High level of psychological stress in COVID-19 recovered individuals: role of copeptin as a potential biomarker DOI Creative Commons

Phibakordor Lyngdoh Nonglait,

Sri Venkata Madhu,

Nishant Raizada

и другие.

Frontiers in Psychology, Год журнала: 2023, Номер 14

Опубликована: Дек. 13, 2023

Background Study aimed to assess stress in COVID-19 recovered individuals using a validated questionnaire PSS-10 score and biomarkers – salivary cortisol serum copeptin. Methods A total of 83 subjects which 54 (66.3%) who were hospitalized recruited 8–20 weeks following recovery from COVID-19. Stress was assessed by stress-scale after mean duration 14.5 recovery. Sixty-eight (81.9%) had new or persistent symptoms Subjects divided into two groups on the basis PSS score; mild (PSS:0–13) moderate severe (PSS:>14) levels (serum copeptin, DHEAS cortisol) compared groups. Results Forty-four (53%) 39 (47%) stress. with post COVID significantly higher as asymptomatic [15 vs. 9; p = 0.003]. Serum copeptin among those [0.41 0.67 ng/mL; 0.031]. median [1.03 1.44 nmol/L; 0.448]. Conclusion Our study demonstrated over half some level nearly all even 3 months. found be useful biomarker objectively measure these subjects.

Язык: Английский

Neurocognitive Changes in Patients with Post-COVID Depression DOI Open Access
Marina Khodanovich, Anna Naumova, Daria Kamaeva

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(5), С. 1442 - 1442

Опубликована: Март 1, 2024

Background: Depression and cognitive impairment are recognized complications of COVID-19. This study aimed to assess performance in clinically diagnosed post-COVID depression (PCD, n = 25) patients using neuropsychological testing. Methods: The involved 71 with matched control groups: recovered COVID-19 individuals without (n 18) prior history 19). A group was identified based on psychiatric diagnosis, a comparison (noPCD, 46) included participants neurological complications, excluding clinical depression. Results: PCD showed gender-dependent significant the MoCA, Word Memory Test (WMT), Stroop task (SCWT), Trail Making (TMT) compared controls noPCD patients. Men worse performances SCWT, MoCA attention score, WMT (immediate delayed word recall), while women decline total an increased processing time less errors TMT, immediate recall. No differences between groups Sniffin's stick test were found. Conclusions: COVID-related direct (post-COVID symptoms) depression-mediated (depression itself, male sex, severity COVID-19) predictors memory information speed identified. Our findings may help personalize treatment depression, taking patient's gender previous disease into account.

Язык: Английский

Процитировано

2

Evaluation of Psychosomatic, Respiratory, and Neurocognitive Health in COVID-19 Survivors 12 Months after ICU Discharge DOI Open Access
Nicolas Germann,

Daria Amozova,

Kristina Göhl-Freyn

и другие.

Опубликована: Июль 5, 2024

Patients who survived critical COVID-19 frequently reported post-acute sequelae of (PASC) such as psychosomatic and neurocognitive health problems. The goal this study was to identify clinical risk factors other predictors for long-term consequences in severely ill patients. Adult intensive care unit (ICU) survivors from August 2020 May 2021 were enrolled. A broad range clinical, laboratory chest computed tomography (CT) data collected during ICU stay. association between psychosomatic, respiratory assessments 12 months after discharge analyzed using univariate regression analysis. In 17 patients (mean age 58.9 ± 11.4 years), markers (CRP, lymphocytes, hemoglobin), severity (SOFA, SAPS II, need mechanical ventilation), complications (ARDS), lung CT (ground-glass opacity) promising depressive anxiety symptoms, fatigue, sleep Recovery depression correlated with lower levels inflammation high hemoglobin levels. ARDS, ventilation worse SOFA II scores further symptoms. Our identified novel associations pulmonary ground-glass opacity being positively associated depression, anxiety, insomnia

Язык: Английский

Процитировано

1

Characterization of COVID-19 Hospitalized Patients in Three United States Electronic Health Record Databases DOI Creative Commons
Patrick Saunders‐Hastings, Cindy Ke Zhou, Shayan Hobbi

и другие.

