Ketone monoester attenuates oxygen desaturation during weighted ruck exercise under acute hypoxic exposure but does not impact cognitive performance DOI Creative Commons

Tyler S. McClure,

Jeffrey J. Phillips,

Dawn Kernagis

и другие.

Experimental Physiology, Год журнала: 2024, Номер 109(10), С. 1768 - 1781

Опубликована: Авг. 27, 2024

Acute ingestion of exogenous ketone supplements in the form a (R)-3-hydroxybutyl (R)-3-hydroxybutyrate (R-BD R-βHB) monoester (KME) can attenuate declines oxygen availability during hypoxic exposure and might impact cognitive performance at rest response to moderate-intensity exercise. In single-blind randomized crossover design, 16 males performed assessments before with moderate exercise [2 × 20 min weighted ruck (∼22 kg) 3.2 km/h 10% incline] normobaric altitude chamber (4572 m, 11.8% O

Язык: Английский

Effects of heat load and hypobaric hypoxia on cognitive performance: a combined stressor approach DOI Creative Commons
Charelle Bottenheft, Eric L. Groen,

Douwe Mol

и другие.

Ergonomics, Год журнала: 2023, Номер 66(12), С. 2148 - 2164

Опубликована: Март 14, 2023

This study investigates how cognitive performance is affected by the combination of two stressors that are operationally relevant for helicopter pilots: heat load and hypobaric hypoxia. Fifteen participants were exposed to (1) no stressors, (2) load, (3) hypoxia, (4) combined Hypobaric hypoxia (13,000 ft) was achieved in a chamber. Heat induced increasing ambient temperature ∼28 °C. Cognitive measured using multitasks, vigilance task. Subjective physiological data (oxygen saturation, heart rate, core- skin temperature) also collected. Mainly caused decline. can be explained high subjective increased temperature, which takes away resources from tasks. Only arithmetic subtask sensitive whereby further decline addition load.Practitioner summary: Little known about multiple environmental interact. effects on performance. An additive effect found task, may attributed independent underlying mechanisms.

Язык: Английский

Процитировано

7

Continuous Physiological Monitoring of the Combined Exposure to Hypoxia and High Cognitive Load in Military Personnel DOI Creative Commons
Leonard A. Temme, Harrison L. Wittels, Michael J. Wishon

и другие.

Biology, Год журнала: 2023, Номер 12(11), С. 1398 - 1398

Опубликована: Ноя. 3, 2023

Military aviators endure high cognitive loads and hypoxic environments during flight operations, impacting the autonomic nervous system (ANS). The synergistic effects of these exposures on ANS, however, are less clear. This study investigated simultaneous mild hypoxia load ANS in military personnel. employed a two-factor experimental design. Twenty-four healthy participants aged between 19 45 years were exposed to (14.0% O2), normoxia (21.0% hyperoxia (33.0% O2). During each epoch (n = 5), continuously performed one 15 min 10 series simulated, in-flight tasks separated by 1 rest. Exposure sequences (hypoxia–normoxia normoxia–hyperoxia) 60 break. Heart rate (HR), heart variability (HRV), O2 saturation (SpO2) measured via an armband monitor (Warfighter MonitorTM, Tiger Tech Solutions, Inc., Miami, FL, USA). Paired independent t-tests used evaluate differences HR, HRV, SpO2 within exposure sequences. Survival analyses assess timing magnitude responses. Sympathetic (SNS) activity was highest (HR: +6.9 bpm, p 0.002; rMSSD: −9.7 ms, 0.003; SDNN: −11.3 SpO2: −8.4%, < 0.0000) appeared slightly decline with non-significant increases HRV. normoxia, SNS heightened, albeit non-significantly, 1, higher HR (68.5 bpm vs. 73.0 0.06), lower HRV (rMSSD: 45.1 ms 38.7 0.09 52.5 0.08), (−0.7% 0.05). In epochs 2–4, trended towards baseline values. Significant between-group observed. Hypoxia elicited significantly greater HRs (+5.0, 0.03), rMSSD (−7.1, SDNN (−8.2, (−1.4%, 0.002) compared normoxia. Hyperoxia augment parasympathetic reactivation reflected addition relative induced response personnel load. significant differential responses varying levels observed highlight importance monitoring multiple physiological parameters operations.

Язык: Английский

Процитировано

7

Intermittent Oxygen Fasting & Digital Technologies: from Antistress & Hormones Regulation to Wellbeing, Bliss & higher Mental States DOI Open Access
Athanasios Drigas, Eleni Mitsea,

Charalampos Skianis

и другие.

Technium BioChemMed, Год журнала: 2022, Номер 3(2), С. 55 - 72

Опубликована: Май 30, 2022

Low oxygen breathing has been the subject of considerable research in recent years. The present review aims to determine physiological and neuropsychological benefits low-oxygen training. Specifically, we explored ways low affects hormones, neurotransmitters growth factors responsible for neuroplasticity, higher cognition positive emotions. In addition, shed light on importance hypoxia expand conscious experience. Furthermore, investigate role digital technologies assisting hypoxic results showed that deprivation, under certain circumstances, beneficial effects cognition, mood consciousness. It was observed an increase factors, which are tissue repair regeneration. Hypoxia also found stimulate hormones pleasure, happiness, pain tolerance, socialization relaxation. Interestingly, people conditions more likely have transcendental experiences -even develop ‘superhuman’ abilities. Digital facilitate safe implementation training enabling users take control a powerful tool, is none other than breathing. Metacognition can help consciously safely manipulate their by moving themselves away from comfort zone exploring new pathways rewire brains plumb depths physical, cognitive, emotional spiritual potential.

Язык: Английский

Процитировано

11

Examining the Influence of Cognitive Load and Environmental Conditions on Autonomic Nervous System Response in Military Aircrew: A Hypoxia–Normoxia Study DOI Creative Commons
Harrison L. Wittels,

S. Howard Wittels,

Michael J. Wishon

и другие.

Biology, Год журнала: 2024, Номер 13(5), С. 343 - 343

Опубликована: Май 14, 2024

Executing flight operations demand that military personnel continuously perform tasks utilize low- and high-order cognitive functions. The autonomic nervous system (ANS) is crucial for regulating the supply of oxygen (O2) to brain, but it unclear how sustained loads different complexities may affect this regulation. Therefore, in current study, ANS responses low high hypoxic normoxic conditions were evaluated. present analysis used data from a previously conducted, two-factor experimental design. Healthy subjects (

Язык: Английский

Процитировано

2

Ketone monoester attenuates oxygen desaturation during weighted ruck exercise under acute hypoxic exposure but does not impact cognitive performance DOI Creative Commons

Tyler S. McClure,

Jeffrey J. Phillips,

Dawn Kernagis

и другие.

Experimental Physiology, Год журнала: 2024, Номер 109(10), С. 1768 - 1781

Опубликована: Авг. 27, 2024

Acute ingestion of exogenous ketone supplements in the form a (R)-3-hydroxybutyl (R)-3-hydroxybutyrate (R-BD R-βHB) monoester (KME) can attenuate declines oxygen availability during hypoxic exposure and might impact cognitive performance at rest response to moderate-intensity exercise. In single-blind randomized crossover design, 16 males performed assessments before with moderate exercise [2 × 20 min weighted ruck (∼22 kg) 3.2 km/h 10% incline] normobaric altitude chamber (4572 m, 11.8% O

Язык: Английский

Процитировано

2