Alcohol Use and Its Related Psychosocial Effects during the Prolonged COVID-19 Pandemic in Japan: A Cross-Sectional Survey DOI Open Access
Nagisa Sugaya, Tetsuya Yamamoto, Naho Suzuki

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(24), P. 13318 - 13318

Published: Dec. 17, 2021

We conducted a large-scale survey in the Japanese population, about one year after initial declaration of state emergency, to investigate alcohol use under prolonged coronavirus disease 2019 (COVID-19) pandemic and its related psychosocial demographic characteristics. The was online between 15 20 June 2021. A total 11,427 participants were included analysis (48.5% female, 48.82 ± 13.30 years, range = 20-90 years). Compared with females, males more prevalent hazardous user potential alcoholism group less no alcohol-related problem group. However, prevalence among our study higher than that previously reported. This trend particularly pronounced women. presence deteriorated psychological status, depression anxiety, various difficulties their daily lives due COVID-19 pandemic. In future, intervention methods systems should be developed provide optimal assistance people problems who are vulnerable during pandemic, while conducting further long-term follow-up studies.

Language: Английский

Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being DOI Open Access
Evgenia Gkintoni, Stephanos P. Vassilopoulos, Γεώργιος Νικολάου

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(5), P. 1703 - 1703

Published: March 3, 2025

Background/Objectives: This systematic review outlines the neurocognitive outcomes and mechanisms of mindfulness-based cognitive therapy (MBCT) that influence subjective well-being. MBCT is a clinical intervention integrates with mindfulness practices to prevent depression relapses improve mental health. Methods: The focuses on effects brain structure changes, processes, emotional regulation, which are related improvements in A total 87 studies were included assess effectiveness MBCT. Results: Evidence from highlights reducing symptoms depression, anxiety, stress. was also shown enhance functions regulation across diverse populations. These findings point potential for induce neuroplastic changes widen applicability treatment variety disorders, calling further research into long-term benefits underlying neurobiological mechanisms. Conclusions: emphasizes bring about its study underlines need incorporate multidisciplinary measures by integrating psychology neuroscience comprehend comprehensively

Language: Английский

Citations

2
The Opioid Epidemic: a Crisis Disproportionately Impacting Black Americans and Urban Communities DOI Open Access

Marjorie C. Gondré–Lewis,

Tomilowo Abijo,

Timothy A. Gondré-Lewis

et al.

Journal of Racial and Ethnic Health Disparities, Journal Year: 2022, Volume and Issue: 10(4), P. 2039 - 2053

Published: Sept. 6, 2022

Language: Английский

Citations

52
Delivery of biologics: Topical administration DOI Creative Commons
Rachel J. Kulchar, Rahul Singh, Suwan Ding

et al.

Biomaterials, Journal Year: 2023, Volume and Issue: 302, P. 122312 - 122312

Published: Sept. 4, 2023

Biologics are unaffordable to a large majority of the global population because prohibitively expensive fermentation systems, purification and requirement for cold chain storage transportation. Limitations current production delivery systems biologics were evident during recent pandemic when <2.5% vaccines produced available low-income countries ∼19 million doses discarded in Africa due lack cold-chain infrastructure. Among FDA-approved since 2015, >90% delivered using invasive methods. While oral or topical drugs highly preferred by patients their affordability convenience, only two have been approved FDA 2015. A newly launched biologic costs ∼3% average cost injectable simplified regulatory approval process elimination fermentation, purification, storage/transportation. In addition, developing new product (∼$2.5 billion) has dramatically reduced through delivery. Topical unique advantage targeted high concentration protein drugs, without getting diluted circulating blood. However, very few FDA. Therefore, this review highlights advances proteins at early advanced stages human clinical trials chewing gums, patches sprays, nucleic acid directly, combination with, nanoparticles offers future directions.

Language: Английский

Citations

21
Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults DOI Creative Commons

James Β. Wyngaarden,

Camille Johnston, Daniel Sazhin

et al.

Social Cognitive and Affective Neuroscience, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 1, 2024

Abstract Aberrant levels of reward sensitivity have been linked to substance use disorder and are characterized by alterations in processing the ventral striatum (VS). Less is known about how subclinical relate striatal function during social rewards (e.g. positive peer feedback). Testing this relation critical for predicting risk development disorder. In pre-registered study, participants (N = 44) underwent fMRI while completing well-matched tasks that assess neural response monetary domains. Contrary our hypotheses, aberrant blunted relationship between activation receipt rewards, regardless domain. Moreover, exploratory whole-brain analyses showed unique relations temporoparietal junction. Psychophysiological interactions demonstrated associated with increased connectivity VS ventromedial prefrontal cortex rewards. Finally, we found was decreased dorsomedial independent sensitivity. These findings demonstrate nuanced use, even among those without disorder, suggest altered reward-related engagement cortico-VS responses as potential predictors developing disordered behavior.

Language: Английский

Citations

6
Comparisons of mental health symptoms, treatment access, and self-harm behaviors in rural adolescents before and during the COVID-19 pandemic DOI Open Access
Amy M. Brausch, Meredith B. Whitfield, Rebekah Clapham

et al.

