Microplastic and the Enteric Nervous System: Effect of PET Microparticles on Selected Neurotransmitters and Cytokines in the Porcine Ileum DOI Open Access
Ismena Gałęcka, Jarosław Całka

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(21), С. 11645 - 11645

Опубликована: Окт. 30, 2024

Microplastic is an environmental hazard to which both animals and humans are exposed. Current reports show that it can cause inflammation, including in the gastrointestinal tract. To examine impact on ileum, 15 eight-week-old gilts (five individuals/group) were exposed PET microplastics (7.6 µm-416.9 µm) at a dose of 0.1 g/day or 1 for 28 days. The collected ileum fragments investigated cytokine concentrations (IL-1β, IL-6, IL-8, IL-10, TNF-α; ELISA test), neuron populations (cocaine amphetamine-regulated transcript, galanin, neuronal nitric oxide synthase, substance P, vesicular acetylcholine transporter, vasoactive intestinal peptide; immunofluorescence staining), morphometric parameters (histological analysis). Under influence MP-PET, there was reduction CART- GAL-positive neurons submucosal plexuses nNOS-, VAChT-, VIP-positive all plexuses. In contrast, increase myenteric plexus SP-positive IL-1β, TNF-α did not undergo statistically significant changes under low high MP-PET. histological structure exclusively concerned thinning mucosa muscularis externa. results support thesis MP-PET neutral ileal cells.

Язык: Английский

Microplastics in Animal-Derived Products and Their Potential Risks to Human Health DOI
Hao Zeng, Yujie Cui,

Runlin Shao

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118187 - 118187

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1
Exploring sustainable strategies for mitigating microplastic contamination in soil, water, and the food chain: A comprehensive analysis DOI Creative Commons

Udaratta Bhattacharjee,

Khanindram Baruah, Maulin P. Shah

и другие.

Environmental Chemistry and Ecotoxicology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1
Microplastics in Farmed Animals—A Review DOI Creative Commons
Maximilian Lackner,

Manuela Branka

Microplastics, Год журнала: 2024, Номер 3(4), С. 559 - 588

Опубликована: Сен. 30, 2024

Environmental pollution from plastics has become one of the biggest concerns globally. Microplastics (MPs) are plastic materials less than 5 mm in size. They remain environment for hundreds to thousands years without degrading, only breaking down further nanoplastics (NPs). Micro- and can be origin many diseases carry various pathogenic substances on their surface spread them throughout biosphere, starting with contained additives ending adsorbed toxins potentially microorganisms. Exposure routes humans animals through air, water food/feed. Due placement livestock—including ruminants, fish poultry—and at top food web, any water, air or soil eventually transferred livestock humans. The presence microplastics intestines aquaculture species, ruminants poultry, instance, was found cause a change intestinal microbial population and, as result, occurrence diseases. These particles have also been observed other organs such liver, kidneys, lung, spleen, heart, ovaries, testicles animals, which causes biochemical changes, structural destruction, malfunction. While complete extent negative health impacts remains still largely unknown, ubiquitous transmission chemicals organisms is notable issue, underscoring importance gaining more comprehensive understanding potential threats posed by animal ultimately human health, coupled need drastic reduction freight into environment. This review article summarizes recent findings effect micro- farmed ultimately, Action needed reduce number thereby humans, exposed.

Язык: Английский

Процитировано

4
An integrated evaluation of potentially toxic elements and microplastics in the highland soils of the northeastern Qinghai-Tibetan Plateau DOI

Apurva Kakade,

Qunying Zhang, Tom Wu

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137453 - 137453

Опубликована: Фев. 4, 2025

Язык: Английский

Процитировано

0
Toxicity Mechanisms of Microplastic and Its Effects on Ruminant Production: A Review DOI Creative Commons

Mao-Sen Su,

Shangquan Gan, Rui Gao

и другие.

Biomolecules, Год журнала: 2025, Номер 15(4), С. 462 - 462

Опубликована: Март 21, 2025

Plastic pollution has become one of the major environmental problems facing human beings in world today. waste accumulated environment forms plastic particles different sizes due to farming activities, climate change, ultraviolet light, microbial degradation, and animal chewing. The caused by microplastics a problem recent years, it is also research hotspot field ecological environment. More more studies have found that ruminants are exposed for long time, which seriously threaten their healthy growth. This paper introduces current situation pollution; properties effects on environment, beings, animals; summarizes types toxicity mechanisms microplastics; concludes main ways enter harm them. In addition, shortcomings future development summarized prospected provide theoretical reference related alleviating influence ruminant production.

Язык: Английский

Процитировано

0
Exploring the influence of polystyrene-nanoplastics on two distinct in vitro systems in farm animals: A pilot study DOI Creative Commons
Francesca Corte Pause, Anja Baufeld,

Susy Urli

и другие.

