Insights into the Donkey Hindgut Microbiome Using Metagenome-Assembled Genomes DOI Creative Commons
Xiyan Kou,

Yihong Liu,

Fokun Xiang

и другие.

Animals, Год журнала: 2024, Номер 14(24), С. 3625 - 3625

Опубликована: Дек. 16, 2024

The gut microbiota plays an important role in the digestion, absorption, and metabolism of nutrients, as well immunity, health, behavior donkeys. While reference genomes microbial gene catalogs have been helpful understanding composition donkey, there is still a significant gap sequencing functional aspects donkey genomes. In this study, we analyzed metagenomic data from 26 donkeys’ samples successfully assembled 844 metagenome-assembled (MAGs). Surprisingly, 678 (80.33%) these MAGs appear to belong previously unidentified species. Our analysis further revealed total 292,980 predicted carbohydrate-active enzymes (CAZymes) 257,893 polysaccharide utilization loci (PULs). Interestingly, displayed relatively low similarity matches public databases. We found that higher abundances 36 cecum (such Prevotella, Desulfovibrio, Alistipes, Treponema_D) 9 dorsal colon Limimorpha, Saccharofermentans, Lactobacillus) were associated with diverse array carbohydrate-degrading pathways. Network identified Prevotella Dysosmobacter connectors, while Saccharofermentans Akkermansia shown provincial hubs. This suggests their crucial roles complex carbohydrate degradation hindgut These findings underscore complexity donkeys expand our microbiome. Overall, study provides comprehensive catalog genes, revealing novel offering new insights for future research on

Язык: Английский

Molecular prevalence and associated risk factors of Entamoeba spp. in donkeys in Shanxi Province, North China DOI Creative Commons

Ze-Dong Zhang,

Han-Dan Xiao,

Dongyang Wang

и другие.

Parasites & Vectors, Год журнала: 2025, Номер 18(1)

Опубликована: Фев. 5, 2025

Язык: Английский

Процитировано

1

Advances in Donkey Disease Surveillance and Microbiome Characterization in China DOI Creative Commons
Muhammad Zahoor Khan, Yan Li, Mingxia Zhu

и другие.

Microorganisms, Год журнала: 2025, Номер 13(4), С. 749 - 749

Опубликована: Март 26, 2025

This review article highlights the surveillance of bacterial, viral, and parasitic diseases in donkey populations China. Key findings highlight significant threats from Equine herpesviruses (EHV-8 EHV-1), which cause encephalitis, abortion, respiratory distress. Several infections including Giardia duodenalis, Cryptosporidium spp., Enterocytozoon bieneusi, Toxoplasma gondii present important zoonotic concerns across multiple regions Additionally, this synthesizes current knowledge on microbiota various body sites examines their functional significance health disease. The complex relationship between host represents a critical area research donkeys. Recent molecular advancements have enhanced our understanding diverse microbial ecosystems inhabiting different donkeys profound impact outcomes. As single-stomach herbivores, possess communities throughout digestive tracts that are essential for intestinal homeostasis nutritional processing. Significant variations composition exist segments, with hindgut displaying greater richness diversity compared to foregut. Beyond system, distinct profiles been characterized skin, oral cavity, reproductive tract, secretions such as milk. implications extend areas nutrition, immune function, disease susceptibility. Research demonstrates how dietary interventions, environmental stressors, physiological states significantly alter communities, correlating changes inflammatory markers, antioxidant responses, metabolic functions. specific signatures associated conditions like endometritis suggest potential microbiota-based diagnostics therapeutics. identification antibiotic-resistant strains Proteus mirabilis Klebsiella pneumoniae meat food safety requiring monitoring systems standardized protocols. These provide foundation improved healthcare management, targeted surveillance, protective measures those working or consuming donkey-derived products.

Язык: Английский

Процитировано

0

Application of Omics in Donkey Meat Research: A Review DOI Creative Commons
Qiying Zhu,

Yongdong Peng,

Xiaotong Liu

и другие.

Animals, Год журнала: 2025, Номер 15(7), С. 991 - 991

Опубликована: Март 29, 2025

This review comprehensively examines the molecular basis of donkey meat characteristics and growth-associated genes, integrating findings from multiple omics approaches. study nutritional profile meat, which is rich in protein, essential amino acids, unsaturated fatty acids. Through a systematic literature search across Web Science, Google Scholar, PubMed, Scopus databases (2000-2024), we collected analyzed data 400 research articles using predefined inclusion criteria focused on composition, approaches, quality parameters populations. The also evaluates various factors affecting quality, including breed differences, age, feeding management, storage conditions. Advanced genomic transcriptomic analyses have revealed numerous candidate such as ACTN3, BMP7, NR6A1, Wnt7a, HOXC8, LCORL, TPM2, TPM3, associated with growth traits characteristics, providing valuable insights for genetic improvement programs. Furthermore, discusses authentication methods ensuring preventing adulteration, highlighting integration traditional modern analytical

Язык: Английский

Процитировано

0

Insights into the Donkey Hindgut Microbiome Using Metagenome-Assembled Genomes DOI Creative Commons
Xiyan Kou,

Yihong Liu,

Fokun Xiang

и другие.

Animals, Год журнала: 2024, Номер 14(24), С. 3625 - 3625

Опубликована: Дек. 16, 2024

The gut microbiota plays an important role in the digestion, absorption, and metabolism of nutrients, as well immunity, health, behavior donkeys. While reference genomes microbial gene catalogs have been helpful understanding composition donkey, there is still a significant gap sequencing functional aspects donkey genomes. In this study, we analyzed metagenomic data from 26 donkeys’ samples successfully assembled 844 metagenome-assembled (MAGs). Surprisingly, 678 (80.33%) these MAGs appear to belong previously unidentified species. Our analysis further revealed total 292,980 predicted carbohydrate-active enzymes (CAZymes) 257,893 polysaccharide utilization loci (PULs). Interestingly, displayed relatively low similarity matches public databases. We found that higher abundances 36 cecum (such Prevotella, Desulfovibrio, Alistipes, Treponema_D) 9 dorsal colon Limimorpha, Saccharofermentans, Lactobacillus) were associated with diverse array carbohydrate-degrading pathways. Network identified Prevotella Dysosmobacter connectors, while Saccharofermentans Akkermansia shown provincial hubs. This suggests their crucial roles complex carbohydrate degradation hindgut These findings underscore complexity donkeys expand our microbiome. Overall, study provides comprehensive catalog genes, revealing novel offering new insights for future research on

Язык: Английский

Процитировано

1