Clinical and psychosocial context of HIV perinatally infected young mothers in Harare, Zimbabwe: A longitudinal mixed-methods study
PLoS ONE,
Год журнала:
2025,
Номер
20(1), С. e0315299 - e0315299
Опубликована: Янв. 10, 2025
Background
The
lives
of
adolescents
and
young
people
living
with
HIV
(LHIV)
are
dominated
by
complex
psychological
social
stressors.
These
may
be
more
pronounced
among
those
perinatally
infected.
This
longitudinal
mixed-methods
study
describes
the
clinical
psychosocial
challenges
faced
infected
mothers
in
Harare,
Zimbabwe
to
inform
tailored
support.
Methods
were
recruited
2013
followed
up
2019.
In
2013,
they
completed
a
structured
interview,
examination,
screening
had
viral
load
drug
resistance
testing.
A
subset
in-depth
interviews
(n
=
10).
2019,
re-interviewed
Data
analyzed
using
STATA
15.0.
thematic
analysis.
Results
Nineteen
aged
17–24
years
2013.
Eleven
(57.9%)
successfully
recontacted
2019;
3
died,
2
relocated
untraceable.
all
19
taking
antiretroviral
therapy
(median
duration
8
years,
range
2–11
years)
median
CD4
count
was
524
(IQR
272).
eight
(42.1%)
virological
failure
(≥1000
copies/ml)
(3
whom
subsequently
died)
7
(36.8%)
evidence
resistance.
proportion
2/11
(18.1%).
Six
11
(54.5%)
switched
second
line
therapy.
64.3%
at
risk
common
mental
disorder
this
higher
follow-up
(72.7%).
Qualitative
data
highlighted
three
pertinent
themes:
status
disclosure,
adherence
experiences
and,
emotional
Conclusions
Findings
from
underscore
significant
clinical,
mothers.
high
rates
failure,
resistant
mutations,
health
issues
mortality
observed
population
indicate
need
for
comprehensive
support
services
assist
these
Язык: Английский
Mental health and other clinical and social characteristics of young mothers living with HIV in Zimbabwe: a mixed-methods study
AIDS Care,
Год журнала:
2025,
Номер
unknown, С. 1 - 11
Опубликована: Март 7, 2025
Young
women
living
with
HIV
(YWLHIV)
experience
numerous
stressors
including
treatment
management
and
poor
parent
modelling.
We
investigated
YWLHIV's
mental
health
other
clinical
social
characteristics
to
inform
tailored
support.
YWLHIV
(15-24
years
old)
participating
in
a
peer-support
model
for
young
mothers
(Young
Mentor
Mum
intervention)
completed
self-administered
interview
had
psychological
assessments
March
April
2019.
A
subset
participated
in-depth
interviews
their
partners
interviewed.
analysed
quantitative
qualitative
data
using
STATA
15
thematic
analysis,
respectively.
enrolled
177
YWLHIV.
found
high
rates
of
maternal
viral
suppression
(86.9%
load
<1000
copies/ml).
Over
half
were
at
risk
common
disorder
(CMD),
scoring
above
the
cut-off
point
(SSQ
≥8,
50.3%)
depression
(EPDS
≥12,
55.9%).
CMD
was
higher
among
who
reported
intimate
partner
violence
past
year
(64.1%
vs
39.4%;
adjusted
OR
2.48
(1.12,
5.48)
1-2
times
2.41
(0.99-5.85)
frequency;
p
=
.03).
status
disclosure
limited;
only
44.1%
disclosed
partners.
confront
challenges
which
affect
that
children.
Youth-focused
interventions
coupled
couples
counselling
prevention
need
be
scaled
up.
Язык: Английский
Dynamic Network Analysis of Mental Health Symptoms Among Persons Living With HIV
Journal of Advanced Nursing,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 30, 2025
ABSTRACT
Aim
This
study
aims
to
develop
dynamic
networks
and
examine
the
longitudinal
relationships
of
mental
health
symptoms
among
persons
living
with
HIV
(PLWH).
Design
A
study.
Methods
We
collected
data
between
October
2022
December
using
Wenjuanxing
(Questionnaire
Star),
an
online
survey
platform.
The
tracked
weekly
across
10
sessions,
involving
123
PLWH
in
Beijing,
China.
total
40
six
dimensions
(somatization
symptoms,
negative
affect,
cognitive
processes,
function,
interpersonal
communication
social
adaptation)
were
included
symptom
network,
which
consists
temporal,
contemporaneous
between‐person
networks.
