Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1703 - 1703

Опубликована: Март 3, 2025

Background/Objectives: This systematic review outlines the neurocognitive outcomes and mechanisms of mindfulness-based cognitive therapy (MBCT) that influence subjective well-being. MBCT is a clinical intervention integrates with mindfulness practices to prevent depression relapses improve mental health. Methods: The focuses on effects brain structure changes, processes, emotional regulation, which are related improvements in A total 87 studies were included assess effectiveness MBCT. Results: Evidence from highlights reducing symptoms depression, anxiety, stress. was also shown enhance functions regulation across diverse populations. These findings point potential for induce neuroplastic changes widen applicability treatment variety disorders, calling further research into long-term benefits underlying neurobiological mechanisms. Conclusions: emphasizes bring about its study underlines need incorporate multidisciplinary measures by integrating psychology neuroscience comprehend comprehensively

Язык: Английский

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The Opioid Epidemic: a Crisis Disproportionately Impacting Black Americans and Urban Communities

Journal of Racial and Ethnic Health Disparities, Год журнала: 2022, Номер 10(4), С. 2039 - 2053

Опубликована: Сен. 6, 2022

Язык: Английский

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Delivery of biologics: Topical administration

Biomaterials, Год журнала: 2023, Номер 302, С. 122312 - 122312

Опубликована: Сен. 4, 2023

Biologics are unaffordable to a large majority of the global population because prohibitively expensive fermentation systems, purification and requirement for cold chain storage transportation. Limitations current production delivery systems biologics were evident during recent pandemic when <2.5% vaccines produced available low-income countries ∼19 million doses discarded in Africa due lack cold-chain infrastructure. Among FDA-approved since 2015, >90% delivered using invasive methods. While oral or topical drugs highly preferred by patients their affordability convenience, only two have been approved FDA 2015. A newly launched biologic costs ∼3% average cost injectable simplified regulatory approval process elimination fermentation, purification, storage/transportation. In addition, developing new product (∼$2.5 billion) has dramatically reduced through delivery. Topical unique advantage targeted high concentration protein drugs, without getting diluted circulating blood. However, very few FDA. Therefore, this review highlights advances proteins at early advanced stages human clinical trials chewing gums, patches sprays, nucleic acid directly, combination with, nanoparticles offers future directions.

Язык: Английский

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Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults

Social Cognitive and Affective Neuroscience, Год журнала: 2024, Номер 19(1)

Опубликована: Янв. 1, 2024

Abstract Aberrant levels of reward sensitivity have been linked to substance use disorder and are characterized by alterations in processing the ventral striatum (VS). Less is known about how subclinical relate striatal function during social rewards (e.g. positive peer feedback). Testing this relation critical for predicting risk development disorder. In pre-registered study, participants (N = 44) underwent fMRI while completing well-matched tasks that assess neural response monetary domains. Contrary our hypotheses, aberrant blunted relationship between activation receipt rewards, regardless domain. Moreover, exploratory whole-brain analyses showed unique relations temporoparietal junction. Psychophysiological interactions demonstrated associated with increased connectivity VS ventromedial prefrontal cortex rewards. Finally, we found was decreased dorsomedial independent sensitivity. These findings demonstrate nuanced use, even among those without disorder, suggest altered reward-related engagement cortico-VS responses as potential predictors developing disordered behavior.

Язык: Английский

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Comparisons of mental health symptoms, treatment access, and self-harm behaviors in rural adolescents before and during the COVID-19 pandemic

European Child & Adolescent Psychiatry, Год журнала: 2022, Номер 32(6), С. 1051 - 1060

Опубликована: Июль 11, 2022

Язык: Английский

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Gaming disorder and the COVID-19 pandemic: Treatment demand and service delivery challenges

Journal of Behavioral Addictions, Год журнала: 2022, Номер 11(2), С. 243 - 248

Опубликована: Апрель 12, 2022

Abstract Gaming activities have conferred numerous benefits during the COVID-19 pandemic. However, some individuals may be at greater risk of problem gaming due to disruption adaptive routines, increased anxiety and/or depression, and social isolation. This paper presents a summary 2019–2021 service data from specialist addiction centers in Germany, Switzerland, Japan, United Kingdom. Treatment demand for disorder has exceeded capacity pandemic, with significant access issues. These highlight need adaptability services resources funding respond effectively future public health crises.