The Science of The Total Environment, Год журнала: 2025, Номер 976, С. 179378 - 179378

Опубликована: Апрель 9, 2025

The harmful effects of micro- and nanoplastics (MNPs) on the aquatic ecosystem are already well established, several studies have demonstrated that MNPs can contaminate soil. However, impact farm animals, whose products intended for human consumption, as accumulation translocation these particles in their bodies, is less investigated not understood. To address this issue, we evaluated cellular uptake three different concentrations (5, 25, 75 μg/mL) 100 nm polystyrene (PS-NPs) ovarian bovine granulosa cells (GCs) porcine myoblasts derived from skeletal muscle satellite vitro primary cell culture models. PS-NPs was shown all tested, both GCs myoblasts. results reported a significant decrease viability (P < 0.05) tested compared to control. steroid hormone production mRNA expression GC physiology marker genes were affected. showed mean confluence after exposure concentration μg/mL This may be indicative an initial inhibition fibre formation. viability, proliferative capacity, myogenesis-associated As there currently no standard method assessing quantity overcome anatomical barriers accumulate various parts body, recognizing implications animals help us better comprehend potential risks health. knowledge critical developing informed treatment avoidance strategies, ensuring safety food consume environment which it produced.

Язык: Английский

Процитировано

0
Microplastics and Nanoplastics as Environmental Contaminants of Emerging Concern: Potential Hazards for Human Health DOI Open Access
Rita Khanna, Abhilash P. Chandra,

Shaundeep Sen

и другие.

Sustainability, Год журнала: 2024, Номер 16(19), С. 8704 - 8704

Опубликована: Окт. 9, 2024

With nearly 40% of the total plastics produced being used for packaging, up to five trillion plastic bags are consumed in world annually. The inadequate disposal waste and its persistence has become a serious challenge/risk environment, health, well-being living creatures, including humans. natural degradation is extremely slow; large pieces may break down into microplastics (MPs) (1 μm–5 mm) or nanoplastics (NPs) (<1000 nm) after protracted physical, chemical, and/or biological degradations. A brief overview transport micro- aquatic, terrestrial, atmospheric environments presented. Details provided on exposure routes these materials their entry humans other biota through ingestion, inhalation, dermal contact. greatest concern cumulative impact heterogeneous secondary MPs NPs planetary human health. Inhaled have been shown affect upper respiratory tract, lower alveoli; prolonged can lead chronic inflammatory changes systemic disease. These also autoimmune diseases health conditions, atherosclerosis malignancy. Sustainable mitigation strategies reduce MPs/NPs include source reduction, material substitution, filtration purification, transformation value-added materials, technological innovations, etc. Multidisciplinary collaborations across fields medicine, public environmental science, economics, policy required help limit detrimental effects widespread environment.

Язык: Английский

Процитировано

3
Advances in Microplastic Characterization: Spectroscopic Techniques and Heavy Metal Adsorption Insights DOI Creative Commons
M. Vasudeva, Anish Kumar Warrier,

V. B. Kartha

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 118111 - 118111

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

3
Disposition of [ 14 C]-polystyrene microplastics after oral administration to lactating sheep DOI

Weilin L. Shelver,

Amy M. McGarvey,

Lloyd O. Billey

и другие.

Food Additives & Contaminants Part A, Год журнала: 2024, Номер 41(9), С. 1132 - 1143

Опубликована: Июль 22, 2024

Microplastics have become a ubiquitous contaminant, but their fate in food animals is largely unknown. In this study, [

Язык: Английский

Процитировано

2
Microplásticos en materia fecal de rumiantes en Ecuador DOI Creative Commons

Iván Roberto González Puetate,

Galo Ernesto Martínez Cepeda,

Pablo Torres Lasso

и другие.

Ciencia Veterinaria, Год журнала: 2024, Номер 26(2), С. 114 - 129

Опубликована: Июль 12, 2024

The current study provides evidence of the presence microplastics in feces cattle, sheep, and goats under production Ecuador as a relevant indicator understanding fragmentation processes, biodistribution mechanisms, possible effects contamination agri-food chain.A total 300 samples ruminant were analyzed field, observational, cross-sectional study.Using saturated salt solution flotation technique, 75.67% found to be contaminated with microplastics.Statistical analyses, which included frequency distribution tables, Pearson's Chi-Square test, Z-test, Odds Ratio using SPSS version 26 software, showed that type feeding is significant factor feces.In addition, an 87% increase reduction was observed grazing systems compared those receiving balanced supplemental feeding.Finally, there 85.3% cattle near roads.These results suggest importance considering feed environment when addressing microplastic chain its potential impact on one health systems.

Язык: Английский

Процитировано

1