Pathogens, Год журнала: 2023, Номер 12(3), С. 390 - 390

Опубликована: Март 1, 2023

COVID-19 infections have contributed to substantial increases in hospitalizations. This study describes demographics, baseline clinical characteristics and treatments, outcomes among U.S. patients admitted hospitals with during the prevaccine phase of pandemic. A total 20,446 hospitalized a positive nucleic acid amplification test were identified from three large electronic health record databases 5 February-30 November 2020 (Academic Health System: n = 4504; Explorys; 7492; OneFlorida: 8450). Over 90% ≥30 years age, an even distribution between sexes. At least one comorbidity was recorded 84.6-96.1% patients; cardiovascular respiratory conditions (28.8-50.3%) diabetes (25.6-44.4%) most common. Anticoagulants frequently reported medications on or up 28 days after admission (44.5-81.7%). Remdesivir administered 14.1-24.6% increased over time. Patients exhibited higher severity 14 following than prior admission. The length in-patient hospital stay ranged median 4 6 days, 85% discharged alive. These results promote understanding hospital-resource utilization associated

Язык: Английский

Процитировано

2

The impact of family function on post-traumatic reactions of Chinese adolescents infected with COVID-19: a latent profile study DOI Creative Commons

Mingtu Xu,

Runhui Tian,

Cong Fu

и другие.

Frontiers in Public Health, Год журнала: 2023, Номер 11

Опубликована: Май 4, 2023

Background Since the end of 2019, Corona Virus Disease also known as COVID-19, has broken out in various countries. However, change China's COVID-19 prevention and control policy sharp increase number infected people are making teenagers have post-traumatic reactions. Negative reactions include: stress disorder (PTSD), depression, anxiety. Positive reaction mainly refers to growth (PTG). The purpose this study is explore reaction, which PTSD, anxiety co-occurrence pattern after trauma further influence family function on different categories Post-traumatic Reactions. Methods Latent profile analysis (LPA) was used anxiety, PTG. Multiple logistics regression analyze response. Results There were three adolescents with namely: class, struggling pain class. Multivariate Logistic showed that class affected by problem solving behavior function, while solving, roles, control, general functioning. logistic roles. Conclusions findings provide evidence for identification high-risk individuals provision effective interventions clinical practice, well functioning PTSD among COVID-19.

Язык: Английский

Процитировано

2

Psychological Health in Intensive Care Unit Health Care Workers after the COVID-19 Pandemic DOI Open Access
Valeria Carola, Cristina Vincenzo,

Chiara Morale

и другие.

Healthcare, Год журнала: 2022, Номер 10(11), С. 2201 - 2201

Опубликована: Ноя. 2, 2022

Background: Although the COVID-19 pandemic had an impact on general population, health care workers (HCWs) constituted one of groups that were most adversely affected by associated risks, owing to significant consequences their mental health. This study examined these psychological effects HCWs who cared for patients admitted intensive unit in Italian hospital. Methods: Subjects administered several self-reported questionnaires: Kessler 10 Psychological Distress Scale (K10), Perceived Stress Scale-10 (PSS), Impact Event Revised (IES-R), and Post-traumatic Growth Inventory (PTGI), as well two open-ended questions oriented toward understanding positive negative emotional experience differentiating between phases emergency. Results: Overall, 45% showed medium-to-high anxiety/depressive symptoms, whereas 60% presented with levels perceived stress. In addition, 37% subjects developed symptoms PTSD 50% post-traumatic growth “appreciation life” “new possibilities” dimensions. With regard questions, three themes identified: quality workplace relationships, sense emotional-relational competence, clinical-technical competence. macrocategories responses identified answers: block. Conclusions: The are involved front line was significantly impacted this experience, showing high stress anxiety depressive more than 1 year after emergency began. A qualitative analysis staff experiences can be a useful guide structuring interventions prevention.

Язык: Английский

Процитировано

4

The Psychological Impact of COVID-19 Admission on Families: Results from a Nationwide Sample in Greece DOI Creative Commons
Despoina Gkentzi,

Konstantinos Mhliordos,

Ageliki Karatza

и другие.

Children, Год журнала: 2022, Номер 9(12), С. 1933 - 1933

Опубликована: Дек. 9, 2022

The aim of the present study was to assess psychological impact hospitalization during COVID-19 pandemic on parents and their offspring. We performed a nationwide cross-sectional in Greece based an Internet questionnaire survey. A convenience sample whose offspring had been hospitalized due (including multisystem inflammatory syndrome children, MIS-C), diagnosed with but not hospitalized, for another reason were enrolled. Parental stress assessed using Perceived Stress Scale (PSS) Revised Impact Event (IES-R) tools, childhood mental wellbeing Children’s 13 (CRIES-13) scale. Out 214 received responses, levels significantly higher children admitted or MIS-C versus those other reasons (p < 0.001, PSS/IES-R). correlated. In multivariable linear regression analysis, children’s because MIS-C, younger parental age, existence comorbidities, family member’s independent factors stress. light above, stricter hospital admission criteria could be implemented, support eventually families may beneficial.

Язык: Английский

Процитировано

3

Exploring the Psychosocial Impacts on COVID-19 Survivors: A Qualitative Study of Life after COVID-19 Diagnosis and Quarantine in South Korea DOI
Min Ah Kim, Jaehee Yi, Jimin Sung

и другие.