European Child & Adolescent Psychiatry, Journal Year: 2022, Volume and Issue: 32(6), P. 1051 - 1060

Published: July 11, 2022

Language: Английский

Citations

27
Gaming disorder and the COVID-19 pandemic: Treatment demand and service delivery challenges DOI Creative Commons
Daniel L. King, Sophia Achab, Susumu Higuchi

et al.

Journal of Behavioral Addictions, Journal Year: 2022, Volume and Issue: 11(2), P. 243 - 248

Published: April 12, 2022

Abstract Gaming activities have conferred numerous benefits during the COVID-19 pandemic. However, some individuals may be at greater risk of problem gaming due to disruption adaptive routines, increased anxiety and/or depression, and social isolation. This paper presents a summary 2019–2021 service data from specialist addiction centers in Germany, Switzerland, Japan, United Kingdom. Treatment demand for disorder has exceeded capacity pandemic, with significant access issues. These highlight need adaptability services resources funding respond effectively future public health crises.

Language: Английский

Citations

23
The Evolution of Telepsychiatry for Substance Use Disorders During COVID-19: a Narrative Review DOI Open Access
Noam Fast, Robin van Kessel, Keith Humphreys

et al.

Current Addiction Reports, Journal Year: 2023, Volume and Issue: 10(2), P. 187 - 197

Published: April 25, 2023

Language: Английский

Citations

15
From Reward to Anhedonia-Dopamine Function in the Global Mental Health Context DOI Creative Commons
Birgitta Dresp

Biomedicines, Journal Year: 2023, Volume and Issue: 11(9), P. 2469 - 2469

Published: Sept. 6, 2023

When “hijacked” by compulsive behaviors that affect the reward and stress centers of brain, functional changes in dopamine circuitry occur as consequence pathological brain adaptation. As a correlate mental health, has central role behavioral regulation from healthy reward-seeking to adaptation response adversity. This narrative review offers spotlight view transition function, under control dopamine, progressive deregulation this function interactions with other circuits, producing what may be called an anti-reward state. How such is linked specific health-relevant then explained pandemic-related adversities stresses they engendered. The long lockdown periods where people social isolation had rely on drink, food, digital rewards via internet seen major triggers motivation behavior worldwide. dopamine-mediated discussed. It argued that, when pushed fate circumstance into physiological state anti-reward, human health affected, depending individual vulnerabilities. A unified conceptual account places at centre current global context proposed.

Language: Английский

Citations

13
The Effects of a Collegiate Recovery Community Psychotherapy Program Incorporating Equine Interaction during the COVID-19 Pandemic on Young Adults with Substance Abuse Disorder DOI Creative Commons

Katie Holtcamp,

Molly C. Nicodemus,

Tommy M. Phillips

et al.

COVID, Journal Year: 2024, Volume and Issue: 4(2), P. 151 - 169

Published: Jan. 25, 2024

While psychotherapy incorporating equine interaction (PIE) has proven to be a viable therapeutic intervention, it is not common mental health service found on college campuses. Nevertheless, with the rise of challenges campuses after COVID-19 pandemic, need for effective solutions warranted. Therefore, objective this study was determine effect collegiate recovery community (CRC) PIE program substance abuse disorder (SUD) compared that traditional cognitive behavioral therapy (CBT) and whether physiological synchronization occurs between human horse during process. College-aged adults were recruited pandemic two types short-term SUD interventions, CRC-PIE CBT. Both groups completed self-reporting survey assessing emotional safety. Vital signs measurements participants within collected prior first last sessions. Results concluded although safety did improve significantly by session (p = 0.85), scores different types, lower post-therapy 0.04). As measures participants, respiratory rates (Human: p 0.01; Horse: 0.01) pain rating 0.03; decreased strong positive correlation (R 0.73, R2 0.53) associated vital observed humans horses. This human–horse intervention suggests may tool campus CRC programs development alliances

Language: Английский

Citations

5
Impulsivity and aggression as risk factors for internet gaming disorder among university students DOI Creative Commons
Mohammad Ahmed Hammad, Hend Faye AL-shahrani

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 14, 2024

Abstract Internet gaming addiction is a global problem, especially among young individuals. Exhibiting characteristics similar to other addictions, Gaming Disorder (IGD) linked adverse mental health outcomes. Identified as risk factors for dependence behaviors, the association of impulsivity and aggression with IGD relatively under-researched in student population. The present sample 350 university students (M age = 21.30 years, SD 4.96 years) from Najran Saudi Arabia completed an online questionnaire that included Scale–Short-Form (IGDS9-SF), Buss–Perry Aggression Questionnaire-Short Form, Barratt Impulsiveness Scale (BIS-15). Results indicated were positively associated severity both personality traits explained 34.6% variance scores. Further bivariate analyses suggested individuals spending 7 or more hours on internet likely exhibit high aggression, had higher IGD. These results suggest these may be vulnerable developing gaming. findings need confirmed future robust studies; however, this exploratory study provides insights potential programs prevent

Language: Английский

Citations

5