Effects of High‐Dose Vitamin D3 Supplementation on Pig Performance, Vitamin D Content in Meat, and Muscle Transcriptome in Pigs DOI
Anna Steg, Maria Oczkowicz, Małgorzata Świątkiewicz

и другие.

Journal of Animal Physiology and Animal Nutrition, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 20, 2024

ABSTRACT Vitamin D is known for its role in calcium homeostasis, bone health, and immune function. Recent research has explored effects on muscle functionality meat quality pigs. This study examined high‐dose vitamin D3 supplementation pigs, focusing growth, blood tissue levels, transcriptome changes. Thirty pigs were divided into three groups, given different amounts of oral supplementation: control, 5000 IU/kg 10,000 D3. Biochemical haematological parameters, content muscle, kidney evaluated. RNA‐seq qPCR analysed changes, while gene set enrichment analysis (GSEA) identified expression enrichments. Results showed that altered parameters like platelet anisocytosis glucose levels but did not affect body weight, weight gain, or feed intake. Kidney increased with supplementation. The ( longissimus dorsi ) increased, suggesting the potential biofortified pork, although still optimal as a dietary source. Transcriptome revealed minimal only interferon‐gamma receptor 2 IFNGR2 differentially expressed at highest dose. GSEA indicated ATP metabolic processes electron transport chain genes group, system, cholesterol, steroid, fatty acid metabolism group. Despite literature growth improvement, this found limited.

Язык: Английский

Review of Liquid Vitamin A and E Formulations in Veterinary and Livestock Production: Applications and Perspectives DOI Creative Commons
Yauheni Shastak,

Wolf Pelletier

Veterinary Sciences, Год журнала: 2024, Номер 11(9), С. 421 - 421

Опубликована: Сен. 9, 2024

Vitamins A and E are vital fat-soluble micronutrients with distinct yet intertwined roles in various biological processes. This review delves into their functions, nutritional requirements across different animal species, the consequences of deficiencies, impact liquid formulations on veterinary medicine livestock production. Vitamin exists multiple forms, essential for vision, immunity, growth, while vitamin acts primarily as an antioxidant, safeguarding cell membranes from oxidative damage. Hypovitaminosis these vitamins can lead to severe health consequences, affecting reproduction, neurological functions. Hence, supplementation, particularly through innovative formulations, becomes pivotal addressing deficiencies enhancing overall productivity. Injectable forms show promise reproductive performance, immune function livestock. Administering drinking water offers a convenient way enhance productivity, during times stress or increased needs. Liquid drops offer flexible effective solution practice, allowing precise dosing easy administration, companion animals. Future research may aim optimize explore targeted therapies precision feeding via nutrigenomics, promising advancements

Язык: Английский

Процитировано

1

Exploring the role of riboflavin in swine well-being: a literature review DOI Creative Commons
Yauheni Shastak,

Wolf Pelletier

Porcine Health Management, Год журнала: 2024, Номер 10(1)

Опубликована: Окт. 31, 2024

Riboflavin (vitamin B

Процитировано

0

The E‐volution in swine nutrition: Current perspectives on vitamin E DOI Creative Commons
Yauheni Shastak,

Wolf Pelletier

Animal Research and One Health, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 7, 2024

Abstract This review provides an in‐depth analysis of vitamin E's multifaceted role in swine nutrition, incorporating both traditional insights and contemporary research. It begins with exploration E from evolutionary perspective, followed by a detailed examination its absorption, metabolism, excretion swine. The emphasizes the micronutrient's critical functions physiology, particularly antioxidant properties emerging links to epigenetics, which include deoxyribonucleic acid methylation, histone modification, noncoding ribonucleic regulation. interactions other dietary components are discussed, along established nutritional requirements current recommendations for supplementation. Additionally, health benefits performance improvements associated presented, emphasizing importance immune function, growth, meat quality. Despite extensive research, identifies gaps understanding bioavailability long‐term impacts different isoforms supra‐nutritional supplementation levels. concludes discussion research future directions, need studies on effects high‐dose influence environmental factors metabolism. Through this comprehensive synthesis, study aims provide holistic essential contributions goal informing better practices enhancing productivity.

Язык: Английский

Процитировано

0

Effects of High‐Dose Vitamin D3 Supplementation on Pig Performance, Vitamin D Content in Meat, and Muscle Transcriptome in Pigs DOI
Anna Steg, Maria Oczkowicz, Małgorzata Świątkiewicz

и другие.

Journal of Animal Physiology and Animal Nutrition, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 20, 2024

ABSTRACT Vitamin D is known for its role in calcium homeostasis, bone health, and immune function. Recent research has explored effects on muscle functionality meat quality pigs. This study examined high‐dose vitamin D3 supplementation pigs, focusing growth, blood tissue levels, transcriptome changes. Thirty pigs were divided into three groups, given different amounts of oral supplementation: control, 5000 IU/kg 10,000 D3. Biochemical haematological parameters, content muscle, kidney evaluated. RNA‐seq qPCR analysed changes, while gene set enrichment analysis (GSEA) identified expression enrichments. Results showed that altered parameters like platelet anisocytosis glucose levels but did not affect body weight, weight gain, or feed intake. Kidney increased with supplementation. The ( longissimus dorsi ) increased, suggesting the potential biofortified pork, although still optimal as a dietary source. Transcriptome revealed minimal only interferon‐gamma receptor 2 IFNGR2 differentially expressed at highest dose. GSEA indicated ATP metabolic processes electron transport chain genes group, system, cholesterol, steroid, fatty acid metabolism group. Despite literature growth improvement, this found limited.

Язык: Английский

Процитировано

0