Results
In
temporal
‘feeling
inferior
others’
had
largest
in‐strength
value,
whereas
‘suicidal
ideation’
exhibited
out‐strength
value.
showed
highest
bridge
strength,
indicating
it
most
connections
other
symptoms.
Conclusions
found
that
number
predictors,
up
seven
potentially
triggering
this
particular
symptom.
Additionally,
emerged
as
a
powerful
predictor,
influencing
greatest
five
dimensions.
Impact
Our
enhances
understanding
sequential
development
consequences
PLWH,
may
provide
important
basis
for
designing
precise
management
interventions.
Reporting
Method
was
reported
according
STROBE
checklist.
Patient
or
Public
Contribution
No
patient
public
contribution.
Язык: Английский
Leaving no one behind? Addressing inequitable HIV outcomes by attending to diversity: A qualitative study exploring the needs of LGBTQI+ young people living with HIV in Zimbabwe
PLOS Global Public Health,
Год журнала:
2024,
Номер
4(1), С. e0002442 - e0002442
Опубликована: Янв. 25, 2024
Leaving
nobody
behind
in
the
fight
to
end
HIV
epidemic
as
a
public
health
threat
depends
on
addressing
inequities
optimal
outcomes.
Consistently
overlooked
research,
policy
and
programming
are
young
lesbian,
gay,
bisexual,
transgender,
queer/questioning
intersex
(LGBTQI+)
people
who
living
with
HIV.
This
study
engaged
LGBTQI+
Zimbabwe
better
understand
their
experiences
of
support
they
need.
Between
September
2022
February
2023,
we
conducted
qualitative
research
14
(18–24
years),
(two
focus
group
discussions
in-depth
interviews
5/14).
All
participants
were
accessing
at
Zvandiri
(‘As
I
Am’),
well-established
community-based
program.
We
thematic
analysis
key
findings
informed
collaborative
development
internal
activities
further
enhance
inclusivity
within
Zvandiri’s
programs.
There
was
consensus
among
that
being
leads
“double
stigma
double
trouble”
,
involving
physical
verbal
harassment,
social
exclusion
family
rejection.
Participants
concealed
identity
status
most
situations,
many
withheld
spaces,
including
community-led
services.
negatively
impacted
psychosocial
well-being
connectedness.
described
positive
Zvandiri.
Interacting
others
destigmatising
environment
promoted
self-acceptance.
However,
reflecting
prevailing
experiences,
cautious
about
revealing
sexuality
and/or
gender
outside
group.
Ensuring
equitable
access
care,
mental
support,
relies
understanding
challenges
experienced
by
those
marginalised.
Critically
important
is
impact
intersectional
peoples’
lives,
Community-based
programs
well-positioned
advance
this
group’s
rights.
Язык: Английский
A qualitative analysis of self-management needs of adolescents and young adults living with perinatally acquired HIV in rural, southwestern Uganda
PLOS Global Public Health,
Год журнала:
2024,
Номер
4(3), С. e0003037 - e0003037
Опубликована: Март 18, 2024
The
number
of
adolescents
living
with
HIV
remains
high
in
sub-Saharan
Africa
poorer
treatment
outcomes
among
and
young
adults
compared
to
individuals
other
age
groups.
For
perinatally
acquired
(AYLPHIV),
the
transition
from
pediatric
adult
care
is
a
particularly
high-risk
period.
We
conducted
qualitative
study
understand
self-management
needs
AYLPHIV
rural,
southwestern
Uganda
as
they
prepare
order
inform
relevant
interventions
that
can
enable
acquire
necessary
skills
manage
their
illness
into
adulthood.
60
in-depth
interviews
(n
=
30),
caregivers
20)
health
providers
10)
clinic
at
Mbarara
Regional
Referral
Hospital.
used
an
interview
guide
focused
on
perceptions
about
care,
challenges
transitioning,
navigating
for
(from
perspectives
AYLPHIV,
caregivers,
providers).
thematic
analysis
identify
themes
related
AYLPHIV’s
skills.
identified
several
we
grouped
under
two
major
themes;
social
support
empowerment
assume
responsibility
own
navigate
independently.
sub-themes
were
information
support,
instrumental
emotional
sub
while
included
self-advocacy
skills,
interpersonal
self-care
disclosure
Taken
together,
these
findings
indicate
need
be
supported
empowered
maximize
chances
successfully
transitioning
care.
