Contrast Media & Molecular Imaging,
Год журнала:
2022,
Номер
2022(1)
Опубликована: Янв. 1, 2022
The
article
examines
the
expression
of
TC
and
TG
levels
in
initial
diagnosis
treatment
SCLC
patients
their
tie-in
with
prognosis.
Patients
are
included
case
set,
who
initially
treated
tumor
center
our
hospital
from
January
2020
to
2021
confirmed
by
histopathology
or
cytology
as
research
subjects.
80
healthy
volunteers
control
received
physical
examination.
All
enrolled
first-line
standard
plan,
clinical
data
all
inquired
through
medical
record
file
system
hospital.
At
treatment,
persons
measured
recorded
blood
biochemistry.
For
patients,
risk
factors
affecting
prognosis
progression-free
survival
include
newly
diagnosed
TC,
levels,
stage.
Combined
detection
can
be
used
indicators
predict
patients.
significantly
correlated
time.
It
is
worthy
application.
Journal of Affective Disorders,
Год журнала:
2022,
Номер
321, С. 167 - 181
Опубликована: Окт. 28, 2022
This
meta-analysis
and
systematic
review
aimed
to
evaluate
the
global
prevalence
risk
factors
of
mental
problems
(i.e.,
depression,
anxiety,
stress,
sleep
disorder,
posttraumatic
stress
disorder
(PTSD),
burnout,
psychological
distress,
suicidal
ideation)
among
medical
students
during
COVID-19
pandemic.
We
searched
PubMed,
Embase,
Web
Science,
psycARTICLES,
PsycINFO,
CNKI,
Wan
Fang
for
studies
on
from
January
1,
2020,
April
2022.
The
pooled
was
calculated
by
random-effect
models.
performed
a
narrative
identify
factors.
included
201
(N
=
198,000).
depression
(41
%,
95
%
CI,
37–45
%,),
anxiety
(38
%,95
34
%–42
%),
(34
27
(52
44
%–60
distress
(58
51
%–65
PTSD
22
%–46
ideation
(15
11
%–18
%)
burnout
25
%–50
high.
major
were
being
female,
junior
or
preclinical
students,
exposure
COVID-19,
academic
psychiatric
physical
disorders
history,
economic
trouble,
fear
education
impairment,
online
learning
infection,
loneliness,
low
activity,
social
support,
problematic
internet
smartphone
use,
young
age.
Most
cross-sectional.
Few
provided
reasonable
response
rate,
suggesting
potential
selection
bias.
study
demonstrated
high
calling
health
services.
Our
findings
are
valuable
college
authorities
high-risk
provide
targeted
intervention.
Arabian Journal of Chemistry,
Год журнала:
2022,
Номер
15(7), С. 103942 - 103942
Опубликована: Апрель 27, 2022
In
the
novel
SARS-CoV-2
(COVID-19)
as
a
global
emergency
event,
main
reason
of
cardiac
injury
from
COVID-19
is
angiotensin-converting
enzyme
2
(ACE2)
targeting
in
infection.
The
inhibition
ACE2
induces
an
increase
angiotensin
II
(Ang
II)
and
receptor
type
1
(AT1R)
leading
to
impaired
function
or
inflammatory
responses.
ethyl
acetate
fraction
Potentilla
reptans
L.
root
can
rescue
heart
dysfunction,
oxidative
stress,
arrhythmias
apoptosis.
Therefore,
isolated
components
P.
evaluated
identify
natural
anti-SARS-CoV-2
agents
via
molecular
docking.
silico
docking
study
were
carried
out
using
Auto
Dock
software
on
compounds
root.
protein
targets
selective
ACE
others
obtained
Protein
Data
Bank
(PDB).
best
binding
pose
between
amino
acid
residues
involved
active
site
was
discovered
Furthermore,
ADMET
properties
evaluated.
triterpenoids
showed
more
inhibitory
potential
than
catechin
both
domains.
They
nACE
domain,
especially
compound
5.
Also,
5
&
6
had
highest
affinity
toward
nACE,
cACE,
AT1R,
ACE2,
TNF-α
receptors.
Meanwhile,
3
activity
inhibit
TXA2.
Drug
likeness
analysis
that
passed
criteria
drug
Lipinski
rules.
current
depicted
cardioprotective
effect
infection
manipulation
II-induced
side
effects.
Frontiers in Psychology,
Год журнала:
2022,
Номер
13
Опубликована: Май 4, 2022
Servant
leadership
practice
honesty,
stewardship,
and
high
moral
standards
while
prioritizing
the
needs
of
subordinates.
The
concern
a
servant
is
to
support
others
put
first.
We
investigated
relationship
between
leadership,
psychological
safety,
knowledge
hoarding
in
accordance
with
social
learning
theory
survey
347
workers
across
56
teams.
results
this
study
illustrate
that
negatively
associated
positively
safety.
also
found
mastery
climate
moderated
hoarding.
This
highlights
theoretical
practical
implications
contribute
body
knowledge.
