Intermittent Oxygen Fasting & Digital Technologies: from Antistress & Hormones Regulation to Wellbeing, Bliss & higher Mental States

Technium BioChemMed, Journal Year: 2022, Volume and Issue: 3(2), P. 55 - 72

Published: May 30, 2022

Low oxygen breathing has been the subject of considerable research in recent years. The present review aims to determine physiological and neuropsychological benefits low-oxygen training. Specifically, we explored ways low affects hormones, neurotransmitters growth factors responsible for neuroplasticity, higher cognition positive emotions. In addition, shed light on importance hypoxia expand conscious experience. Furthermore, investigate role digital technologies assisting hypoxic results showed that deprivation, under certain circumstances, beneficial effects cognition, mood consciousness. It was observed an increase factors, which are tissue repair regeneration. Hypoxia also found stimulate hormones pleasure, happiness, pain tolerance, socialization relaxation. Interestingly, people conditions more likely have transcendental experiences -even develop ‘superhuman’ abilities. Digital facilitate safe implementation training enabling users take control a powerful tool, is none other than breathing. Metacognition can help consciously safely manipulate their by moving themselves away from comfort zone exploring new pathways rewire brains plumb depths physical, cognitive, emotional spiritual potential.

Language: Английский

---

Effects of heat load and hypobaric hypoxia on cognitive performance: a combined stressor approach

Ergonomics, Journal Year: 2023, Volume and Issue: 66(12), P. 2148 - 2164

Published: March 14, 2023

This study investigates how cognitive performance is affected by the combination of two stressors that are operationally relevant for helicopter pilots: heat load and hypobaric hypoxia. Fifteen participants were exposed to (1) no stressors, (2) load, (3) hypoxia, (4) combined Hypobaric hypoxia (13,000 ft) was achieved in a chamber. Heat induced increasing ambient temperature ∼28 °C. Cognitive measured using multitasks, vigilance task. Subjective physiological data (oxygen saturation, heart rate, core- skin temperature) also collected. Mainly caused decline. can be explained high subjective increased temperature, which takes away resources from tasks. Only arithmetic subtask sensitive whereby further decline addition load.Practitioner summary: Little known about multiple environmental interact. effects on performance. An additive effect found task, may attributed independent underlying mechanisms.

Language: Английский

---

Sleep loss effects on physiological and cognitive responses to systemic environmental hypoxia

Frontiers in Physiology, Journal Year: 2022, Volume and Issue: 13

Published: Dec. 12, 2022

In the course of their missions or training, alpinists, but also mountain combat forces and security services, professional miners, aircrew, aircraft glider pilots helicopter crews are regularly exposed to altitude without oxygen supplementation. At altitude, humans systemic environmental hypoxia induced by decrease in barometric pressure (<1,013 hPa) which decreases inspired partial (PIO 2 ), while fraction is constant (equal approximately 20.9%). Effects on occur gradually depend duration exposure level. From 1,500 m (response threshold), several adaptive responses offset effects hypoxia, involving respiratory cardiovascular systems, transport capacity blood. Fatigue cognitive sensory disorders usually observed from 2,500 (threshold prolonged hypoxia). Above 3,500 (the threshold for disorders), not completely compensated maladaptive individuals develop headache acute illness [Acute Mountain Sickness (AMS)]. The magnitude varies considerably between different physiological systems exhibits significant inter-individual variability. addition comorbidities, factors vulnerability still little known. They can be constitutive (genetic) circumstantial (sleep deprivation, fatigue, speed ascent.). particular, sleep loss, a condition that often encountered real-life settings, could have an impact hypoxia. this review, we report current state knowledge loss humans, with aim identifying possible consequences AMS risk cognition, as well value behavioral non-pharmacological countermeasures.

Language: Английский

---

Study of high-altitude cerebral edema using multimodal imaging

Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 13

Published: Jan. 26, 2023

Objective To analyze the brain imaging features of high-altitude cerebral edema (HACE) using computed tomography (CT) and multi-sequence magnetic resonance (MRI) to explore its injury characteristics. Materials methods We selected 30 patients with HACE diagnosed between January 2012 August 2022 as experimental group 60 dizziness on traveling from plain plateau or lower altitude higher in a short period time control group. collected general clinical data classified it according symptoms. In both groups, we then performed head CT MRI (T1WI, T2WI, FLAIR, DWI). Among them, nine were also scanned susceptibility-weighted (SWI). Finally, analyzed images. Results According symptoms, divided cases into 12 mild 18 severe cases. There was no significant difference sex, age, leukocyte, neutrophil, glucose content HACE. The sensitivity specificity diagnosis 100 100%, respectively, while 23.3 respectively. distribution range deep juxtacortical white matter significantly larger than ( p < 0.001). corpus callosum that = ADC value splenium 0.049). HACE, signal intensity DWI sequence conventional sequences FLAIR) 0.008, 0.025, respectively). seven showed bilateral corticospinal tract at thalamic level, SWI microbleeds (CMBs) five cases, especially callosum. Conclusions has more advantages evaluation sequence. is extensive, callosum, some CMBs may appear.

Language: Английский

---

Cocoa flavanols protect cognitive function, cerebral oxygenation, and mental fatigue during severe hypoxia

Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 135(2), P. 475 - 484

Published: July 20, 2023

We tested the hypothesis that ingestion of cocoa flavanols would improve cognition during acute hypoxia equivalent to 5,500 m altitude (partial pressure end-tidal oxygen = 45 mmHg). Using placebo-controlled double-blind trials, 12 participants ingested 15 mg·kg-1 90 min before completing cognitive tasks normoxia and either poikilocapnic or isocapnic carbon dioxide uncontrolled maintained at baseline value, respectively). Cerebral oxygenation was measured using functional near-infrared spectroscopy. Overall impaired by (main effect hypoxia, P 0.008). Cocoa improved a measure overall performance 4% compared with placebo (effect flavanols, 0.033) indicating change in from "low average" "average." The hypoxia-induced decrease cerebral two-fold greater than 0.005). Subjective fatigue increased 900% 0.004). 0.001) but not (mean improvement 1%; 0.72). Reaction time 8% further 11% 0.01). Our findings are first show flavanol-mediated improvements mood persist severe deprivation, conferring neuroprotective effect.NEW & NOTEWORTHY for exert hypoxia. Following flavanol ingestion, we observed cognition, oxygenation, subjective did suggesting possible interaction dioxide.

Language: Английский

---