement
levels
attributed
game,
77.2%
recommended
golf
as
way
improve
MH.
6.7%
(95%
confidence
interval
[CI]:
4.1–10.2%).
Differences
found
according
(<=45
years:
28.6%;
46–60
5.0%
>60
4.0%;
p
=
0.001),
marital
status
(married
partner:
4.6%
vs.
other:
14.8%;
0.009)
time
play
(morning:
3.3%
10.3%;
0.015).
detected
low
these
results
indicated
that
such
playing
habits
characteristics
may
have
positive
impact
wellbeing
players.