It
helps
organizations
presence
may
discourage
by
providing
psychologically
safe
climate.
Frontiers in Public Health,
Год журнала:
2022,
Номер
10
Опубликована: Март 18, 2022
The
COVID-19
pandemic
has
forced
higher
education
(HE)
to
shift
emergency
remote
teaching
(ERT),
subsequently
influencing
academic
belonging
and
social
integration,
as
well
challenging
students'
engagement
with
their
studies.
Frontiers in Public Health,
Год журнала:
2023,
Номер
11
Опубликована: Май 3, 2023
Background
Mental
health
challenges
have
emerged
worldwide
during
the
COVID-19
pandemic.
University
students
experienced
changes
in
their
lifestyles,
academic
life,
family
relationships,
earning
capacity,
and
support
systems.
This
study
explores
common
mental
university
coping
strategies
using
social
first
wave
of
lockdowns
Dhaka
city
2020.
By
learning
from
young
people’s
impacts
responses,
we
can
help
build
an
improved
strategy
for
future
events
this
magnitude.
Methods
A
qualitative
design
was
employed
to
conduct
20
in-depth
interviews
two
focus
group
discussions
with
purposively
selected
three
public
private
universities
five
key
informant
different
stakeholders.
We
used
inductive
reflexive
thematic
analysis
applied
six
phases
analysis.
Codes
retrieved
differently
prepared
codebooks
were
merged
compared
identify
themes
a
fair
interpretation
underlying
data.
Data
manually
indexed,
summarized,
interpreted
categorize
codes
into
sub-themes
leading
themes.
Results
Financial
constraints,
pressure,
resources
shortages,
losing
confidence,
relationship
breakup,
excessive
internet
dependency,
traumatic
experiences
challenged
conditions
unevenly
across
Expressed
well-being
ranged
anxiety,
stress,
depression
self-harm
suicidal
ideation.
Family
bonding
networking
appeared
as
robust
mechanisms
allow
cope
depression.
Partial
financial
subsidies,
soft
loans
purchase
electronic
resources,
faculty
members’
counseling,
sessional
counseling
contributed
minimizing
COVID-19.
Conclusion
is
still
not
resourced
area
Bangladesh.
Concentration
on
developing
strong
improving
increased
including
be
effective
assisting
burdens
pandemic
periods.
national
intervention
plan
should
immediately
designed
implemented
by
engaging
stakeholders
healthcare
professionals
establishing
centers
at
avoid
immediate
prolonged
negative
impacts.
Frontiers in Public Health,
Год журнала:
2023,
Номер
11
Опубликована: Май 9, 2023
Background
Students
were
at
an
increased
risk
for
elevated
mental
symptoms
during
the
first
year
of
COVID-19
pandemic
compared
to
pre-pandemic
levels.
As
universities
remained
closed
much
longer
than
anticipated,
burden
was
expected
persist
through
second
pandemic.
The
current
study
aimed
investigate
prevalence
distress
from
2019
2021
and
identify
factors
burden,
focusing
on
gender.
Methods
We
analyzed
three
cross-sectional
online
surveys
among
students
University
Mainz,
conducted
in
(
n
=
4,351),
2020
3,066),
1,438).
Changes
depressive
symptoms,
anxiety,
suicidal
ideation,
loneliness
calculated
using
Pearson's
chi-square
tests
analyses
variance.
Multiple
linear
regressions
yielded
associated
factors.
Results
proportion
with
clinically
relevant
significantly
higher
(38.9%
2020,
40.7%
2021),
(29.0%
2019).
Similarly,
more
reported
ideation
generalized
anxiety
a
peak
(2021).
level
2019,
high
p
<
0.001,
ηp2
0.142).
Female
diverse/open
gender,
being
single,
living
alone,
first-year
student
identified
as
Discussion
Mental
burdens
socio-demographic
pandemic-related
concerns.
Future
research
should
monitor
recovery
evaluate
need
psychosocial
support.
Frontiers in Psychiatry,
Год журнала:
2022,
Номер
13
Опубликована: Апрель 18, 2022
The
longitudinal
relationship
between
students'
pre-existing
adaptability
and
subsequent
sleep
mental
health
during
the
COVID-19
pandemic
has
not
been
studied.
present
study
examines
anxiety,
depression,
insomnia
after
lockdown
related
to
COVID-19.
5,235
university
students
participated
in
a
with
three
time
points.
Students
completed
Adaptability
Scale
before
outbreak
(October
2019;
Time
1),
Insomnia
Severity
Index
(ISI)
both
(April
2020;
2)
(March
2021;
3),
Anxiety
Depression
subscales
of
SCL-90
(at
1
SAS/SDS
2).
results
showed
that
self-reported
is
significantly
negatively
correlated
anxiety
depression
are
positively
insomnia.
Furthermore,
protects
from
directly
through
its
negative
depression.
This
sheds
light
on
internal
mechanisms
mediating
experience
challenging
circumstances.
Implications
for
curtailing
effects
stressful
events
by
improving
their
reducing
discussed.