Journal of Social Service Research, Год журнала: 2024, Номер 50(3), С. 325 - 341

Опубликована: Янв. 9, 2024

COVID-19 infection and subsequent quarantine experiences during the pandemic may have profoundly affected many aspects of life among survivors. However, limited research has explored changes these survivors experienced once they returned to their daily lives. This study aimed explore survivors' psychosocial impacts lives following social initial phase in South Korea. Semistructured telephone interviews were conducted June 2021, involving 15 All participants contracted between February 2020 April 2021 used a qualitative methodology from phenomelogical perspectives understand participants' shared lived experiences. Thematic analysis identified four overarching themes 12 subthemes Korean survivors: (a) self-concept transformation; (b) changed relationship dynamics; (c) perspective shifts; (d) health awareness evolution. Recognizing by can inform development targeted peer support services person-centered education. Focusing on empowerment, initiatives promote personal growth, facilitate positive changes, alleviate traumatic for future diverse infectious diseases. Future could investigate long-term impact individuals' mechanisms underlying effects.

Язык: Английский

Процитировано

0

Evaluation of Psychosomatic, Respiratory, and Neurocognitive Health in COVID-19 Survivors 12 Months after ICU Discharge DOI Creative Commons
Nicolas Germann,

Daria Amozova,

Kristina Göhl-Freyn

и другие.

COVID, Год журнала: 2024, Номер 4(8), С. 1172 - 1185

Опубликована: Июль 30, 2024

Patients who survive critical COVID-19 frequently report post-acute sequelae of (PASC) such as psychosomatic and neurocognitive health problems. The goal this study was to identify clinical risk factors other predictors for long-term consequences in severely ill patients. Adult intensive care unit (ICU) survivors from August 2020 May 2021 were enrolled. A broad range clinical, laboratory chest computed tomography (CT) data collected during their ICU stays. association between psychosomatic, respiratory, assessments 12 months after discharge analyzed using univariate regression analysis. In 17 patients (mean age 58.9 ± 11.4 years), markers (CRP, lymphocytes, hemoglobin), severity (SOFA, SAPS II, need mechanical ventilation), complications (ARDS), lung CT (ground-glass opacity) promising depressive anxiety symptoms, fatigue, sleep Recovery depression, correlated with lower levels inflammation high hemoglobin levels. ARDS, ventilation, worse SOFA II scores further symptoms. Our identified novel associations pulmonary ground-glass opacity being positively associated anxiety, insomnia

Язык: Английский

Процитировано

0

Evaluation of the mental health of COVID-19 patients discharged from the intensive care unit DOI

Elif Sarac

World Journal of Clinical Cases, Год журнала: 2024, Номер 12(33), С. 6587 - 6590

Опубликована: Сен. 27, 2024

In this editorial, I address the mental health status of patients who have been discharged from intensive care units (ICUs) after battling coronavirus disease 2019 (COVID-19). An ICU admission is generally a stressful experience, and for severe COVID-19 survivors prolonged treatment in can lead to significant psychological consequences. These individuals may experience psychiatric distress, including symptoms such as insomnia, anxiety, depression, even post-traumatic issues. Research indicates that during first 6 months 1 year following an stay, nearly one-third exhibit similar those depression stress disorder. Several factors contributed development depressive anxious pandemic, particularly underwent stay. The environment itself inherently stressful, filled with constant noise various medical devices. Studies provided strong evidence need ventilation support loss freedom movement are key problems among had treated ICU.

Язык: Английский

Процитировано

0

High level of psychological stress in COVID-19 recovered individuals: role of copeptin as a potential biomarker DOI Creative Commons

Phibakordor Lyngdoh Nonglait,

Sri Venkata Madhu,

Nishant Raizada

и другие.

Frontiers in Psychology, Год журнала: 2023, Номер 14

Опубликована: Дек. 13, 2023

Background Study aimed to assess stress in COVID-19 recovered individuals using a validated questionnaire PSS-10 score and biomarkers – salivary cortisol serum copeptin. Methods A total of 83 subjects which 54 (66.3%) who were hospitalized recruited 8–20 weeks following recovery from COVID-19. Stress was assessed by stress-scale after mean duration 14.5 recovery. Sixty-eight (81.9%) had new or persistent symptoms Subjects divided into two groups on the basis PSS score; mild (PSS:0–13) moderate severe (PSS:&gt;14) levels (serum copeptin, DHEAS cortisol) compared groups. Results Forty-four (53%) 39 (47%) stress. with post COVID significantly higher as asymptomatic [15 vs. 9; p = 0.003]. Serum copeptin among those [0.41 0.67 ng/mL; 0.031]. median [1.03 1.44 nmol/L; 0.448]. Conclusion Our study demonstrated over half some level nearly all even 3 months. found be useful biomarker objectively measure these subjects.

Язык: Английский

Процитировано

0