Support
comes
peers
caregivers.
require
knowledge
status
different
including:
responsibilities
independent
Язык: Английский
Stigma and fear of getting sick in the care of people living with HIV: an exploratory systematic review
Infezioni in Medicina,
Год журнала:
2024,
Номер
32(2)
Опубликована: Май 30, 2024
The
aim
of
the
present
study
was
to
explore
stigma
and
fear
getting
sick
in
health
professionals
who
treat
people
living
with
HIV.
An
exploratory
systematic
review
conducted.
search
limited
presence
on
part
healthcare
workers
HIV,
documented
by
or
patients
themselves.
No
language
restriction
made
reviews,
comments
communications
were
excluded.
sources
information
Scopus,
PubMed/MEDLINE,
Science
Direct,
CENTRAL
Registry,
from
last
5
years.
quality
evidence
assessed
an
adapted
tool
synthesis
results
carried
out
using
a
narrative
approach.
Twenty-three
articles
included,
which
related
structural
stigma,
sick.
Among
findings,
data
stood
such
as
that
more
than
50%
reported
having
experienced
discrimination
due
HIV
even
accumulated
for
other
additional
causes.
Stigma
enacted
settings
suboptimal
adherence
treatment
(OR
1.38;
95%
CI:
1.03-1.84;
p=0.028).
is
barrier
care
generates
psychological,
physical,
social
impact
these
people.
Some
limitations
are
that,
despite
searching
major
databases,
important
manuscripts
may
have
been
left
out.
Additionally,
there
regions
not
represented
this
because
no
those
areas
found.
Язык: Английский
A conceptualization and psychometric evaluation of positive psychological outcome measures used in adolescents and young adults living with HIV: A mixed scoping and systematic review
PLOS Global Public Health,
Год журнала:
2024,
Номер
4(8), С. e0002255 - e0002255
Опубликована: Авг. 12, 2024
Introduction
Sub-Saharan
Africa
bears
the
greatest
burden
of
HIV,
with
comorbid
mental
conditions
highly
prevalent
in
people
living
HIV.
It
is
important
to
evaluate
health
adolescents
and
young
adults
HIV
(AYALHIV)
comprehensively
by
measuring
both
negative
positive
psychological
constructs.
There
has
been
a
proliferation
interest
outcome
measures,
but
evidence
their
psychometric
robustness
fragmented.
This
review
sought
to:
1)
Identify
outcomes
corresponding
measures
used
AYALHIV
sub-Saharan
Africa.
2)
Critically
appraise
psychometrics
identified
measures.
Methods
analysis
Two
reviewers
independently
searched
articles
PubMed,
Scopus,
Africa-Wide
Information,
CINAHL,
Psych
INFO
Google
Scholar.
Searches
were
conducted
from
November
2022
February
2023.
separate
reviewed
retrieved
articles.
We
applied
narrative
synthesis
map
key
The
risk
bias
across
studies
was
evaluated
using
COnsensus-based
Standards
for
selection
Measurement
INstruments
(COSMIN)
checklist.
quality
properties
rated
COSMIN
checklist
qualitatively
synthesized
modified
Grading
Recommendations
Assessment,
Development,
Evaluation
Results
15
constructs:
body
appreciation,
confidence,
coping,
flourishing,
meaningfulness,
personal
control,
outlook,
resilience,
self-management,
self-compassion,
self-concept,
self-efficacy,
self-esteem,
self-worth
transcendence,
that
had
assess
ALHIV.
most
measured
constructs
coping
self-efficacy.
Construct
validity
internal
consistency
frequently
considered,
while
content
structural
assessed
less
often.
Conclusions
Few
performed
complete
validations;
thus,
However,
this
shows
initial
feasibility
low-resource
settings.
Instead
creating
new
researchers
are
recommended
leverage
existing
adapt
them
use
and,
if
appropriate,
strive
maintain
factorial
structure
facilitate
comparisons.
Registration
PROSPERO-
CRD42022325172
.
Язык: Английский
Reported impact of creativity in the Wakakosha (‘You’re Worth It’) internal stigma intervention for young people living with HIV in Harare, Zimbabwe
PLOS Global Public Health,
Год журнала:
2024,
Номер
4(11), С. e0003909 - e0003909
Опубликована: Ноя. 5, 2024
Internal
stigma
(negative
judgements
towards
oneself)
continues
to
be
a
barrier
HIV
treatment,
management
and
care,
has
global
public
health
consequences.
People
living
with
(PLHIV)
who
report
internal
are
less
likely
seek
adhere
treatment
can
experience
increased
depression
lower
quality
of
life.