Язык: Английский

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The Evolution of Telepsychiatry for Substance Use Disorders During COVID-19: a Narrative Review

Current Addiction Reports, Год журнала: 2023, Номер 10(2), С. 187 - 197

Опубликована: Апрель 25, 2023

Язык: Английский

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From Reward to Anhedonia-Dopamine Function in the Global Mental Health Context

Biomedicines, Год журнала: 2023, Номер 11(9), С. 2469 - 2469

Опубликована: Сен. 6, 2023

When “hijacked” by compulsive behaviors that affect the reward and stress centers of brain, functional changes in dopamine circuitry occur as consequence pathological brain adaptation. As a correlate mental health, has central role behavioral regulation from healthy reward-seeking to adaptation response adversity. This narrative review offers spotlight view transition function, under control dopamine, progressive deregulation this function interactions with other circuits, producing what may be called an anti-reward state. How such is linked specific health-relevant then explained pandemic-related adversities stresses they engendered. The long lockdown periods where people social isolation had rely on drink, food, digital rewards via internet seen major triggers motivation behavior worldwide. dopamine-mediated discussed. It argued that, when pushed fate circumstance into physiological state anti-reward, human health affected, depending individual vulnerabilities. A unified conceptual account places at centre current global context proposed.

Язык: Английский

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The Effects of a Collegiate Recovery Community Psychotherapy Program Incorporating Equine Interaction during the COVID-19 Pandemic on Young Adults with Substance Abuse Disorder

COVID, Год журнала: 2024, Номер 4(2), С. 151 - 169

Опубликована: Янв. 25, 2024

While psychotherapy incorporating equine interaction (PIE) has proven to be a viable therapeutic intervention, it is not common mental health service found on college campuses. Nevertheless, with the rise of challenges campuses after COVID-19 pandemic, need for effective solutions warranted. Therefore, objective this study was determine effect collegiate recovery community (CRC) PIE program substance abuse disorder (SUD) compared that traditional cognitive behavioral therapy (CBT) and whether physiological synchronization occurs between human horse during process. College-aged adults were recruited pandemic two types short-term SUD interventions, CRC-PIE CBT. Both groups completed self-reporting survey assessing emotional safety. Vital signs measurements participants within collected prior first last sessions. Results concluded although safety did improve significantly by session (p = 0.85), scores different types, lower post-therapy 0.04). As measures participants, respiratory rates (Human: p 0.01; Horse: 0.01) pain rating 0.03; decreased strong positive correlation (R 0.73, R2 0.53) associated vital observed humans horses. This human–horse intervention suggests may tool campus CRC programs development alliances

Язык: Английский

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Impulsivity and aggression as risk factors for internet gaming disorder among university students

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Фев. 14, 2024

Abstract Internet gaming addiction is a global problem, especially among young individuals. Exhibiting characteristics similar to other addictions, Gaming Disorder (IGD) linked adverse mental health outcomes. Identified as risk factors for dependence behaviors, the association of impulsivity and aggression with IGD relatively under-researched in student population. The present sample 350 university students (M age = 21.30 years, SD 4.96 years) from Najran Saudi Arabia completed an online questionnaire that included Scale–Short-Form (IGDS9-SF), Buss–Perry Aggression Questionnaire-Short Form, Barratt Impulsiveness Scale (BIS-15). Results indicated were positively associated severity both personality traits explained 34.6% variance scores. Further bivariate analyses suggested individuals spending 7 or more hours on internet likely exhibit high aggression, had higher IGD. These results suggest these may be vulnerable developing gaming. findings need confirmed future robust studies; however, this exploratory study provides insights potential programs prevent

Язык: Английский

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