The
Wakakosha
(‘You’re
Worth
It’)
programme
sought
reduce
among
young
PLHIV
using
inquiry-based
stress
reduction
(IBSR),
cognitive
awareness-based
methodology.
This
sub-study
focused
on
creativity,
exploring
how
it
promotes
PLHIV’s
well-being.
We
analysed
individual
interviews
(n
=
14),
focus
groups
3),
poems
5),
songs
2)
self-compassion
letters
38)
23
activity
journals
from
November
2021
March
2022,
utilising
inductive
thematic
analysis
identify
themes
across
the
data.
Creativity
saturated
intervention
through
modalities
such
as
drawing,
colouring,
body
mapping,
music
letter
writing.
These
engaged
participants
gave
them
space
in
which
shift
their
stigmatising
beliefs,
helped
multiple
ways
including:
facilitating
emotional
regulation,
self-acceptance,
self-compassion,
self-worth
positivity.
also
enhanced
participants’
self-image
allowed
see
own
abilities.
Music
improved
therapeutic
environment
by
helping
focus,
emote,
retain
messages
connect
within
group
setting.
Letters
self/others
let
go
themselves
circumstances
infection.
Tools
drawing
mapping
assisted
recognition
expression.
provided
insight
into
potential
when
integrated
an
IBSR
intervention,
counteracting
stigma.
Ongoing
replication
is
needed
continue
evolve
best
practices
for
interventions.
Future
work
should
use
more
structured
specific
regarding
creative
processes.
Язык: Английский
A Scoping Review on Peer-led Interventions to Improve Youth Mental Health in Low- and Middle-Income Countries
Cambridge Prisms Global Mental Health,
Год журнала:
2024,
Номер
12
Опубликована: Дек. 16, 2024
Abstract
Youth
living
in
low-
and
middle-income
countries
(LMICs)
have
an
increased
vulnerability
to
mental
illnesses,
with
many
lacking
access
adequate
treatment.
There
has
been
a
growing
body
of
interventions
using
task
sharing
trained
peer
leaders
address
this
health
gap.
This
scoping
review
examines
the
characteristics,
effectiveness,
components
delivery
challenges
peer-led
for
youth
aged
10–24
LMICs.
A
key
term
search
strategy
was
employed
across
MEDLINE,
Embase,
Web
Science,
Global
Health
Index
Medicus.
Eligibility
criteria
included
young
people
component
delivered
any
setting
LMIC.
Study
selection
extraction
were
conducted
independently
by
first
second
authors,
discrepancies
resolved
senior
author.
characteristics
summarised
presented
descriptively.
The
identified
5,358
citations,
19
studies
included.
14
quantitative,
four
qualitative
one
mixed
methods
study
reporting
outcomes.
Types
heterogenous
but
fell
within
three
broad
categories:
(1)
education
psychoeducation,
(2)
psychotherapy
counselling
(3)
support.
All
reported
improved
outcomes
as
result
interventions.
Peer-led
are
versatile
terms
both
types
mode
delivery.
Lived
experience,
mutual
respect
reduced
stigma
make
method
highly
unique
effective
way
engage
age
group.
However,
implementing
is
not
without
challenges.
Adequate
training,
supervision,
cultural
appropriateness
support
from
established
institutions
critical
safeguarding
ensuring
sustainability
such
programs.
Our
findings
suggest
that
models
valuable
intervention
policymakers
can
leverage
current
future
efforts
Future
areas
research
should
expand
include
perspectives
other
stakeholders
involved
implementation
interventions,
focusing
on
factors
including
fidelity,
feasibility
acceptability
enhance
insights.
Язык: Английский
“I realized I had a choice”: the forgiveness journey of people living with HIV
AIDS Care,
Год журнала:
2024,
Номер
37(1), С. 62 - 73
Опубликована: Окт. 9, 2024
Forgiveness,
a
process
of
relinquishment
resentment,
hostility,
and
anger
toward
an
offender
or
self,
is
understudied
among
people
living
with
HIV.
This
study
examined
the
experience
forgiving
person
who
allegedly
transmitted
HIV,
In-depth
interviews
were
conducted
14
HIV
aged
25
older,
diagnosed
at
least
three
years
before
study.
Three
main
themes
emerged:
"Anger
poison":
between
forgiveness
unforgiveness;
"I
gave
up
drive
to
suffer":
meaning
forgiveness;
"Forgiving
like
building
building":
phases
unforgiveness.
revealed
cognitive
emotional
processes
forgiveness.
Forgiveness-focused
interventions
for
are
suggested.
Язык: Английский